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Emfietzoglou Dimitris, Ph.D.

Medical Physics Laboratory

University of Ioannina Medical School

Ioannina GR-45110

Tel:  (30) 26510 07741

e-mail: demfietz@uoi.gr

https://medphysicslab.med.uoi.gr/

 

 

 

Biographical Sketch

 

1991   BSc (Physics), University of Athens, Greece

1993   MSc (Radiation Science), Georgetown University, Washington DC, USA

1996   PhD (Radiation Biophysics), Georgetown University, Washington DC, USA

1997   National service in the Greek Navy (2 years)

1999   Post Doctoral Fellow (Radiation Medicine), Georgetown University, Washington DC, USA

2000   Lecturer, Medical Physics Laboratory, University of Ioannina Medical School, Ioannina, Greece

2005   Assistant Professor, Medical Physics Laboratory, University of Ioannina Medical School, Ioannina, Greece

2014   Associate Professor, Medical Physics Laboratory, University of Ioannina Medical School, Ioannina, Greece

2019   Professor, Medical Physics Laboratory, University of Ioannina Medical School, Ioannina, Greece

 

 

Research interests

 

·      Interaction of charged particles with condensed media and nanostructures (cross sections)

·      Monte Carlo radiation transport simulations (track-structure and condensed-history methods)

·      Dosimetry of targeted radionuclide therapy w/ β- and Auger-emitters (cellular level)

·      Dosimetry of ion-beam radiotherapy (Bragg peak characteristics)

·      Radiation biophysics (DNA damage and cell survival predictions)

·      Microdosimetry (radiation quality issues)

·      Development of the GEANT4-DNA code and applications to Medical Physics

 

 

Administrative experience

 

2020-      Director, Division of Morphological & Clinical-Laboratory Sciences, Dept. of Medicine, Univ. of Ioannina

2019-      Director, Medical Physics Laboratory, Dept. of Medicine, Univ. of Ioannina

2019-      Steering Committee Member, MSc program in Medical Radiation Physics (Univs of Athens, Thessaloniki, Crete, Ioannina, Thrace)

2010-      Member of Faculty Assembly, Dept. of Medicine, Univ. of Ioannina

2010-     Committee Member, Physics Entrance Exam. (transfer applicants), Dept. of Medicine, Univ. of Ioannina

2010-11   Medical School Representative, University Library Committee, Univ. of Ioannina

 

 

International Committees

 

·      Scientific Committee MICROS 2017: 17th International Symposium on Microdosimetry, November 5-10, 2017, Venice, Italy.

·      Scientific Advisory Committee: 4th Geant4 Monte Carlo Workshop for Radiotherapy, Imaging, and Radiation Protection, 2-8 December, 2019, Wollongong, Australia.

·      Committee Member International Commission on Radiation Units and Measurements (ICRU) Report no. 90:

Key Data for Ionizing Radiation Dosimetry: Measurement Standards and Applications. International Commission on Radiation Units and Measurements (Bethesda, Maryland), Journal of the ICRU vol. 14, pp 1-110 (2014).

·      Committee Member International Commission on Radiation Units and Measurements (ICRU) Report no. 96:

Dosimetry-Guided Radiopharmaceutical Therapy. International Commission on Radiation Units and Measurements (Bethesda, Maryland), Journal of the ICRU vol. 22, pp 1-212 (2022).

 

 

Supervision

 

Research Associates

Ioanna Kyriakou (PhD, Physics, Univ. of Lancaster, UK) 2008-2021

 

Post-doctoral researchers

Christos Bousis (PhD, Medical Physics, Univ. of Ioannina) 2009-2012

 

PhD students

Christina Kotroumpelou (Medical Physics, Univ. of Ioannina), PhD thesis in progress

Alexis Papadopoulos (Medical Physics, Univ. of Ioannina), PhD thesis in progress

Martin Sefl (Radiation Dosimetry, Nuclear Physics Institute of the Academy of Sciences, Czech Republic), PhD completed 2018*

Anne-Marie Forney (Chemical Physics, University of Maryland, USA), PhD completed 2018*

George Papamichael (Applied Mathematics, Brown Univ., USA), PhD completed 2009

Christos Bousis (Medical Physics, Univ. of Ioannina, Greece), PhD completed 2009

*visiting

 

Master students

Georgia Eleftheriadou (Medical Physics, Univ. of Ioannina), MSc thesis in progress

Stefanos Margis (Physics, Univ. of Ioannina), MSc thesis in progress

Christina Kotroumpelou (Medical Physics, Univ. of Ioannina), MSc thesis completed 2020

Dimos Dimopoulos (Medical Physics, Univ. of Ioannina), MSc thesis completed 2006

Kostantina Karava (Medical Physics, Univ. of Ioannina), MSc thesis completed 2004

Alexandros Papakostas (Medical Physics, Univ. of Ioannina), MSc thesis completed 2003

Kostas Skordos (Medical Physics, Univ. of Ioannina), MSc thesis completed 2002

 

Undergraduate students

Constantina Tzeikou (Physics, Univ. of Ioannina), BSc thesis in progress

Evelina Christana (Physics, Univ. of Ioannina), BSc thesis in progress

Nikolaos Chlis (Physics, Univ. of Ioannina), BSc thesis in progress

Dimitris Dallalas (Physics, Univ. of Ioannina), BSc thesis in progress

John Prokopiou (Physics, Univ. of Ioannina), BSc thesis in progress

Aggeliki Bei (Physics, Univ. of Ioannina), BSc thesis in progress

Danai Tsoukala (Physics, Univ. of Ioannina), BSc thesis completed 2021

Georgia Eleftheriadou (Physics, Univ. of Ioannina), BSc thesis completed 2020

Kyriaki Niapou (Physics, Univ. of Ioannina), BSc thesis completed 2020

Aggeliki Gavonatsiou (Physics, Univ. of Ioannina), BSc thesis completed 2020

Maria Magouni (Physics, Univ. of Ioannina), BSc thesis completed 2019

Stefanos Margis (Physics, Univ. of Ioannina), BSc thesis completed 2019

Christina Kotroumpelou (Physics, Univ. of Ioannina), BSc thesis completed 2018

Antonis Tsologiannis (Physics, Univ. of Ioannina), BSc thesis completed 2018

Christos Politidis (Physics, Univ. of Ioannina), BSc thesis completed 2016

Varvara Driaga (Physics, Univ. of Ioannina), BSc thesis completed 2016

Stiliani Zelilidou (Physics, Univ. of Ioannina), BSc thesis completed 2016

Kalliopi Kardomatea (Physics, Univ. of Ioannina), BSc thesis completed 2016

Pantelis Bourazanis (Physics, Univ. of Ioannina), BSc thesis completed 2014

Stefanos Tanabasidis (Physics, Univ. of Ioannina), BSc thesis completed 2012

Christos Langouras (Physics, Univ. of Ioannina), BSc thesis completed 2011

Marios Sotiropoulos (Physics, Univ. of Ioannina), BSc thesis completed 2008

Kostas Zogopoulos (Physics, Univ. of Ioannina), BSc thesis completed 2003

Vasilis Kostakis (Physics, Univ. of Ioannina), BSc thesis completed 2002

 

