RETURN

(2) Publications in International Journals

1. N.HADJILIADIS and T.THEOPHANIDES, "Infrared Studies on Complexes of

Platinum with Adenosine and Derivatives", Can.J.Spectry, 16, 135 (1971).

2. N.HADJILIADIS, A.DIOT and T.THEOPHANIDES, "A Quantum Chemical Conforma-

tional Analysis of the Ethylenediamine Molecule", Can.J.Chem., 50, 1005 (1972).

3. N.HADJILIADIS, P.KOUROUNAKIS and T.THEOPHANIDES,"Interactions of Pt(II)

with Adenosine and its Acetyl Derivatives", Inorg.Chim.Acta, 7, 226 (1973).

4. N.HADJILIADIS and T.THEOPHANIDES, "LCAO-EHMO Study of Rotational

Isomerism in 1,2-Disubstituted Ethanes", Chim.Chron.(New Series), 2, 37 (1973).

5. A.TERZIS, N.HADJILIADIS, R.RIVEST and T.THEOPHANIDES,"X-Ray Crystal Structure

of a Platinum-9-Methyladenine Complex",Inorg.Chim.Acta, 12, L5 (1975).

6. N.HADJILIADIS and T.THEOPHANIDES, "Synthesis of 6-Thiopurine Riboside

Complexes of Pt(II)", Inorg.Chim.Acta, 15,167 (1975).

7. N.HADJILIADIS and T.THEOPHANIDES, "Applications of Quantum mechanics in

Chemistry", Chim.Chron. (General Edition), 40, 11(1975).

8. N.HADJILIADIS and T.THEOPHANIDES, "Platinum Purine Nucleosides I. Interaction

of K₂PtX₄ (X=Cl,Br) with Adenosine, Triacetyladenosine, Adenosine-1-oxide

and 9-Methyladenine", Inorg.Chim.Acta, 16, 67 (1976).

9. N.HADJILIADIS and T.THEOPHANIDES, "Platinum Purine Nucleosides II. Interaction

of K₂PtX₄ (X=Cl,Br) with Inosine and Guanosine", Inorg.Chim.Acta, 16, 77 (1976).

10. T.THEOPHANIDES, N.HADJILIADIS, M.BERZOT, N.MANFAIT and L.BERNARD,

"Raman Studies of Platinum-Nucleoside Complexes", J.Raman Spectry, 5, 315 (1976).

11. G.PNEUMATIKAKIS, N.HADJILIADIS and T.THEOPHANIDES, "Palladium Reactions

with Guanosine. Definitive Evidence for O(6)N(7) chelation", Inorg.Chim.Acta,

22, L1 (1977).

12. M.PLYTZANOPOULOS, G.PNEUMATIKAKIS, N.HADJILIADIS and D.KATAKIS,

"First row transition metal complexes with 2-benzoylpyridine", J.Inorg.Nucl.Chem.,

39, 965 (1977).

13. N.HADJILIADIS and T.THEOPHANIDES, "Infrared Studies of Platinum 6-Thio-

purine Riboside Complexes", Can.J.Spectry, 22, 51(1977).

14. N.HADJILIADIS, J.MARKOPOULOS, G.PNEUMATIKAKIS, D.KATAKIS and T.

THEOPHANIDES, "Interaction of Thiamine and its Phosphate Esters with Pt(II) and

Pd(II)", Inorg.Chim.Acta, 25, 21 (1977).

15. N.HADJILIADIS, "IR spectra of 9-Methyladenine, Pt(9-MethyladenineH)Cl₃

and their deuterated derivatives", Chim.Chron., (New Series), 6, 479 (1977).

16. N.HADJILIADIS, J.MARKOPOULOS, G.PNEUMATIKAKIS and D.KATAKIS,

"Interaction of Thiamine and its Phosphate Esters with Pt(II) and Pd(II)",

J.Clin.Hematal.Oncol., 7, 289 (1977) (3rd International Symposium on

Platinum etc. in Cancer Chemother.),Dallas, Texas (USA).

17. N.HADJILIADIS and J.MARKOPOULOS, "Platinum complex compounds in

Cancer Chemotherapy", Chim.Chron. (General Edition), 42, 30 (1977).

18. G.PNEUMATIKAKIS, N.HADJILIADIS and T.THEOPHANIDES, "Complexes of

Inosine, Cytidine and Guanosine with Pd(II)", Inorg.Chem., 17, 915 (1978).

19. N.HADJILIADIS and G.PNEUMATIKAKIS "Compelexes of Pd(II) with nucleosides.

Preparation and properties of the mononucleoside complexes of the type

K[Pd(nucl)Cl₃]", J.Chem.Soc.Dalton Trans., 1691 (1978).

20. G.PNEUMATIKAKIS and N.HADJILIADIS, "Complexes of Cysteine and

Cysteinemethylester with Pd(II) and Pt(II)", J.Inorg.Nucl.Chem., 41, 429 (1979).

21. G.PNEUMATIKAKIS and N.HADJILIADIS, "Interactions of Tetrakis-Μ-

acetatodirhodium(II) with Adenine Nucleosides and Nucleotides", J.Chem.Soc.,

Dalton Trans., 596 (1979).

22. J.MARKOPOULOS, O.MARKOPOULOU and N.HADJILIADIS, "Complexes of Tetra-

hydrothiamine with Pt(II)", Inorg.Chim.Acta, 34, L299 (1979).

23. N.HADJILIADIS and G.PNEUMATIKAKIS, "Complexes of d(+)-Biotin with Pd(II)

and Pt(II)", J.Inorg.Biochem., 10, 215 (1979).

