2010

TACC3-TSC2 maintains nuclear envelope structure and controls cell division.
Gómez-Baldó L., Schmidt S., Maxwell C.A., Bonifaci N., Gabaldón T., Vidalain P-O., Senapedis W., Kletke A., Rosing M., Barnekow A., Rottapel R., Capellá G., Vidal M., Astrinidis A.^§, Piekorz R.P.^§, Pujana M.A.^§
§ corresponding authors
Cell Cycle 9(6): 1143-1155

Commented in:

• TACCing on new functions for the TSC2 tumor suppressor.
  Golemis E.A.
  Cell Cycle 9(7): 1232-1233
• Interaction of TACC3 and TSC2 at the nuclear envelope and mitotic structures.
  Ertych N., Bastians H.
  Cell Cycle 9(7): 1233
  

The transcription factor SP1 regulates centriole function and chromosomal stability through a functional interaction with the mammalian target of rapamycin/raptor complex.
Astrinidis A., Kim J., Kelly C.M., Olofsson B.A., Torabi B., Sorokina E.M., Azizkhan-Clifford J.
Genes Chromosomes Cancer 49(3): 282-297

2009

The p53 target Plk2 interacts with TSC proteins impacting mTOR signaling, tumor growth, and chemosensitivity under hypoxic conditions.
Matthew E.M., Hart L.S., Astrinidis A., Navaraj A., Dolloff N.G., Dicker D.T., Henske E.P., El-Deiry W.S.
Cell Cycle 8(24): 4168-76

Estrogen promotes the survival and pulmonary metastasis of tuberin-null cells.
Yu J.J., Robb V.A., Morrison T.A., Ariazi E.A., Karbowniczek M., Astrinidis A., Wang C., Hernandez-Cuebas L., Seeholzer L.F., Nicolas E., Hensley H., Jordan V.C., Walker C.L., Henske EP
Proceedings of the National Academy of Sciences USA 106(8): 2345-40

2006

Mutation detection in tumor suppressor genes using archival tissue specimens.
Astrinidis A. and Henske EP
Methods Molecular Medicine 126: 185-196 (Congenital Heart Disease: Molecular Diagnostics, M. Kearns-Jonker ed.)

Frequent hyperphosphorylation of ribosomal protein S6 in lymphangioleiomyomatosis-associated angiomyolipomas. (2006)
Robb VA, Astrinidis A., Henske EP
Modern Pathology 19(6): 839-46

Hamartin, the tuberous sclerosis complex 1 gene product, interacts with polo-like kinase 1 in a phosphorylation-dependent manner. (2006)
Astrinidis A., Senapedis W., Henske EP
Human Molecular Genetics 15(2): 287-97

2005

Tuberous sclerosis complex: linking growth and energy signaling pathways with human disease. (2005)
Astrinidis A. and Henske EP
Oncogene 24(50): 7475-81. Review.

2004

Aberrant cellular differentiation and migration in renal and pulmonary tuberous sclerosis complex.
Astrinidis A. and Henske EP
Journal of Child Neurology 19(9): 710-5. Review.

Regulation of B-Raf kinase activity by tuberin and Rheb is mTOR independent.
Karbowniczek M., Cash T., Cheung M., Robertson G.P., Astrinidis A., Henske EP
Journal of Biological Chemistry 279(29): 29930-37

2003

Cell cycle-regulated phosphorylation of hamartin, the product of the tuberous sclerosis complex 1 gene, by CDK1/cyclin B.
Astrinidis A., Senapedis W., Coleman T.R., Henske EP
Journal of Biological Chemistry 278(51): 51372-79

Estradiol and tamoxifen stimulate lymphangiomyomatosis-associated angiomyolipoma cell growth and activate both genomic and non-genomic signaling pathways. (2004)
Yu J.J., Astrinidis A., Howard S., Henske EP
American Journal of Physiology - Lung Cell Molecular Physiology 286(4): L694-700

2002

Tuberin, the Tuberous Sclerosis 2 tumor suppressor gene product, regulates Rho activation, cell adhesion, and cell migration. (2002)
Astrinidis A., Cash T., Hunter D., Walker C., Chernoff J., Henske EP
Oncogene 21(55): 8470-6

Recurrent lymphangiomyomatosis after transplantation: genetic analyses reveal a metastatic mechanism.
Karbowniczek M., Astrinidis A., Balsara B.R., Testa J.R., Lium J.H., Colby T.V., McCormack F.X., Henske EP
American Journal of Respiratory and Critical Care Medicine 167(7): 976-82

Expression of wild type and mutant TSC2, but not TSC1, causes an increase in the G1 fraction of the cell cycle in HEK293 cells.
Khare L., Astrinidis A., Senapedis W., Adams P.D., Henske EP
Journal of Medical Genetics 39(9): 676-80

2001

Chromosome 16 loss of heterozygosity in tuberous sclerosis and sporadic lymphangiomyomatosis.
Yu J.J., Astrinidis A., Henske EP
American Journal of Respiratory and Critical Care Medicine 164(8 Pt 1): 1537-40

2000

Mutations in the tuberous sclerosis complex gene TSC2 are a cause of sporadic pulmonary Lymphangioleiomyomatosis.
Carsillo T., Astrinidis A., Henske EP
Proceedings of the National Academy of Sciences USA 97(11): 6085-90

Mutational analysis of the tuberous sclerosis gene TSC2 in patients with pulmonary Lymphangioleiomyomatosis.
Astrinidis A., Khare L., Carsillo T., Smolarek T., Au K.S., Northrup H., Henske EP
Journal of Medical Genetics 37(1): 55-7

1999

Heterogeneity of four beta-thalassaemia mutations in Greece.
Valianou M.G., Kouvatsi A., Hassapopoulou-Matamis H., Astrinidis A., Triantaphyllidis C.
Hemoglobin 23(1): 79-82

Mitochondrial DNA polymorphism in the Vietnamese population.
Ivanova R., Astrinidis A., Lepage V., Djoulah S., Wijnen E., Vu-Trieu A.N., Hors J., Charron D.
European Journal of Immunogenetics 26(6): 417-422

Mitochondrial DNA polymorphisms of a west Algerian population (Oran region).
Ivanova R., Astrinidis A., Djoulah S., Lepage V., Wijnen E., Hors J., Charron D.
Biomedical Pharmacotherapy 53(8): 386-92

Mitochondrial DNA polymorphism in the French population.
Ivanova R., Astrinidis A., Lepage V., Kouvatsi A., Djoulah S., Hors J., Charron D.
Biomedical Pharmacotherapy 53(4): 207-12

Mitochondrial DNA polymorphism in the Bulgarian population.
Ivanova R., Astrinidis A., Lepage V., Wijnen E., Naumova E., Charron D.
Balkan Journal of Medical Genetics 2: 9-16

1998

Novel intragenic polymorphisms in the tuberous sclerosis 2 (TSC2) gene.
Astrinidis A.^§, Kouvatsi A., Nahmias J., Povey S., Pandeliadis C., Danzaki A.,Schneider M., Triantaphyllidis C.
^§ corresponding author
Human Mutation 12: 217 (abstract) / on line mutation in brief #184

Molecular Study of Tuberous Sclerosis.
Astrinidis A.
Ph.D. Thesis, Aristotle University of Thessaloniki, Thessaloniki, Greece

1994

Mitochondrial DNA polymorphisms in Northern Greece.
Astrinidis A. and Kouvatsi A.
Human Biology 66(4): 601-611