 

Research Grants (Total funding >800k EUR)

 

·        University of Ioannina Research Committee 2001-2002 (PI)

·        Industrial Sponsorship 2002-2005 (PI)

·        Center for Drug Delivery Research (London, UK) 2005-2007 (co-PI)

In collaboration with Univ. of London (UK)

·        University of Ioannina Research Committee 2008-2009 (PI)

·        European Commission (FP7-HEALTH) 2008-2011 (co-PI)

In collaboration with Univ. of London (UK), Univ. of Trieste (Italy), CNRS (France),

Nanocyl S.A. (Belgium), UCB Pharma S.A. (UK), Helmholtz Institute (Germany)  

·        Ministry of Science and Innovation of Spain 2011-2014 (ext-PI)

In collaboration with Univ. of Alicante (Spain) and Univ. of Murcia (Spain)

·        European Commission (FP7-PEOPLE-ITN) 2012-2015 (co-PI)

In collaboration with Univ. of Oxford (UK), Kings College London (UK), Univ. of Trieste (Italy),

CNRS (France), Materials Science Institute of Barcelona (ICMAB, Spain), Catalan Institute of Nanotechnology (Spain),

HIPC (Czech Republic), IBA S.A. (France)  

·        Ministry of Economy and Competitiveness of Spain 2015-2018 (ext-PI)

In collaboration with Univ. of Alicante (Spain) and Univ. of Murcia (Spain)

·        France-Greece Project International de Cooperation Scientific (PICS) 2016-2018 (co-PI)

In collaboration with Univ. of Bordeaux (France), Univ. of Toulouse, (France), and CNRC (France)

·        Australian Research Council 2017-2019 (ext-PI)

In collaboration with University of Wollongong (Australia), CNRS (France), Queen’s University of Belfast (N. Ireland)

·        European Space Agent (ESA) 2018-2021 (co-PI)

In collaboration with University of Athens (Greece), National Technical University of Athens (Greece), Institute of Accelerating Systems and Applications (Greece)

·        France-Greece Project International de Cooperation Scientific (PICS) 2019-2021 (co-PI)

In collaboration with Univ. of Bordeaux (France), Univ. of Toulouse, (France), and CNRC (France)

·        European Space Agent (ESA) 2021-2023 (co-PI)

In collaboration with CEA, CNRS/IN2P3, CENBG, IRSN (France), G4AI Ltd. (UK), Sward SRL, INFN (Italy), Sevilla University (Spain)

 

 

PAPERS IN PEER-REVIEW JOURNALS

Citations: 3800+ (Scopus); 5000+ (GoogleScholar)

h-index: 35 (Scopus); 42 (GoogleScholar)

 

 

135.    Koval N.E., Koval P., Da Pieve F., Kohanoff J., Artacho E., Emfietzoglou D. Inelastic scattering of electrons in water from first principles: cross sections and inelastic mean free path for use in Monte Carlo track-structure simulations of biological damage. Royal Society Open Science 9:212011, 19pp (2022).

 

134.    Lindborg L., Lillhök J., Kyriakou I., and Emfietzoglou D. Dose-mean lineal energy values for electrons by different Monte Carlo codes: Consequences for estimates of radiation quality in photon beams. Medical Physics 49:1286-1296 (2022)

 

133.    Kyriakou I., Emfietzoglou D., Incerti S. Status and extension of the Geant4-DNA dielectric models for application to electron transport. Frontiers in Physics 9:711317, 7pp (2022)

 

132.     Kyriakou I., Sakata D., Tran H.N., Perrot Y., Shin W.-G., Lampe N., Zein S., Bordage M.C., Guatelli S., Villagrasa C., Emfietzoglou D., Incerti S. Review of the Geant4-DNA simulation toolkit for radiobiological applications at the cellular and DNA level. Cancers 14:35, 26pp (2022)

 

131.    Sakata D., Suzuki M., Hirayama R., Abe Y., Muramatsu M., Sato S., Belov O., Kyriakou I., Emfietzoglou D., Guatelli S., Incerti S., Inaniwa T. Performance evaluation for repair of HSGc-C5 carcinoma cell using Geant4-DNA. Cancers 13:6046, 16pp (2021)

 

130.    Shin W.G., Sakata D., Lampe N., Belov O., Tran N.H., Petrovic I., Ristic‐Fira A., Dordevic M., Bernal M.A., Bordage M.C. Francis Z.,

Kyriakou I., Perrot Y., Sasaki T., Villagrasa C., Guatelli S., Breton V., Emfietzoglou D., and Sebastien Incerti. A Geant4‐DNA Evaluation of       Radiation‐Induced DNA Damage on a Human Fibroblast. Cancers 13:4940, 17pp (2021)

 

129.    Kalospyros S.A., Gika V., Nikitaki Z., Kalamara A., Kyriakou I., Emfietzoglou D., Kokkoris M., Georgakilas A.G. Monte Carlo Simulation-Based Calculations of Complex DNA Damage for Incidents of Environmental Ionizing Radiation Exposure. Applied Sciences 11:8985, 21pp (2021)

 

128.    Kyriakou I., Tremi I., Georgakilas A.G., Emfietzoglou D. Microdosimetric investigation of the radiation quality of low-medium energy electrons using Geant4-DNA. Applied Radiation and Isotopes 72:109654, 15pp (2021)

 

127.    Kalospyros S.A., Nikitaki Z., Kyriakou I., Kokkoris M., Emfietzoglou D. and Georgakilas A.G. A Mathematical Radiobiological Model (MRM) to Predict Complex DNA Damage and Cell Survival for Ionizing Particle Radiations of Varying Quality. Molecules 26:840, 30pp (2021)

