RETURN

(j) Supervision of M.Sc degrees in Bioinorganic Chemistry

Within the framework of the graduate programme “BIOINORGANIC CHEMISTRY”,

which I coordinated and I have been the chairman since 1998,until 2008, the M.Sc thesis of

several students, that worked under my supervision, were approved,with perhaps the most

important .

1. ALEXANDRA MYARI, “Interactions of Metal Ions with Small Peptides of Histidine, Models of the

Active Center of the Enzyme Superoxide Dismutase (SOD)”, July 2000.

2. CHRYSOULA VARTZOUMA, “Enzymic Action of Thiamine and Its Derivatives,

Immobilized on Inorganic Materials”, March 2002.

3. DIMITRIOS KOSTAKIS, “Synthesis and Characterization of Complex Compounds of

Trivalent Lanthanide Ions with Modified Polyaminocarboxylic Acids”, March 2002.

4. MARIA PETROUTSA, «Multiple drug resistance of As(III) compounds in cancer cells

of the GLC-4 series».,March 2003.

5. CHRISTOS CHASAPIS, «Synthesis, Characterization and Spectroscopic Study of new

Organotin(IV) compounds with the aminoacid cysteine».March 2003.

The graduate programme “BIOINORGANIC CHEMISTRY”, will soon restart with the

new name “Biological Inorganic Chemistry” and with the participation of the Departments of

Chemistry of the Universities of Ioannina,Thessaloniki,Patras,Crete,Cyprus,Athens

The number of graduates,until today, May 2015, were more than 150,with M.Sc

and Ph.d degrees with 500 estimated publications in journals of the discipline.

(k)Doctoral Thesis

I have been in the three members committee of many Doctoral Thesis.Examples:.

1. C. VARTZOUMA «Enzymatic activity and thiamine derivatives, immobilized in inorganic

materials » University of Ioannina (2006).

2. G KOSTAKIS Synthesis, characterization and properties of polymers with bioogical related

ligands University of Ioannina (2006).

3.Κ.ΑΝΤONIADIS,"Synthesis,characterization and study of new complex compounds

of Iodine with ligands of possible antithyroid action,like thioamides.Contribution

In the study of the mechanism of action of antithyroid drugs"University of Ioannina

(2005)

4.Μ.XANTHOPOULOU«Applications of thioamides in Biomedicine.Synthesis

Study of new organotin(IV) complex compounds of thioamides with possible

Biological Action.».University of Ioannina (2006).

5. G. GORBAN,”Synthesis,characterization and study of new complex

compounds of di-iodine or/and iron,with ligands acting possibly as antithyroid

Drugs.Possible implication of the new compounds in the mechanism of synthesis

of thyroid drugs».Παν/μιο Ιωαννίνων (2006)

6. ΙΒRAHIM OZTURK ,”Synthesis,characterization and study of new complex

Compounds of antimony with thioamide ligands with

biological action”.University of Ioannina (2009).

7. Κ TRIANTAFILIDI, "Complexes of Ru (II) with poly-pyridine digands conjugated with amino

acids. Synthesis, characterization and study of their interactions with DNA and oligonucleotides»

University of Ioannina (2009).

(l) Supervision of Doctoral thesis

(Supervising Professor)

1. M.PLYTZANOPOULOS, "Complex Compounds of 2-benzoylpyridine with 1^st row

transition metals", University of Athens (1978).

2. I.MARKOPOULOS, "Reactions of Pt(II) and Pd(II) with thiamine, its phosphate

esters and their deuterated derivatives", University of Athens (1981).

3. D.KOVALA-DEMERTZI, "Complexes of o-aminobenzylamine with Cu(II), Ni(II)

and Co(II)", University of Ioannina (1983).

4. V.THEODOROU-KASSIOUMI, "Reactions of K₂PtCl₄ with S-alkyl and S-aralkyl

derivatives of cysteine", University of Athens (1984).

5. S.KASSELOURI, "Mixed Complexes of Pd(II) with nucleosides, amino acids and

peptides", University of Ioannina (1989).

6. A.GAROUFIS, "Mixed Complexes of Pt(II) with amino acids and nucleo-

sides", University of Ioannina (1989).