24. M.PLYTZANOPOULOS, G.PNEUMATIKAKIS, N.HADJILIADIS, D.KATAKIS and

V.PAPADOPOULOS, "Complexes of Iron(II), Iron(III) and Manganese(II) with

2-Benzoylpyridine", Chim.Chron., (New Series), 8, 109 (1979).

25. N.HADJILIADIS and G.PNEUMATIKAKIS, "A Study of the Reactions of

CysteinatΤ-methylester platinum(II)-Μ-dichlorocysteinato methylester platinum(II), with

nucleosides",Inorg.Chim.Acta, Bioinorg.Chem.Section, 46, 255 (1980).

26. N.HADJILIADIS, G.PNEUMATIKAKIS and R.BASOSI, "Gold Complexes of Purine

and Pyrimidine Nucleosides", J.Inorg.Biochem., 14, 115 (1981).

27. N.HADJILIADIS and J.MARKOPOULOS, "Reactions of hydrogenated thiamine

derivatives with K₂MX_4, where M is Pd(II) or Pt(II) and X is Cl or Br", J.Chem.Soc.,

Dalton Trans.,1635 (1981).

28. N.HADJILIADIS and J.MARKOPOULOS, "Vitamin B₁", (Isolation, preparation, properties,

mechanism of catalytic action),Chim.Chron. (New Series), 10, 1 (1981).

29. V.THEODOROU, I.PHOTAKI, N.HADJILIADIS, R.W.GELLERT and R.BAU, "Spectro-

scopic Studies and X-Ray Crystal Structure Determination of the Complex

cis-(S-ethylcysteine)platinum(II)dichloride", Inorg.Chim.Acta, 60, 1 (1982).

30. N.HADJILIADIS, G.PNEUMATIKAKIS and S.PARASKEVAS, "Platinum(II) and

Palladium(II) complexes of Inosine, Guanosine, Xanthosine, and their acetyl

derivatives", Chim.Chron. (NewSeries), 11,11 (1982).

31. N.HADJILIADIS, A.YANNOPOULOS and R.BAU, "Complexes of Mercury(II) with

Thiamine", Inorg.Chim.Acta, 69, 109 (1983).

32. D.KOVALA-DEMERTZI, J.M.TSANGARIS and N.HADJILIADIS, "Complexes of

Aminobenzylamines. Part I. Complexes of o-Aminobenzylamine with Copper(II),

Cobalt(II) and Nickel(II)", Trans.Metal.Chem., 8, 140 (1983).

33. M.A.BRUCK, H.J.KORTE, R.BAU, N.HADJILIADIS and B.K.TEO,"EXAFS Analysis

of 6-Mercaptopurine riboside Complexes of Platinum(II) and Palladium(II)",

"Chemistry and Biochemistry of Platinum, Gold and other therapeutic agents",

American Chem.Soc.Symp.Series, editor S.J.Lippard, No 209, 245 (1983).

34. G.H.M.CALIS and N.HADJILIADIS, «Gold(III) and Gold(I) Complexes of purine and

Pyrimidine Nucleosides Studied by IR H¹ NMR and An¹⁹⁷ Mössbauer Spectroscopies»,

Inorg.Chim.Acta, 79, 241 (1983).

35. N.HADJILIADIS,"cis and Trans-dichloropalladium(II)-bis(nucleoside), cis and

trans-bis(nucleosidato)palladium(II) and cis and trans-[bis(nucleoside)

bis(nucleoside)'palladium(II)] dichloride or [tetrakis(nucleoside)palladium(II)]

dichloride", Inorg.Synthesis, Vol.XXIII, ed. S.Kirschner, 51 (1984).

36. G.H.M.CALIS and N.HADJILIADIS, "Structure and Bonding of Gold(I) and Gold(III)

Nucleosides Studied by ¹⁹⁷Au Mossbauer Spectroscopy", Inorg.Chim.Acta, 91,

203 (1984).

37. D.KOVALA-DEMERTZI, J.M.TSANGARIS and N.HADJILIADIS, "Complexes of

Aminobenzylamines Part II. Complexes of o-Aminobenzylamine with Pd(II)

and Pt(II)", Trans.Metal Chem., 9, 77 (1984).

38. A.YANNOPOULOS and N.HADJILIADIS, "Reactions of THTH(Tetrahydro-

thiamine) with HgX₂ (X=Cl,Br,I)",Inorg.Chim.Acta, 92, L23 (1984).

39. J.P.LAUSSAC, R.HARAN et N.HADJILIADIS, "Interaction du Pd⁺² avec le tripeptide

du serum, modulateur de croissance, glycyl-L-histidyl-L-lysine: Etude par

Resonance Magnetique Nucleaire", C.R.Academie des Sciences (Paris),

presentee par Fernand Gallais, t. 300, Serie II, p. 137 (1985).

40. V.THEODOROU and N.HADJILIADIS, "S-Alkyl and S-Alkylaryl Cysteine

Complexes with Platinum(II) and their Interactions with Nucleosides", Polyhedron,

4(7), 1283 (1985).

41. D.KOVALA-DEMERTZI, N.HADJILIADIS and J.M.TSANGARIS,"Complex Compounds of

Cu(II), Ni(II) and Co(II) with aliphatic and aromatic mono and diamines", Chim.Chron. (New

Series), 14, 3 (1985).

42. D.KOVALA-DEMERTZI, N.HADJILIADIS and J.M.TSANGARIS, "Complexes Τf

2',4'-diamino-5(3',4',5'-trimethoxybenzyl)pyrimidine(trimethroprim) with Pt(II),

Rh(II) and Au(III)", Journal of the Less-Common Metals (Precious Metals Section),

115, 1 (1986).

43. N.D.HADJILIADIS, "Platinum Coordination Complexes in Cancer Chemotherapy.

Complexes of Nucleosides with Pt(II) and Pd(II)", "Science and Humanity", Edition

of the Soviet Academy of Sciences, 140 (1987) in Russian and in German.