 

126.    Sakata D., Belov O., Bordage M.C. Emfietzoglou D., Guatelli S., Inaniwa T., Ivanchenko V., Karamitros M., Kyriakou I., Lampe N., Petrovic I., Ristic-Fira A., Shin W.-G., Incerti S. Fully integrated Monte Carlo simulation for evaluating radiation induced DNA damage and subsequent repair using Geant4-DNA. Scientific Reports 10:20788, 13pp (2020)

 

125.    Shingledecker C.N., Incerti S., Ivlev A., Emfietzoglou D., Kyriakou I., Vasyunin A., Caselli P. Cosmic ray tracks in astrophysical ices: Modeling with the Geant4-DNA Monte Carlo Toolkit. Astrophysical Journal 904:189, 13pp (2020)

 

124.    Engels E., Bakr S., Bolst D., Sakata D., Li N., Lazarakis P., McMahon S., Ivanchenko V., Rosenfeld A., Incerti S., Kyriakou I., Emfietzoglou D., Lerch M., Tehei M., Corde S., Guatelli S. Advances in modelling gold nanoparticle radiosensitization using new Geant4-DNA physics models. Physics in Medicine and Biology 65:225017, 16pp (2020)

 

123.    Chatzipapas K.P., Papadimitroulas P., Emfietzoglou D., Kalospyros S.A., Hada M., Georgakilas A.G., Kagadis G.C. Ionizing Radiation and Complex DNA Damage: Quantifying the Radiobiological Damage Using Monte Carlo Simulations. Cancers 12:799, 23pp (2020)

 

122.    Wang J. T.-W., Spinato C., Klippstein R., Costa P. M., Martincic M., Pach E., Ruiz de Garibay A. P., Ménard-Moyon C., Feldman R., Michel Y., Sefl M., Kyriakou I., Emfietzoglou D., Saccavini J.-C., Ballesteros B., Tobias G.,  Bianco A., Al-Jamal K.T. Neutron-irradiated antibody-functionalised carbon nanocapsules for targeted cancer radiotherapy. Carbon 162:410-422 (2020)

121.    Margis S., Magouni M., Kyriakou I., Georgakilas A.G., Incerti S. and Emfietzoglou D. Microdosimetric calculations of the direct DNA damage induced by low energy electrons using the Geant4-DNA Monte Carlo code. Physics in Medicine and Biology 65:045007, 17pp (2020).

 

120.    Wang J. T.-W., Klippstein R., Martincic M., Pach E., Feldman R., Sefl M., Michel Y., Asker D., Sosabowski J.K., Kalbac M., Da Ros T., Ménard-Moyon C., Bianco A., Kyriakou I., Emfietzoglou D., Saccavini J.-C., Ballesteros B., Al-Jamal K.T., Tobias G. Neutron Activated 153Sm Sealed in Carbon Nanocapsules for In Vivo Imaging and Tumor Radiotherapy. ACS Nano 14:129-141 (2020).

119.    Tang N., Bueno M., Meylan S., Perrot Y., Tran H.N., Freneau A., Dos Santos M., Vaurijoux A., Gruel G., Bernal M.A., Bordage M.-C., Emfietzoglou D., Francis Z., Guatelli S., Ivanchenko V., Karamitros M., Kyriakou I., Shin W.-G., Incerti S., Villagrasa C. Assessment of radioinduced damage in endothelial cells irradiated with 40 kVp, 220 kVp and 4 MV X-rays by means of micro and nanodosimetric calculations. International Journal of Molecular Sciences 20:6204, 19pp (2019).

 

118.    Shin W.-G., Ramos-Mendez J., Faddegon B., Tran H.N., Villagrasa C., Perrot Y., Okada S., Karamitros M., Emfietzoglou D., Kyriakou I., Bordage M.C., Sakata D., Guatelli S., Choi H.J., Min C.H., Lee S.B., and Incerti S. Evaluation of the influence of physical and chemical parameters on water radiolysis simulationsunder MeV electron irradiation using Geant4-DNA. Journal of Applied Physics 126:114301, 13pp (2019)

 

117.    Sakata D., Kyriakou I.,  Tran H.N., Bordage M.-C., Rosenfeld A.B., Ivanchenko V., Incerti S., Emfietzoglou D., Guatelli S. Electron track structure simulations in a gold nanoparticle using Geant4-DNA. Physica Medica: European Journal of Medical Physics 63:98-104 (2019)

 

116.    Sakata D., Lampe N., Karamitos M., Kyriakou I., Belov O., Barberet P., Bernal M.A., Bordage M.-C., Brown J.M.C., Francis Z., Ivanchenko V., Murakami K., Okada S., Petrovic I., Ristic-Fira A., Sasaki T., Seznec H., Shin W.-G., Tang N., Tran H.N., Torfeh E., Villagrasa C., Emfietzoglou D., Nieminen P., Guatelli S., Incerti S. Evaluation of early radiation DNA damage in a fractal cell nucleus model using Geant4-DNA. Physica Medica: European Journal of Medical Physics 62:152-157 (2019)

 

115.    Incerti S., Kyriakou I., Bordage M.C., Guatelli S., Ivanchenko V., Emfietzoglou D. Monte Carlo simulation of proximity functions in liquid water for electrons, protons and alpha particles using Geant4-DNA. Journal of Applied Physics 125:104301, 13pp (2019)

 

114.    Kyriakou I., Ivanchenko V., Sakata D., Bordage M.C., Guatelli S., Incerti S., Emfietzoglou D. Influence of track structure and condensed history physics models of Geant4 to nanoscale electron transport in liquid water. Physica Medica: European Journal of Medical Physics 58:149-154 (2019)

 

113.    Shin W.-G., Bordage M.-C., Emfietzoglou D., Kyriakou I., Sakata D., Min C.H., Lee S.B., Guatelli S., Incerti S. Development of a new Geant4-DNA electron elastic scattering model for liquid-phase water using the ELSEPA code. Journal of Applied Physics 124:224901, 15pp (2018)

 

112.    Sakata D., Kyriakou I., Okada S., Tran H., Lampe N., Guatelli S., Bordage M.C., Ivantchenko V.N, Murakami K., Sasaki T., Emfietzoglou D., Incerti S. Geant4-DNA track-structure simulations for gold nanoparticles: the importance of electron discrete models in nanometer volumes. Medical Physics 45:2230-2242 (2018)