7. M.LOULOUDI, "Synthesis and Characterization of Bivalent Metal Complexes of

the "Active Aldehyde" Derivatives of Thiamine.Role of the Bivalent Metal

Ions in the Enzymatic Action of Thiamine, University of Ioannina (1992).

8. A.IAKOVIDIS, "Ternary Complexes of Pt(II) and Pt(IV) with aminoacids and

nucleobases", University of Ioannina (1992).

9. V.ALETRAS, "Ternary Complexes of cis- and trans-[NH₃)₂PtCl₂ with nucleobases,

aminoacids and peptides", University of Ioannina (1995).

10.G.KALKANIS, "Complexes of the transition metals Mn²⁺, Ni²⁺, Cu²⁺, Co²⁺, Fe²⁺

and of Zn²⁺ with Schiff bases deriving form the condensation of 2-pyridinaldehyde

and (2-acetyl-pyridine) with 1,2-phenylenediamine", University of Ioannina (1996).

11.S.GOURBATSIS, "Preparation and study of monomeric complex compounds of

Fe(III), Co(II), Ni(II), Cu(II), Pd(II) and Pt(II) with terdentate Schiff bases. Contribution

to the polymerization of the monomeric structural units with the use of bidentate

bridging organic ligands", University of Ioannina (1996).

12.P.TSIVERIOTIS, "A Study of the Interactions of Small Peptides Containing Histidine

with Complex Ions of Pt(II) and Pd(II)", University of Ioannina (1997).

13.A.PHILIPPOPOULOS, "Synthesis and Characterization of New Organometallic

Complexes of Rh and Co with the Ligand, C₅H₅-(CH₂)₂N(CH₃)₂ a Cyclopentadienyl

Derivatives, with Possible Catalytic and Antitumor Properties", University of

Ioannina (1997).

14.E.KATSAROU, "Synthesis and Study of Ternary Systems of Pt(II)-Nucleosides and

Amino acids-Peptides. ¹H NMR Study of the Interaction of Pd(II)-Dipeptides

complexes with the Oligonucleotide d(CGCGAATTCGCG)₂", University of Ioannina

(1998).

15.K.DODI, "Complex Compounds of “active aldehyde” Derivatives of Thiamine and Its

Phosphate Esters with Elements of Group II_B. Rôle of Metal Ions in the Enzymatic Action

of Thiamine”, University of Ioannina (2000).

16.G.MALANDRINOS, “Interaction of Zn²⁺, Cd²⁺, Cu²⁺ with 2-(α-Hydroxy-ethyl)thiamine

pyrophosphate (HETPP) and thiamine pyrophosphate (TPP). Mechanism of enzymatic

action of thiamine enzymes”, University of Ioannina (2000).

17.M.MYLONAS, “Interaction of the metallic ions Cu²⁺ and Ni²⁺ with peptide models of

histones and nucleotides. Contribution to the study of the mechanism of carcinogenesis

by metallic ions”, University of Ioannina (2003).

18.K.KARYDI, “Synthesis, characterization and study of the interactions of polypyridine

complexes of ruthenium containing NO and coupled aminoacids and peptides”,

University of Ioannina (2005).

19.C.CHASSAPIS, “Structural genomics participating in copper hemeostasis”, University of

Ioannina (2005).

20. M.KATSAROU, “A Study of Genes Expression Related to the Process of “Splicing” and

the Apoptosis Caused by Antitumor Drugs in Leucemia Cell Series. Proteins Expression,

Structural and Biochemical Studies”, University of Ioannina (2005).

21.A.MYARI, “Applications of Peptides in the Study of the Mechanism of Cu(I) transfer from

ATPase in Wilson disease and in the interactions with DNA of the tris-bipyridilic Complexes

Of Ru(II)”, University of Ioannina (2006).

22. P.CHRISTOFIS, “Biophysical and Biochemical Study of Antitumor Complexes of

Platinum”, University of Ioannina (2006).

23.ANA MONICA NUNES,”Study of the mechanism of toxicity and carcinogenicity induced by

metal ions”,University of Ioannina (2009)

24.K.ZAVITSANOS,”Interactions of metal ions Ni(II) and Cu(II) with Histone H2B Peptide

Models”,University of Ioannina (2009).