44. S.KASSELOURI, A.GAROUFIS and N.HADJILIADIS, "Pd(II) and Pt(II) ternary

complexes with nucleosides and amino acids", Inorg.Chim.Acta, 135, L23 (1987).

45. J.P.LAUSSAC, M.PASDELOUP and N.HADJILIADIS, "NMR Studies on Binary

and Ternary Pd(II) Complexes Formed by the Growth-Modulating Tripeptide Glycyl-

histidyllysine and Nucleotides", J.Inorg.Biochem., 30, 227 (1987).

46. A.GAROUFIS, R.HARAN, M.PASDELOUP, J.P.LAUSSAC and N.HADJILIADIS,

"Interaction of cis-Pt(ino)₂Cl₂ with AminoAcids", J.Inorg.Biochem., 31, 65 (1987).

47. N.HADJILIADIS, "Complex Coordination Compounds, in Cancer Chemotherapy.

Nucleoside Complexes of Pt(II) and Pd(II)", Chim.Chron. (General Edition), 52, 148

(1987).

48. A.GAROUFIS, S.KASSELOURI, J.P.LAUSSAC and N.HADJILIADIS, "Ternary

complexes of Pt⁺² and Pd⁺² with ino, guo and aminoacids", 5^th International

Symposium on Platinum etc in Cancer Chemotherapy, Padova, Italy,

657 (1987), editor Marino Nicolini, (Martinus Nijhoff Publishing).

49. I.YAKOVIDIS, G.VARVOUNIS AND N.HADJILIADIS, "Copper(II) Complexes of Thieno-

(2,3-d)pyrimidine derivatives",Inorg.Chim.Acta, Bioinorg.Chem.Section, 151(3),

165 (1988).

50. M.LOULOUDI, D.KOVALA-DEMERTZI and N.HADJILIADIS, "Cobalt(II), Nickel(II),

Copper(II) and Zinc(II) Complexes of Thiazolidine", Bull.Soc.Chim.Belges., 97,

91 (1988).

51. R.BAU, YUN-SOO HYUN, JOHN LIM, HOK-KIN CHOI, A.YANNOPOULOS and

N.HADJILIADIS, "The Crystal Structure of Tetrahydrothiamine and its Co(II)

Complex", Inorg.Chim.Acta, 150, 107 (1988).

52. N.HADJILIADIS, A.YANNOPOULOS, E.DE GRAVE and R.BAU, "Complexes of

tetrahydrothiamine and its phosphate esters withCr(III), Fe(III), Co(II), Ni(II)

and Cu(II)", Bull.Soc.Chim.Belges, 98, 223 (1989).

53. S.WIMMER, P.CASTAN, N.FERDERIGOS, N.HADJILIADIS et J.P.LAUSSAC, "Interac-

tion entre le platine(II) et untetrapeptide modele de la metallothioneine: etude RMN (1D,2D)",

C.R.Academie des Sciences (Paris) presentee par Fernand Gallais, t. 308,

Serie II, 1775 (1989).

54. M.LOULOUDI, A.MICHAILIDIS, J.P.LAUSSAC, R.BAU and N.HADJILIADIS,

"Thiamine active acetaldehyde derivative complexes with II_B bivalent metal ions",

C.R.Academie des Sciences,(Paris), presentee par Fernand Gallais, t. 309, Serie II,

463 (1989).

55. A.IAKOVIDIS, N.HADJILIADIS, H.SCHOLLHORN, U.THEWALT and G.TROTSCHER,

"Interaction of cis-Pt(NH₃)₂Cl₂ with Amino Acids.The Crystal Structures of

cis-[Pt(NH₃)₂(gly)](NO₃), cis-[Pt(NH₃)₂(ala)](NO₃) and cis-[Pt(NH₃)₂(val)](NO₃)",

Inorg.Chim.Acta, 164, 221 (1989).

56. S.KASSELOURI, J.P.LAUSSAC and N.HADJILIADIS, "Trans-Ternary Complexes of

Pd(II) with Nucleosides and Dipeptides. Models for trans-DDP-DNA protein

crosslinks", Inorg.Chim.Acta, 166, 239 (1989).

57. S.KASSELOURI, A.GAROUFIS, M.LAMERA-HADJILIADI and N.HADJILIADIS,

"Binary Complexes of Pd(II) with Peptides and Ternary Complexes of Pd(II) with

Peptides and Nucleosides-Nucleotides", Coord.Chem.Revs., 104, 1 (1990).

58. S.KASSELOURI and N.HADJILIADIS, "Interaction of cis-Pd(guo)₂Cl₂ with Amino

Acids", Inorg.Chim.Acta., 168(1), 15 (1990).

59. F.SCHWARZ, B.LIPPERT, A.IAKOVIDIS and N.HADJILIADIS,"Ternary Complexes of

cis-(NH₃)₂Pt(II) with Model Nucleobases(1-Methylcytosine, 9-Methylguanine)

and N and O Bound Amino Acids(gly,ala)", Inorg.Chim.Acta., 168, 275 (1990).

60. S.GOURBATSIS, S.P.PERLEPES, N.HADJILIADIS and G.KALKANIS,"The

Coordination Chemistry of N,N'-ethylenebis(2-acetylpyridineimine) and N,N'-

ethylenebis(2-benzoylpyridine imine); two potentially tetradentate ligands

containing four nitrogen atoms", Trans.Metal.Chem., 15, 300 (1990).