 

111.    Lazarakis P., Incerti S. , Ivanchenko V. , Kyriakou I.,  Emfietzoglou D., Corde S., Rosenfeld A.B., Lerch M., Tehei M., Guatelli S. Investigation of Track Structure and Condensed History physics models for applications in radiation dosimetry on a micro and nano scale in Geant4. Biomedical Physics & Engineering Express 4:024001, 11pp (2018)

 

110.    Emfietzoglou D., Papamichael G., Nikjoo H. Monte Carlo electron track structure calculations in liquid water using a new model dielectric response function. Radiation Research 188:355-368 (2017)

 

109.    Kyriakou I., Emfietzoglou D., Ivantchenko V.N., Bordage M.C., Guatelli S., Lazarakis P., Tran H., Incerti S. Microdosimetry of electrons in liquid water using the low-energy models of Geant4. Journal of Applied Physics 122:024303, 17pp (2017)

 

108.    Garcia-Molina R., Abril I., Kyriakou I., Emfietzoglou D., Inelastic scattering and energy-loss of swift electron beans in relevant biological materials. Surface and Interface Analysis 49:11-17 (2017)

 

107.    Emfietzoglou D., Kyriakou I., Garcia-Molina R., Abril I., Inelastic mean free path of low-energy electrons in condensed media: Beyond the standard models. Surface and Interface Analysis 49:4-10 (2017)

 

106.    Sakata D., Incerti S., Bordage M.C., Lampe N., Okada S., Emfietzoglou D., Kyriakou I., Murakami K., Sasaki T., Tran H., Guatelli S., Ivantchenko V.N. An implementation of discrete electron transport models for gold in the Geant4 simulation toolkit. Journal of Applied Physics 120:244901, 7pp (2016)

 

105.    Nikitaki Z., Nikolov V., Mavragani I.V., Mladenov E., Mangelis A., Laskaratou D.A., Fragkoulis G.I., Hellweg C.E., Lobachevsky P.N., Martin O.A., Emfietzoglou D., Hatzi V.I., Terzoudi G.I., Iliakis G., and Georgakilas A.G., Measurement of complex DNA damage induction and repair in human cellular systems after exposure to ionizing radiations of varying LET. Free Radical Research 50:S64-S78 (2016).

 

104.    Nikitaki Z., Nikolov V., Mavragani I.V., Plante I., Emfietzoglou D., Iliakis G., Georgakilas A.G. Non-DSB clustered DNA lesions. Does theory colocalize with the experiment? Radiation Physics and Chemistry 128:26-35 (2016)

 

103.     Nikjoo H., Taleei R., Liamsuwan T., Liljequist D., Emfietzoglou D., Perspectives in radiation biophysics: From radiation track structure simulation to mechanistic models of DNA damage and repair. Radiation Physics and Chemistry 128:3-10 (2016)

 

102.    Nikjoo H., Emfietzoglou D., Liamsuwan T., Taleei R., Liljequist D., Uehara S. Radiation track, DNA damage and response. Reports on Progress in Physics 79:116601, 55pp (2016)

 

101.    Sefl M., Kyriakou I., Emfietzoglou D. Impact of cell repopulation and radionuclide uptake phase on cell survival. Medical Physics 43:2715-2720 (2016)

 

100.    Sefl M., Incerti S., Papamichael G., Emfietzoglou D. Calculation of cellular S-values using Geant4-DNA: The effect of cell geometry. Applied Radiation and Isotopes 104:113-123 (2015)

 

99.      Abril I., de Vera P., Garcia-Molina R., Kyriakou I., Emfietzoglou D.  Lateral spread of dose distribution by therapeutic proton beams in liquid water. Nuclear Instruments and Methods B: Beam Interactions with Materials and Atoms 352:176-180 (2015)

 

98.      Garcia-Molina R., Abril I., de Vera P., Kyriakou I., Emfietzoglou D. A study of the energy deposition profile of proton beams in materials of hadron therapeutic interest. Applied Radiation and Isotopes 83:109-114 (2014)

 

97.      Emfietzoglou D., Kyriakou I., Abril I., Garcia-Molina R. Erratum: “The effect of static many-body local-field corrections to inelastic electron scattering in condensed media” Journal of Applied Physics 115:139901, 2pp (2014)

 

96.      Emfietzoglou D., Kyriakou I., Abril I., Garcia-Molina R., Nikjoo H. Inelastic cross sections for low-energy electrons in liquid water: exchange and correlation effects. Radiation Research 180:499-513 (2013)

 

95.      Emfietzoglou D., Kyriakou I., Abril I., Garcia-Molina R. The effect of static many-body local-field corrections to inelastic electron scattering in condensed media. Journal of Applied Physics 114:144907, 10pp (2013)

 

94.      Kyriakou I., Emfietzoglou D., Nojeh A., Moscovitch M. Monte Carlo study of electron beam penetration and backscattering in multi-walled carbon nanotube materials: the effect of different scattering models. Journal of Applied Physics 113:084303, 11pp (2013)

 

93.      Abril I., Garcia-Molina R., de Vera P., Kyriakou I., Emfietzoglou D. Inelastic collisions of energetic protons in biological media. Advances in Quantum Chemistry 65:129-164 (2013)

 

92.      Bousis C., Emfietzoglou D., Nikjoo H. Calculations of absorbed fractions in small water spheres for low-energy monoenergetic electrons and the Auger-emitting radionuclides 123I and 125I. International Journal of Radiation Biology 88:916-921 (2012)

 

91.      Bousis C., Emfietzoglou D., Nikjoo H. Monte Carlo single-cell dosimetry of I-131, I-125 and I-123 for targeted radioimmunotherapy of B-cell Lymphoma. International Journal of Radiation Biology 88:908-915 (2012)

 

90.      Liamsuwan T., Emfietzoglou D., Uehara S., Nikjoo H.  Microdosimetry of low-energy electrons. International Journal of Radiation Biology 88:899-907 (2012)

 

89.      Kalantzis G., Emfietzoglou D., Hadjidoukas P. A unified spatio-temporal parallelization framework for accelerated Monte Carlo radiobiological modeling of electron tracks and subsequent radiation chemistry. Computer Physics Communications 183:1683-1695 (2012)