61. M.LOULOUDI, N.HADJILIADIS, J.A.FENG, S.SUKUMAR and R.BAU,"Interaction of

Zn⁺², Cd⁺² and Hg⁺² with 2-(·-hydroxybenzyl)thiamine and 2-(·-hydroxy-

cyclohexylmethyl)thiamine. The crystal structure of the complex Hg(2-·-

hydroxybenzyl)thiamine", J.Am.Chem.Soc., 112(20), 7233(1990).

62. A.IAKOVIDIS, N.HADJILIADIS, F.DEHAND, J.P.LAUSSAC and B.LIPPERT, "Complete

displacement of N,O bound amino acids in cis-[NH₃)₂Pt(amac)](NO₃) chelates

by 9-Methylguanine(9-MeG) and 9-Methyladenine (9-MeA). The crystal structure

of cis-[NH₃)₂Pt(9-MeA)₂](NO₃)₂.1.5H₂O", Inorg.Chim.Acta., 175(1), 57 (1990).

63. N.HADJILIADIS and J.MARKOPOULOS, "Infrared Studies on Zwitterionic Thiamine

Derivative Complexes of Platinum(II) and Palladium(II) of the type MLCl₃", Can.

J.Spectry, 35(3), 27 (1990).

64. N.HADJILIADIS and J.MARKOPOULOS, "Infrared Studies on Complexes of Di and

Tetrahydrothiamine and their Phosphate Esters with Platinum(II) and Palladium(II)",

Can.J.Spectry, 35(4), 85 (1990).

65. 8.GAROUFIS, J.HATIRIS and N.HADJILIADIS, "Ternary Complexes of Pt(II) with

Guanosine and Amino Acids of the type trans-[(guo)₂Pt(amacH)₂Cl₂, where

amacH is Glycine, L-Alanine, L-Valine and L-Isoleucine", J.Inorg.Biochem.,

41(3), 195 (1991).

66. N.HADJILIADIS, M.LOULOUDI and I.S.BUTLER, "Infrared and Raman spectra of

2-(·-hydroxybenzyl)thiamine, 2-(·-hydroxycyclohexylmethyl)thiamine their

protonated forms and their complexes with zinc(II), cadmium(II) and mercury(II)",

Spectrochimica Acta, Part A, 47, ΅Τ.13/4, 445 (1991).

67. M.LOULOUDI and N.HADJILIADIS, "Interaction of Co^II, Ni^II and Cu^II with the

Active Aldehyde Derivatives of Thiamine,2-(·-Hydroxybenzyl)thiamine=HBT and

2-(·-Hydroxycyclo-·-methyl)thiamine=HCMT", J. Chem. Soc.Dalton, 1635 (1991).

68. A.IAKOVIDIS, N.HADJILIADIS, J.BRITTEN, I.BUTLER, F.SCWARZ and B.LIPPERT,

"Ternary Complexes of Cis Platin with Amino Acids and Nucleobases. The Crystal

Structure of cis-[(NH₃)₂Pt(1-MeC-N³)(gly-N)](NO₃)",Inorg.Chim.Acta, 184(2), 209 (1991).

69. A.IAKOVIDIS, N.HADJILIADIS and I.S.BUTLER, "Infrared and Raman spectra of

some amino acid (amac) chelates of cis-DDP, of the type cis-[(NH₃)₂Pt(amac)](NO₃),

where amac, the anions of glycine, l-alanine, l-2-aminobutyric acid, l-valine and

l-norvaline, in the region below 1800 cm^-1", Spectrochim.Acta, 47A(11), 1567 (1991).

70. M.LOULOUDI, N.HADJILIADIS and I.S.BUTLER "Solution versus solid state

conformation of II_B group metal complexes of the active aldehyde derivatives

of thiamine", J.Chem.Soc. Dalton Trans., 1401 (1992).

71. V.ALETRAS, N.HADJILIADIS and B.LIPPERT, "Ternary Complexes of trans-

Pt(NH₃)₂Cl₂ with Amino Acids and Nucleobases", Polyhedron, 11, 1359 (1992).

72. V.MAGAFA, G.STAVROPOULOS, T.ZAFIROPOULOS, J.P.LAUSSAC and

N.HADJILIADIS, "Synthesis of the Oligopeptide of Cysteine Boc-Cys(Acm)-

Gly-Ala-Cys(Acm)-OMe and Its Interaction with Hg(II)", C.R.Academie Sciences Paris,

t315, Serie II, 169 (1992).

73. I.S.BUTLER, N.T.KWAI, Y.HUANG, M.LOULOUDI and N.HADJILIADIS, "Effect of

high pressure on the infrared spectra of the thiamine enzyme "active aldehyde"

intermediate 2-(·-hydroxybenzyl)thiamine chloride (HBT) and the

mercury(II) complex Hg(HBT)Cl₃", Inorg. Chim. Acta, 196, 119(1992).

74. A.GAROUFIS, S.KASSELOURI, M.LAMERA-HADJILIADIS and N.HADJILIADIS

"Ternary Complexes of Pt(II) and Other Metals with Nucleosides-Nucleotides and Amino

Acids-Peptides", Chim.Chron. (New Series), 21, 11 (1992).

75. A.GAROUFIS, S.KASSELOURI, A.KATEHANAKIS, G.KALKANIS, S.PERLEPES and

N.HADJILIADIS, "1:1 Metal complexes of 2-(2'-pyridyl)quinoxaline, a ligand

unexpectedly formed by the reaction between 2-acetylpyridine and 1,2-

phenylenediamine", Inorg.Chim.Acta, 207(2), 255 (1993).

76. V.THEODOROU, A.NIKOLAOU and N.HADJILIADIS, "Interaction of[(dien)PtBr]Br

with 6-oxopurine nucleosides", Inorg.Chim.Acta, 208, 91 (1993).