 

88.      Horowitz Y., Sibony D., Oster L., Livingstone J., Guatelli S., Rosenfeld A., Emfietzoglou D., Bilski P., Obryk B. Alpha particle and proton relative thermoluminescence efficiencies in LiF:Mg,Cu,P: Is track structure theory up to the task ? Radiation Protection Dosimetry 150:359-374 (2012)

 

87.      Emfietzoglou D., Kyriakou I., Garcia-Molina R., Abril I., Kostarelos K. Quasi first-principles Monte Carlo modeling of energy dissipation by low-energy electron beams in multi-walled carbon nanotube materials. Applied Physics Letters 100:093113, 5pp (2012)

 

86.      Saikiran V., Pathak A.P., Srinivasa Rao N., Devaraju G., Debgupta J., Pillai V.K, Kyriakou I., Emfietzoglou D. SHI irradiation induced effects in functionalized MWCNTs. Radiation Effects and Defects in Solids 167:569-576 (2012)

 

85.      Emfietzoglou D., Kyriakou I., Abril I., Garcia-Molina R., Nikjoo H. Inelastic scattering of low energy electrons in liquid water computed from optical data models of the Bethe surface. International Journal of Radiation Biology 88:22-28 (2012)

 

84.      Garcia-Molina R., Abril I., Heredia-Avalos S., Kyriakou I., Emfietzoglou D. A combined Molecular Dynamics and Monte Carlo simulation of the spatial distribution of energy deposition by proton beams in liquid water. Physics in Medicine and Biology 56:6475-6493 (2011)

 

83.      Kyriakou I., Emfietzoglou D., Garcia-Molina R., Abril I., Kostarelos K. Simple model of bulk and surface excitation effects to inelastic scattering in low-energy electron beam irradiation of multi-walled carbon nanotubes. Journal of Applied Physics 110:054304, 12pp (2011)

 

82.       Bousis C., Emfietzoglou D., Hadjidoukas P., Nikjoo H., Pathak A. Monte Carlo calculations of low-energy electron dose-point-kernels

in water using different stopping power approximations. Nuclear Instruments and Methods B: Beam Interactions with Materials and Atoms 269:1650-1654 (2011)

 

81.      Abril I., Garcia-Molina R., Denton C.D., Kyriakou I., Emfietzoglou D. Energy loss of H and He beams in DNA: calculations based on a realistic energy loss function of the target. Radiation Research 175:247-255 (2011)

 

80.      Liamsuwan T., Uehara S., Emfietzoglou D., Nikjoo H.  Physical and biophysical properties of proton tracks of energies 1 keV to 300 MeV in water. International Journal of Radiation Biology 87:141-160 (2011)

 

79.      Liamsuwan T., Uehara S., Emfietzoglou D., Nikjoo H.  A model for carbon ion interactions in water using the classical trajectory Monte Carlo method. Radiation Protection Dosimetry 143:152-155 (2011)

 

78.      Nikjoo H., Uehara S., Emfietzoglou D., Pinsky L. A database of frequency distributions of energy depositions in small-size targets by electrons and ions. Radiation Protection Dosimetry 143:145-151 (2011)

 

77.      Emfietzoglou D., Kyriakou I., Garcia-Molina R., Abril I., Kostarelos K. Analytic expressions for the inelastic scattering and energy loss of electron and proton beams in carbon nanotubes. Journal of Applied Physics 108:054312, 5pp (2010)

 

76.      Bousis C., Emfietzoglou D., Hadjidoukas P., Nikjoo H. Monte Carlo single-cell dosimetry of Auger-electron emitting radionuclides. Physics in Medicine and Biology 55:2555-2572 (2010)

 

75.      Kyriakou I., Celedón C., Segura R., Emfietzoglou D., Vargas P., Valdés J.E., Abril I., Denton C.D., Kostarelos K., Garcia-Molina R. Energy loss of protons in carbon nanotubes: experiments and calculations. Nuclear Instruments and Methods B: Beam Interactions with Materials and Atoms 268:1781-1785 (2010)

 

74.      Abril I., Denton C.D., de Vera P., Kyriakou I., Emfietzoglou D., Garcia-Molina R., Effect of the Bethe surface description on the electronic excitations induced by energetic proton beams in liquid water and DNA. Nuclear Instruments and Methods B: Beam Interactions with Materials and Atoms 268:1763-1767 (2010)

 

73.      Sathish N., Kyriakou, I., Emfietzoglou D., Pathak A.P., Stopping power of GaAs for swift protons: dielectric function and optical-data model calculations. Nuclear Instruments and Methods B: Beam Interactions with Materials and Atoms 268: 1723-1726 (2010)

 

72.      Hadjidoukas P., Bousis C., Emfietzoglou D. Parallelization of a Monte-Carlo particle transport simulation code. Computer Physics Communications 181:928-936 (2010)

 

71.      Bousis C., Emfietzoglou D., Hadjidoukas P., Nikjoo H. A Monte Carlo study of cellular S-factors for 1 keV to 1 MeV electrons. Physics in Medicine and Biology 54:5023-5038 (2009)

 

70.      Kyriakou I., Emfietzoglou D., Garcia-Molina R., Abril I., Kostarelos K. Electron inelastic mean free path for carbon nanotubes from optical data. Applied Physics Letters 94:263113, 3pp (2009)

 

69.      Garcia-Molina R., Abril I., Denton C.D., Heredia-Avalos S., Kyriakou I., Emfietzoglou D. Calculated depth-dose distributions for H+ and He+ beams in liquid water. Nuclear Instruments and Methods B: Beam Interactions with Materials and Atoms 267:2647-2652 (2009)

 

68.      Emfietzoglou D., Garcia-Molina R., Kyriakou I., Abril I., Nikjoo H. A dielectric response study of the electronic stopping power of liquid water for energetic protons and a new I-value for water. Physics in Medicine and Biology 54:3451-3472 (2009)

 

67.      Bousis C., Emfietzoglou D., Nikjoo H., Hadjidoukas P., Pathak A. The effects of energy-loss straggling and elastic-scattering models on Monte Carlo calculations of dose distribution functions for 10 keV to 1 MeV incident electrons in water. Nuclear Instruments and Methods B: Beam Interactions with Materials and Atoms 267:1725-1732 (2009)

 

66.      Emfietzoglou D., Kyriakou I., Abril I., Garcia-Molina R., Petsalakis I.D., Nikjoo H., Pathak A. Electron inelastic mean free paths in biological matter based on dielectric theory and local-field corrections. Nuclear Instruments and Methods B: Beam Interactions with Materials and Atoms 267:45-52 (2009)

 

65.      Nikjoo H., Emfietzoglou D., Charlton D.E. The Auger effect in physical and biological research. International Journal of Radiation Biology 84:1011-1026 (2008)

 

64.      Emfietzoglou D., Kostarelos K., Hadjidoukas P., Bousis C., Fotopoulos A., Pathak A., Nikjoo H. Subcellular S-values for low energy electrons: A comparison of Monte Carlo simulations and continuous slowing down calculations. International Journal of Radiation Biology 84:1034-1044 (2008)

 

63.      Nikjoo H., Emfietzoglou D., Watanabe R., Uehara S. Can Monte Carlo track structure codes reveal reaction mechanism in DNA damage and improve Radiation Therapy? Radiation Physics and Chemistry 77:1270-1279 (2008)

 

62.      Nikjoo Η. Uehara S, Emfietzoglou D., Brahme A. Heavy charged particles in radiation biology and biophysics. New Journal of Physics 10:075006, 28pp (2008)

 

61.      Bousis C., Emfietzoglou D., Hadjidoukas P., Nikjoo H. A Monte Carlo study of absorbed dose distributions in both the vapor and liquid phases of water by intermediate energy electrons based on different condensed-history transport schemes. Physics in Medicine and Biology 53:3739-3761 (2008)

 

60.      Emfietzoglou D., Abril I., Garcia-Molina R., Petsalakis I.D., Nikjoo H., Kyriakou I., Pathak A. Semi-empirical dielectric descriptions of the Bethe surface of the valence bands of condensed water. Nuclear Instruments and Methods B: Beam Interactions with Materials and Atoms 266:1154-1161 (2008)

 

59.      Bousis C., Emfietzoglou D., Hadjidoukas P., Nikjoo H., Pathak A. Electron ionization cross section calculations for liquid water at high impact energies. Nuclear Instruments and Methods B: Beam Interactions with Materials and Atoms 266:1185-1192 (2008)

 

58.      Pathak A.P., Sathish N., Dhamodaran S., Emfietzoglou D. Study of GaAs and GaN based heterostructure surfaces and interfaces using ion beams and other complementary techniques. Vacuum 82:911-921 (2008)

 

57.      Lacerda L., Soundararajan A., Pastorin G., Al-Jamar K., Turton J., Frederik P., Herrero M.A., Li S., Bao A., Emfietzoglou D., Mather S., Phillips W.T., Prato M., Goins B., Kostarelos K. Dynamic Imaging of functionalized multi-walled carbon nanotube systemic circulation & urinary excretion. Advanced Materials 20:225-230 (2008)

 

56.      Emfietzoglou D., Nikjoo H., Pathak A. Electronic stopping power of liquid water for protons down to the Bragg peak. Radiation Protection Dosimetry 126:97-100 (2007)

 

55.      Emfietzoglou D., Papamichael G., Pathak A., Fotopoulos A., Nikjoo H. Monte Carlo study of energy deposition by heavy charged-particles in sub-cellular volumes. Radiation Protection Dosimetry 126 :457-462 (2007)

 

54.      Hindorf C., Emfietzoglou D., Linden O., Bousis C., Fotopoulos A., Kostarelos K., Flux G. Single cell dosimetry for radioimmunotherapy of B-cell lymphoma patients with special reference to leukaemic spread. Cancer Biotherapy and Radiopharmaceuticals 22:357-366 (2007)

 

53.      Dhamodaran S, Pathak A.P., Avasthi D.K., Srinivasan T., Muralidharan R. Emfietzoglou D. Surface Modification of InGaAs/GaAs Heterostructures by Swift Heavy Ion Irradiation. Nuclear Instruments and Methods B: Beam Interactions with Materials and Atoms 257:301-306 (2007)

 

52.      Emfietzoglou D., Nikjoo H., Pathak A., Sathish N. A comparison of secondary electron spectra from proton-impact ionization on water in the liquid and solid phases. Nuclear Instruments and Methods B: Beam Interactions with Materials and Atoms 257:609-613 (2007)

 

51.      Emfietzoglou D., Nikjoo H., Petsalakis I.D., Pathak A. A consistent dielectric response model for water ice over the whole energy-momentum plane. Nuclear Instruments and Methods B: Beam Interactions with Materials and Atoms 256:141-147 (2007)  

 

50.      George J., Pathak A., Emfietzoglou D. Quantum calculations for the effects of  dislocations on channeling and channeling radiation. Nuclear Instruments and Methods B: Beam Interactions with Materials and Atoms 256:148-152 (2007)

 

49.      Emfietzoglou D., Bousis C., Hindorf C., Fotopoulos A., Pathak, Kostarelos K. A Monte Carlo study of energy deposition at the sub-cellular level for application to targeted radionuclide therapy with low-energy electron emitters. Nuclear Instruments and Methods B: Beam Interactions with Materials and Atoms 256:547-553 (2007)

 

48.      Dhamodaran S., Sathish N., Pathak A.P., Avasthi D.K., Muralidharan R., Sundaravel B., Nair K.G.M., Sridhara Rao D.V., Muraleedharan K., Emfietzoglou D. Ion beam analysis of defects and strain in heavy ion irradiated InGaAs/GaAs heterostructures. Nuclear Instruments and Methods B: Beam Interactions with Materials and Atoms 254:283-288 (2007)

 

47.      Emfietzoglou D., Nikjoo H. Accurate electron inelastic cross sections and stopping powers for liquid water over the 0.1-10 keV range based on an improved dielectric description of the Bethe surface. Radiation Research 167:110-120 (2007)

 

46.      Emfietzoglou D., Nikjoo H., Pathak A. A comparative study of dielectric response function models for liquid water. Radiation Protection Dosimetry 122 :61-65 (2006)

 

45.      Nikjoo H., Uehara S., Emfietzoglou D., Cucinotta F.A. Monte Carlo track structure codes in radiation research – A review. Radiation Measurement 41:1052-1074 (2006)

 