77. I.IAKOVIDIS and N.HADJILIADIS, "Oxidation of the complex cis-

[(NH₃)₂Pt(1-MeC-N³)(N-gly)](NO₃).2H₂O. An unusual rearrangement of the N₃

initial coordination of 1-MeC with Pt(II) to a final amino coordination with

Pt(IV)", Inorg.Chim.Acta, 207(1), 127 (1993).

78. S.KASSELOURI, A.GAROUFIS, G.KALKANIS, S.P.PERLEPES and N.HADJILIADIS,

"Preparation and properties of complexes of divalent transition metal chlorides with

the tetradentate Schiff-base ligand 1,2-bis(2-pyridyl-mehtyleneimino)benzene",

Trans.Met.Chem., 18, 531 (1993).

79. J.C.PLAKATOURAS, S.P.PERLEPES, A.ALBINATI, G.KALKANIS and N.HADJILIADIS,

Preparation and Characterization of [Cu₂Cl₄L₂]; the First Crystal Structure

of a Complex Containing the Novel Ligand 2-(2'-pyridyl)quinoxaline(L) ,

Polyhedron, 12, 2069 (1993).

80. I.IAKOVIDIS and N.HADJILIADIS, "Complex Compounds of Platinum(II) and (IV)

with aminoacids, Peptides and their Derivatives", Coord.Chem.Revs., 135/136

17 (1994).

81. M.LOULOUDI and N.HADJILIADIS, "Structural Aspects of Thiamine Its

Derivatives and their Metal Complexes, in Relation to the Enzymatic Action

of Thiamine Enzymes", Coord.Chem.Revs, 135/136, 429 (1994).

82. P.TSIVERIOTIS, G.VARVOUNIS, Ch.PAPADIMITRIOU and N.HADJILIADIS,

"Ni^II and Co^II Complexes of 2,4-Diaminothieno[2,3-d]pyrimidines", Trans.Met.

Chem., 19, 335 (1994).

83. M.KAMARIOTAKI, A.KARALIOTA, D.STABAKI, TH.BAKAS,V.PAPAEFTHYMIOU,

S.PERLEPES and N.HADJILIADIS, "Coordination complexes of iron(III) with 3-

hydroxy-2-(1H)-pyridinone, 2,3-dihydroxybenzoic acid and 3,4-dihydroxy-

benzoic acid: preparation and characterization in the solid state", Trans. Met.Chem.,

19, 241 (1994).

84. M.LOULOUDI, N.HADJILIADIS, J.P.LAUSSAC and R.BAU "Transition and Group

IIB metal complexes with active aldehyde derivatives of thiamine", Metal Based

Drugs, 1, 221 (1994).

85. N.HADJILIADIS, E.G.BAKALBASIS, J.MROZINSKI, S.P.PERLEPES, F.LINZA and

A.ALBINATI, "Crystal Structure, Magnetic Properties and Quantum-Chemical

Study of the Dihalogen-Bridged [Cu₂X₄L₂]_n Complex, Containing the New

Ligand, L=2-(2'-pyridyl)quinoxaline", Polyhedron, 13, 3209 (1994).

86. V.ALETRAS, N.HADJILIADIS, A.LYMBEROPOULOU-KARALIOTA, I.ROMBECK and

B.LIPPERT, "Ternary complexes of cis- and trans-Pt(NH₃)₂Cl₂ (cis-, trans-DDP)

with 9-methylguanine(9-MeG), the dipeptides glycylglycine (glygly), glycyl-

L-alanine(glyala), glycyl-L-2-aminobutyric acid (gly-2-aba), glycyl-L-norvaline

(glynval), glycyl-L-norleucine(glynleu) and of trans-Pt(NH₃)₂Cl₂ with L-acetylhistidine

(achis)", Inorg.Chim.Acta, 227, 17 (1994).

87. M.LOULOUDI, N.HADJILIADIS and I.BUTLER, Electron Impact Mass Spectroscopy

of Complexes of Co^II Ni^II and Cu^II with Active Aldehyde Derivatives of Thiamin",

Can.J.Appl.Spectry, 29(2), 31 (1994).

88. N.HADJILIADIS, N.FERDERIGOS, G.GASMI, J.L.BUTOUR,H.MAZARGUIL and J.P.

LAUSSAC, "1D and 2D-NMR Study of the Interaction of Platinum Salts with a

Tetrapeptide Containing Cysteinyl Residues Related to the Metal-Binding Site

of Metallothionein", Inorg. Chem., 33, 5057 (1994).

89. S.KASSELOURI, A.GAROUFIS, S.PASCHALIDOU, S.PERLEPES, I.S.BUTLER and

N.HADJILIADIS, "Preparation, structural and physical studies of mercury(II) halide

complexes with the N,N'-chelating biheteroaromatic ligand 2-(2'-pyridyl) quinoxaline(L)",

Inorg.Chim.Acta, 227, 129 (1994).

90. N.HADJILIADIS, K.DODI and M.LOULOUDI (invited main lecture), "Mechanism of

Action of Thiamine enzymes. Role of Metal Ions", "Bioinorganic Chemistry: An Inorganic

Perspective of Life" NATO Advanced Study Institute Rhodos, Greece, 113 (1995).

91. V.ALETRAS, D.HADJILIADIS and N.HADJILIADIS, "On the Mechanism of Action

of cis-DDP", Metal Based Drugs, 2, 53 (1995).

92. P.TSIVERIOTIS, N.HADJILIADIS, F.DAHAN and J.P.LAUSSAC,"Structure of

Methyl 2-formamido-4-diethylaminothieno-[2,3-d]pyrimidine-6-carboxylate",

Acta Cryst. Section C51, 1607 (1995).