44.      Phillips G.W., Span J., Bogard J.S., VoDinh T., Emfietzoglou D., Devine R., Moscovitch M. Neutron spectrometry using CR-39 track etch detectors. Radiation Protection Dosimetry 120:457-460 (2006)

 

43.     Emfietzoglou D., Papamichael G., Karava K., Androulidakis I., Pathak A., Phillips G.W., Moscovitch M., Kostarelos K. A Monte-Carlo code for the detailed simulation of electron and light-ion tracks in condensed matter. Radiation Protection Dosimetry 119:491-496 (2006)

 

42.      Berillis P., Emfietzoglou D., Tzaphlidou M. Collagen fibril diameter in relation to bone site and to calcium/phosphorus ratio. TheScientificWorldJournal 6:1109-1113 (2006)

 

41.      Dhamodaran S., Sathish N., Pathak A., Khan S.A., Avasthi D.K., Srinivasan T., Muralidharan R., Kesavamoorthy R., Emfietzoglou D. Raman and AFM studies of swift heavy ion irradiated InGaAs/GaAs heterostructures. Journal of Physics: Condensed Matter 18:4135-4142 (2006) 

 

40.      Emfietzoglou D., Nikjoo H., Pathak A. Electronic cross sections for proton transport in liquid water based on optical-data models. Nuclear Instruments and Methods B: Beam Interactions with Materials and Atoms 249:26-28 (2006)

 

39.      Emfietzoglou D., Nikjoo H. Papamichael G., Pathak A. Proton beam profiling in soft biological matter by detailed Monte Carlo simulation. Nuclear Instruments and Methods B: Beam Interactions with Materials and Atoms 249:670-672 (2006)

 

38.      Emfietzoglou D., Paganetti H., Papamichael G., Pathak A. Monte Carlo calculation of nanoscale dosimetric distributions of MeV proton tracks with secondary electron transport. Nuclear Instruments and Methods B: Beam Interactions with Materials and Atoms 245:80-84 (2006)

 

37.       Emfietzoglou D., Pathak A., Papamichael G., Kostarelos K., Dhamodaran S., Sathish N., Moscovitch M. A study on the electronic stopping of protons in soft biological matter. Nuclear Instruments and Methods B: Beam Interactions with Materials and Atoms 242:55-60 (2006)

 

36.      Dhamodaran S., Sathish N., Pathak A. Nageswara Rao S.V.S., Siddiqui A.M., Khan S.A., Avasthi D.K., Srinivasan D.K., Muralidharan R., Muntele C., Ila D., Emfietzoglou D. Ion beam irradiation and characterization of GaAs based hetero-structures. Nuclear Instruments and Methods B: Beam Interactions with Materials and Atoms 242:538-541 (2006)

 

35.      Emfietzoglou D., Cucinotta F.A., Nikjoo H. A complete dielectric response model for liquid water – A solution of the Bethe ridge problem. Radiation Research 164:202-211 (2005)

 

34.      Hindorf C., Emfietzoglou D., Linden O., Kostarelos K., Strand S-E. Internal microdosimetry for single cells in radioimmunotherapy of B-cell lymphoma. Cancer Biotherapy and Radiopharmaceuticals 20:224-230 (2005)

 

33.      Kostarelos K., Emfietzoglou D., Papakostas A., Yang W-H., Ballangrud A., Sgouros G. Engineering lipid vesicles of enhanced intratumoral transport capabilities: correlating liposome characteristics with penetration into human prostate tumor spheroids. Journal of Liposome Research 15:15-27 (2005)

 

32.       Dhamodaran S., Sathish N., Rajam A., Pathak A., Prakash L., Nageswara Rao S.V.S., Raghav Rao V., Emfietzoglou D. Dechanneling of electrons by stacking faults – a model quantum mechanical calculation. Nuclear Instruments and Methods B: Beam Interactions with Materials and Atoms 230:100-105 (2005)

 

31.      Emfietzoglou D., Pathak A., Moscovitch M. Modeling the energy and momentum dependent loss function of the valence shells of liquid water. Nuclear Instruments and Methods B: Beam Interactions with Materials and Atoms 230:77-84 (2005)

 

30.      Emfietzoglou D., Papamichael G., Androulidakis I., Karava K., Kostarelos K., Pathak A., Moscovitch M. A Monte-Carlo study of sub-keV electron transport in water: the influence of the condensed-phase. Nuclear Instruments and Methods B: Beam Interactions with Materials and Atoms 228:341-348 (2005)

 

29.      Emfietzoglou D., Kostarelos K., Papakostas A., Yang W-H., Ballangrud A., Song H., Sgouros G. Liposome-mediated radiotherapeutics within avascular tumor spheroids: comparative dosimetry study for various radionuclides, liposome systems and a targeting antibody. Journal of Nuclear Medicine 46:89-97 (2005)

 

28.      Akkerman A., Barak J., Emfietzoglou D. Ion and electron track-structure and its effects in silicon: model and calculations. Nuclear Instruments and Methods B: Beam Interactions with Materials and Atoms 227:319-336 (2005)

 

27.      Emfietzoglou D., Nikjoo H. The effect of model approximations on single-collision distributions of low-energy electrons in liquid water. Radiation Research 163:98-111 (2005)

 

26.      Kostarelos K., Emfietzoglou D., Tadros T.F. Light-sensitive fusion between polymer-coated liposomes following physical anchoring of di-block copolymers onto lipid bilayers by self-assembly. Faraday Discussions 128:379-388 (2005).

 

25.      Emfietzoglou D., Akkerman A., Barak J. New Monte-Carlo calculations of charged particles track-structure in silicon. IEEE Transactions on Nuclear Science 51:2872-2879 (2004)

 

24.      Kostarelos K., Emfietzoglou D., Papakostas A., Yang W-H , Ballangrud A., Sgouros G. Binding and interstitial penetration of liposomes within avascular tumor spheroids. International Journal of Cancer 112:713-721 (2004)

 

23.      Emfietzoglou D., Karava K., Papamichael G., Moscovitch M.  Monte-Carlo calculations of radial dose and restricted-LET for protons in water. Radiation Protection Dosimetry 110:871-879 (2004)

 

22.      Emfietzoglou D., Moscovitch M, Pathak A. Inelastic cross-sections of energetic protons in liquid water calculated by model dielectric functions and optical data. Nuclear Instruments and Methods B: Beam Interactions with Materials and Atoms 212:101-109 (2003)

 