93. A.GAROUFIS, M.LOULOUDI, S.KASSELOURI, J.HATIRIS and N.HADJILIADIS,

"Ternary complexes of Cu(II) containing inosine(ino), guanosine (guo) and

the dipeptides, glygly, gly-l-ala,gly-l-val and gly-l-leu", Polyhedron, 14, 1155 (1995).

94. I.S.BUTLER, Y.HUANG and N.HADJILIADIS, "Pressure-tuning infrared spectra

of the thiamine enzyme "active aldehyde" intermediate 2-(·-hydroxy-

cyclohexylmethyl)thiamine chloride(HCMT.HCl) and its complex with

zinc(II), Zn(HCMT)Cl₃", Inorg.Chim.Acta, 231, 191 (1995).

95. S.P.PERLEPES, S.KASSELOURI, A.GAROUFIS, F.LUTZ, R.BAU and N.HADJILIADIS

"Reaction of the biheteroaromatic ligand2-(2'-(pyridyl)quinoxaline(L) with

zinc(II) and cadmium(II)halides: Preparation and characterization of the 1:1

complexes", Polyhedron, 14, 1461 (1995).

96. A.GAROUFIS, S.P.PERLEPES, A.VREUGDENHILL, I.BUTLER and N.HADJILIADIS,

"Synthesis and characterization of 1:2 metal complexes of the bihetero-aromatic

ligand 2-(2'-pyridyl)quinoxaline(L). X-ray structure of [CuL₂](PF₆)",Inorg.Chim.

Acta, 240, 673 (1995).

97. V. ALETRAS, D.HADJILIADIS and N.HADJILIADIS, "Elements of the Mechanism of Action

of the Antitumor drug cis-platin (cis-DDP) and of its second generation derivatives",

"Revision of Clinical Pharmacology and Pharmacokinetics", 13, 153 (1995).

98. A.GAROUFIS, S.PERLEPES, A.SCHREIBER, R.BAU and N.HADJILIADIS,

"Mercury(II) carbon bond cleavage, due to the coordination of the metal by

2-(2'-pyridyl)quinoxaline(L):Preparation and Characterization of [Hg₂I₄L₂]

derived from the Reaction of CH₃HgI and L", Polyhedron, 15, 177 (1996).

99. A.GAROUFIS, S.P.PERLEPES, N.A.FROYSTEIN, J.SLETTEN and N.HADJILIADIS,

"Mercuration of Acetone in the Acetone-Mercury(II)perchlorate 2-(2'-pyridyl)quino-

xaline(L) System", Polyhedron, 15, 1035 (1996).

100. K.DODI, I.P.GEROTHANASSIS, N.HADJILIADIS, A.SCHREIBER, R.BAU, I.BUTLER

and P.J.BARRIE, "Complexes of Zn²⁺, Cd²⁺ and Hg²⁺ with 2-(·-Hydroxybenzyl)

Thiamine Monophosphate Chloride", Inorg.Chem., 35(22), 6513 (1996).

101. P.TSIVERIOTIS and N.HADJILIADIS (main lecture) "Interaction of Platinum(II),

Palladium(II) and Mercury(II) Salts with Histidine and/or Cysteine Containing

Peptides", “Cytotoxic, Mutagenic and Carcinogenic Potential of Heavy Metals Related

to Human Environment", NATO Advanced Study Institute, Przesieka, Poland, 559 (1997).

102. P.TSIVERIOTIS, N.HADJILIADIS and G.STAVROPOULOS, "NMR Study of the Inter-

action of Platinum and Palladium Salts with His-Ala and His-gly-Ala", Inorg.Chim.

Acta, 261, 83 (1997).

103. E.KATSAROU, A.TROGANIS and N.HADJILIADIS, "Binary and Ternary Complexes

of Platinum(II) with the Dipeptide Esters, Gly^.GlyOEt, Gly^.AlaOMe, Gly^.2^.AbaOMe,

Gly^.nValOMe, Gly^.nLeuOMe and the Nucleosides Guo(guanosine) and Cyd(cytidine)",

Inorg.Chim.Acta, 256, 21 (1997).

104. A.PHILIPPOPOULOS, N.HADJILIADIS, C.E.HART, B.DONNADIEU, P.McGOWAN and

R.POILBLANC, "Transition metal derivatives of functionnalized cyclopentadienyl

ligand. 15. Synthesis and structures of aminocyclopentadienyl derivatives of

rhodium(I) and (III) including water soluble compounds", Inorg. Chem.,36, 1842 (1997).

105. S.PERLEPES, A.GAROUFIS, J.SLETTEN, E.G.BAKALBASSIS, J.PLAKATOURAS,

E.KATSAROU and N.HADJILIADIS, "Preparation, Structural Characterization and

Physical Properties of Palladium(II) and Platinum(II) Complexes of the Biheteroaromatic

Ligand 2-(2'-Pyridyl)quinoxaline (L)", Inorg.Chim.Acta, 261, 93 (1997).

106. V.ALETRAS, N.HADJILIADIS, D.STABAKI, A.KARALIOTA, M.KAMARIOTAKI,

I.S.BUTLER, J.PLAKATOURAS and S.P.PERLEPES, "Preparation and Characterization

of the Seven Coordinate Cadmium(II) Complex [Cd(3,4-H₂dhb)₂(H₂O)₃]•HCl•(3,4

- H₃dhb)^.2.5H₂O; The First Structural Determination of a Complex Containing the 3,4-

dihydroxybenzoato(-1)(3,4-H₂dhb)^- Ligand", Polyhedron, 16(8), 1399 (1997).

107. P.TSIVERIOTIS, N.HADJILIADIS and I.SOVAGO, "Proton nuclear magnetic

resonance and potentiometric studies on the palladium(II)-prolylglycylalanylhistidine

binary system", J.Chem.Soc., Dalton, 4267 (1997).

108. E.KATSAROU, C.CHARALAMBOPOULOS and N.HADJILIADIS, "Ternary Complexes

of cis-(NH₃)₂PtCl₂ (cis-DDP) with Guanosine (guo), Cytidine (cyd) and the Amino

Acids Glycine (gly), L-Alanine (ala), L-2-aminobutyric acid (2-aba), L-Norvaline (nval)

and L-Norleucine (nleu)", Metal Based Drugs, 4, 57 (1997).

109. M.LOULOUDI, Y.DELIGIANNAKIS, J.P.TUCHAGUES, B.DONNADIEU and

N.HADJILIADIS,

"Orientation Selective ESEEM Study and Crystal Structure of a Cu^II (thiochrome)Cl₂

Complex", Inorg.Chem., 36, 6335 (1997).

110. V.MAGAFA, G.STAVROPOULOS, P.TSIVERIOTIS and N.HADJILIADIS

"Interaction of HgCl₂ with Tetrapeptides Containing Cysteinyl and Histidinyl

Residues", Inorg.Chim.Acta, 272(1-2), 7 (1998).

111. E.KATSAROU, A.KOLSTAD, N.HADJILIADIS and E.SLETTEN, "¹H NMR Study on

the Interaction between trans-Cl₂Pd(dipeptide)₂, (dipeptide is glycyglycyl and glycyl-l-

norvaline) and the Dodecanucleotide [d(CGCGAATTCGCG)]₂ ", J.Inorg.Biochem.,

70, 265 (1998).

112. A.PHILIPPOPOULOS, R.BAU, R.POILBLANC and N.HADJILIADIS, "Transition metal

derivatives of a ((Dimethylamino)ethyl) cyclopentadienyl ligand. Synthesis and structures

of amino-containing cyclopentadienyl derivatives of Cobalt(I) and (III) including water

soluble compounds", Inorg.Chem., 37, 4822 (1998).

113. S.KASSELOURI, A.GAROUFIS, S.P.PERLEPES, F.LUTZ, R.BAU, S.GOURBATSIS

and N.HADJILIADIS, "Preparation and characterization of the Dinuclear Complexes

[Fe₂Cl₄L₂] and [Fe₂Cl₄L₂]Cl₂", Polyhedron, 17(8), 1281 (1998).

114. A.PHILIPPOPOULOS, R.POILBLANC and N.HADJILIADIS, "Organometallic Rh(I)

and Rh(III) Complexes with [2•(Dimethylamino)ethyl]Cyclopentadienyl", Inorg.Chim.

Acta, 283, 24 (1998).

115. M.LOULOUDI, Y.DELIGIANAKIS and N.HADJILIADIS, "Design and Synthesis

of New Biomimetic Materials by Sol-Gel: A Cu^II(histidine)₂ Complex Covalently

Bonded on a Silica Matrix", Inorg. Chem., 37, 6847 (1998).

116. A.GAROUFIS, S.KASSELOURI, C.MITSOPOULOU, J.SLETTEN, C.PAPADI-

MITRIOU and N.HADJILIADIS, "Metal complexes of the Schift base ligand

L=1,2-bis(2’-pyridylmethyleneimino)benzene with Ni²⁺, Fe²⁺ and Cu²⁺ and their

reactions with bridged bidentate ligands. They crystal structure of the complex

[NiL(H₂O)₂]Cl₂", Polyhedron, 18, 39 (1998).

117. G.MALANDRINOS, M.LOULOUDI, C.A.MITSOPOULOU I.S.BUTLER, R.BAU and

N.HADJILIADIS, "On the Mechanism of Action of Thiamine Enzymes. Crystal Structure

of 2-(·-hydroxyethyl)thiamin pyrophosphate (HETPP). Complexes of HETPP with

Zinc(II) and Cadmium(II)", J.Biol.Inorg.Chem., 3, 437 (1998).

118. Z.YANG, T.BAKAS, A.SANCHEZ-DIAZ, C.CHARALAMBOPOULOS, J,TSANGARIS

and N.HADJILIADIS, "Interaction of Et₂SnCl₂ with 5'-IMP and 5'-GMP",

J.Inorg.Biochem., 72, 133 (1998).

119. S.GOURBATSIS, N.HADJILIADIS, S.P.PERLEPES, A.GAROUFIS and I.S.BUTLER,

"Structural and Spectroscopic Characterization of a Cationic Aquanitratocopper(II)

Complex with the Tetradentate Schiff-base Ligand, N,N'-bis[1-(2-pyridyl)ethyli-

dene]ethane-1,2-diamine", Trans.Met.Chem., 23, 599 (1998).

120. A.GAROUFIS, A.KOUTSODIMOU, N.KATSAROS, C.A.MITSOPOULOU and

N.HADJILIADIS, "Mixed Ligand Ru(II) Complexes with 2,2'-Bipyridine and

2-(2'-Pyridyl)Quinoxaline", Polyhedron, 18, 361 (1998).

121. P.TSIVERIOTIS and N.HADJILIADIS, "Sequence Dependence of the Reactivity

of Histidyl Containing Peptides with Palladium(II) and Platinum(II) Complex Ions.

An NMR Study", J.Chem.Soc., Dalton, 459 (1999).

122 K.DODI, M.LOULOUDI, G.MALANDRINOS and N.HADJILIADIS, "Metal Complexes

with 2-(·-hydroxy-benzyl)thiamin pyrophosphate (HBTPP). Models for Metal Binding

of Thiamin Enzymes", J.Inorg.Biochem., 73, 41 (1999).