21.      Emfietzoglou D., Karava K., Papamichael G., Moscovitch M. Monte-Carlo simulation of the energy-loss of low-energy electrons in liquid water. Physics in Medicine and Biology 48:2355-2371 (2003)

 

20.      Emfietzoglou D. and Moscovitch M. Secondary electron spectra for fast proton impact on gaseous and liquid water. Nuclear Instruments and Methods B: Beam Interactions with Materials and Atoms 209:239-245 (2003)

 

19.      Emfietzoglou D. Inelastic Cross-sections for electron transport in liquid water: a comparison of dielectric models. Radiation Physics and Chemistry 66:373-385 (2003)

 

18.      Moscovitch M., Phillips G.W., Cullum B.M., Mobley J., Bogard J.S., Emfietzoglou D., Vo-Dinh T. Radiation dosimetry using three-dimensional optical random access memories. Radiation Protection Dosimetry 101:17-22 (2002)

 

17.      Emfietzoglou D. Modeling the energy-loss mechanism of charged particles in organic solids. Radiation Protection Dosimetry 100:153-158 (2002)

 

16.      Emfietzoglou D. and Moscovitch M. Inelastic collision characteristics of electrons in liquid water. Nuclear Instruments and Methods B: Beam Interactions with Materials and Atoms 193:71-78 (2002)

 

15.      Emfietzoglou D. Semi-empirical inelastic cross-sections for electron transport in liquid water. Radiation Protection Dosimetry 99:39-46 (2002)

 

14.      Emfietzoglou D., Kostarelos K., Sgouros G. An analytic dosimetry study for the use of radionuclide-liposome conjugates in internal radiotherapy. Journal of Nuclear Medicine 42:499-504 (2001)

 

13.      Emfietzoglou D., Papamichael G., Moscovitch M. Charged particle interactions in water: cross sections and simulations. Radiation Physics and Chemistry 61:597-598 (2001)

 

12.      Emfietzoglou D., Papamichael G., Moscovitch M. Monte Carlo simulation of charged particle transport in biomatter. Physica Medica 17:113-114 (2001)

 

11.      Kostarelos K. and Emfietzoglou D. Tissue dosimetry of liposome-radionuclide complexes for internal radiotherapy: toward liposome-targeted therapeutic radiopharmaceuticals. Anticancer Research 20:3339-3346 (2000)

 

10.      Emfietzoglou D., Papamichael G., Kostarelos K., Moscovitch M. A Monte-Carlo track structure code for electrons (~10 eV-10 KeV) and protons (~0.3-10 MeV) in water: partitioning of energy and collision events. Physics in Medicine and Biology 45:3171-3194 (2000)

 

9.        Emfietzoglou D., Papamichael G., Moscovitch M. An event-by-event computer simulation of interactions of energetic charged-particles and all their secondary electrons in water. Journal of Physics D: Applied Physics 33:932-944 (2000)

 

8.        Kostarelos K. and Emfietzoglou D. Liposomes as carriers of radionuclides: from imaging to therapy (REVIEW). Journal of Liposome Research 9:429-460 (1999)

 

7.            Kostarelos K., Emfietzoglou D., Stamatelou M. Liposome-mediated delivery of radionuclides to tumor models for cancer radiotherapy: a quantitative analysis. Journal of Liposome Research 9:407-424 (1999)

 

6.        jkljlllllluuEmfietzoglou D. and Moscovitch M. A potential application to the study of microscopic energy deposition in a solid by means of heavy charged-particle induced photochromic alterations in a tissue-equivalent matrix. Physics in Medicine and Biology 44:207-221 (1999)

 

5.        Moscovitch M. and Emfietzoglou D. Simulation of radiation effects on three-dimensional computer optical memories. Journal of Applied Physics 81:58-69 (1997)

 

4.        Otero G., Avila M.A., Pena L., Emfietzoglou D., Cansado J., Popescu G.F., Notario V. Altered processing of precursor transcripts and increased levels of the subunit I of mitochondrial cytochrome c oxidase in syrian hamster fetal cells initiated with ionizing radiation. Carcinogenesis 18:1569-1575 (1997)

 

3.        Otero G., Avila M.A., Emfietzoglou D., Clerch L.B., Massaro D., Notario V. Increased manganese superoxide dismutase activity, protein and mRNA and concurrent induction of tumor necrosis factor a in radiation initiated syrian hamster cells. Molecular Carcinogenesis 17:175-180 (1996)

 

2.        Emfietzoglou D. and Moscovitch M. Phenomenological study of light-induced effects in a-Al2O3:C. Radiation Protection Dosimetry 65:259-262 (1996)

 

1.        Akselrod M., McKeever S.W.S., Moscovitch M., Emfietzoglou D., Durham J.S., Soares C.G. A thin layer Al2O3:C beta TL detector. Radiation Protection Dosimetry 66:105-110 (1996)

 

 

 

OTHER PUBLICATIONS

 

Nikjoo H., Uehara S., Emfietzoglou D. 2012. Interaction of Radiation with Matter. (CRC Press Taylor & Francis Group, Boca Raton, FL. 2012)

 

Features

 

• Includes the relevant atomic physics background 

• Describes the interactions of photons, electrons, and heavy charged particles with matter 

• Covers modeling and simulation techniques

• Highlights applications in medical/health physics and radiation biology

• Draws on the authors’ many years of teaching radiation interaction and microdosimetry courses

• Provides numerous references at the end of each chapter as well as exercises at the back of the book.

 

Solutions manual available with qualifying course adoption

 

Summary

 

Interaction of Radiation with Matter focuses on the physics of the interactions of ionizing radiation in living matter and the Monte Carlo simulation of radiation tracks. Clearly progressing from an elementary level to the state of the art, the text explores the classical physics of track description as well as modern aspects based on condensed matter physics.

 

The first section of the book discusses the fundamentals of the radiation field. In the second section, the authors describe the cross sections for electrons and heavy ions—the most important information needed for simulating radiation track at the molecular level. The third section details the inelastic scattering and energy loss of charged particles in condensed media, particularly liquid water. The final section contains a large number of questions and problems to reinforce learning.

 

Designed for radiation interaction courses, this textbook is the ideal platform for teaching students in medical/health physics and nuclear engineering. It gives students a solid grounding in the physical understanding of radiation track structure in living matter, enabling them to pursue further work in radiological physics and radiation dosimetry.

 

 

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