123. A.PHILIPPOPOULOS, B.DONNADIEU, R.POILBLANC and N.HADJILIADIS,

"Organometallic Rh(III) Complexes with the Bifunctional Ligand [2-(Dimethylamino)

ethyl]Cyclopentadiene. Crystal Structure of the [{n⁵:n¹-C₅H₄(CH₂)NMe₂}Rh^IIICl₂]

Complex", J.Organomet.Chem., 582(2), 286 (1999).

124. S.GOURBATSIS, S.P.PERLEPES, I.S.BUTLER and N.HADJILIADIS, "Zinc(II)

Complexes Derived from the di-Schiff-base Ligand N,N’-bis[1-pyridin-2-yl)ethylidene]

ethane-1,2-diamine (L_A) and its Hydrolytic-Cleavage Product N-[1-(pyridin-2-yl)ethylidene]

ethane-1,2-diamine (L): Preparation, Characterization and Crystal Structure of the

5-Coordinate Species [ZnLCl₂] ", Polyhedron, 18, 2369 (1999).

125. P.TSIVERIOTIS and N.HADJILIADIS, “Studies on the Interaction of Histidyl Containing

Peptides with Palladium(II) and Platinum(II) Complex Ions”, Coord.Chem.Revs., 190,

171 (1999).

126. S.GOURBATSIS, J.C.PLAKATOURAS, V.NASTOPOULOS, C.J.CARDIN and

N.HADJILIADIS, “Pr{(C₅H₃NC(CH₃): NCH₂)₂}(NO₃)₃]: a monocuclear ten coordinate

lanthanide complex with a tetradentate di-Schiff base”, Inorg.Chem.Commun., 2(10), 468

(1999).

127. M.LOULOUDI, V.NASTOPOULOS, S.GOURBATSIS, S.PERLEPES and N.HADJILIADIS,

“Eight-coordination in nitrato manganese(II) complexes with tetradentate di-Schiff bases

derived from 2-pyridyl ketones: Preparation characterization and catalytic activity for

alkene epoxidation”, Inorg.Chem.Commun., 2(10), 479 (1999).

128. Y.DELIGIANNAKIS, M.LOULOUDI and N.HADJILIADIS, “Electron Spin Envelope

Modulation (ESSEM) Spectroscopy as a Tool to Investigate the Coordination Environment

of Metal Centers”, Coord.Chem.Revs., 204, 1 (2000).

129. G.MALANDRINOS, K.DODI, M.LOULOUDI and N.HADJILIADIS, “On the Mechanism of

Action of Thiamin Enzymes in the Presence of Bivalent Metal Ions”, J.Inorg.Biochem.,

79, 21 (2000).

130. M.LOULOUDI, Y.DELIGIANNAKIS and N.HADJILIADIS, “Design and Synthesis of new

Biomimetic Materials”, J.Inorg.Biochem., 79, 93 (2000).

131. G.MALANDRINOS, M.LOULOUDI, A.KOUKOU, I.SOVAGO, C.DRAINAS and

N.HADJILIADIS, “Zn(II) and cadmium(II) metal Complexes of Thiamin Pyrophosphate

and 2-(α-hydroxyethyl)thiamin pyrophosphate: Models for Activation of Pyruvate

Decarboxylase”, J.Biol.Inorg.Chem., 5, 218 (2000).

132. L.GHYS, M.BIESEMANS, M.GIELEN, A.GAROUFIS, N.HADJILIADIS, R.WILLEM and

J.C.MARTINS, “Μultinuclear 1D and 2D NMR Investigations on the Interaction between

the Pyrimidic Nucleotides 5’-CMP, 5’-dCMP and 5’-UMP and Diethyltin Dichloride in

Aqueous Medium”, Eur.J.Inorg.Chem., 513 (2000).

133. K.VARNAGY, J.SZABO, I SOVAGO, G.MALANDRINOS, N.HADJILIADIS, D.SANNA and

G.MICERA, “Equilibrium and structural studies on the copper(II) complexes of tetra-,

penta- and hexapeptides containing histidyl residues at the C-termini”, J.Chem.Soc.,

Dalton, 467 (2000).

134. P.TSIVERIOTIS, G.MALANDRINOS and N.HADJILIADIS, “Platinum(II) and Palladium(II)

complexes with histidine and histidyl containing peptides. Structure and reactivity”, Revs.

Inorg.Chem., 20(4), 305 (2000).

135. V.ALETRAS, A.KARALIOTA, M.KAMARIOTAKI, D.HATZIPANAYIOTI and

N.HADJILIADIS, “Interaction of Ni(II) with 2,3-dihydrobenzoic acid”, Inorg.Chim.Acta, 312,

151 (2001).

136. A.GAROUFIS, K.KARIDI, N.HADJILIADIS, S.KASSELOURI, J.KOBE, J.BALZARINI and

E.DE CLERCQ, “Synthesis, Characterization and Antiviral Properties of Pd(II) Complexes

with Penciclovir”, Metal Based Drugs, 8, 57 (2001).

137. S.I.MOSTAFA. S.PERLEPES and N.HADJLIADIS, “New Dinuclear Transition Metal

Complexes with the [M₂(μ-dhbq)]ⁿ⁺ Core and 2-(2’-Pyridyl)quinoxaline(L’) as a terminal

ligand: Preparation and Characterization (dhbq^2-=the Dianion of 2,5-Dihydroxy-1,4

- benzoquinone; M=Ag^I, Mn^II, Co^II, Ni^II, Cu^II, Ru^II, Pd^II, Fe^III, Rh^III; n=0,2,4)” Z. Naturforsch.,

56b, 394 (2001).

138. G.MALANDRINOS, M.LOULOUDI, Y.DELIGIANNAKIS and N.HADJILIADIS,

“Two-Dimentional-Hyperfine Sublevel Correlation Spectroscopy Applied in the Study

of a Cu²⁺-[2-(α-Hydroxyethyl)thiamin Pyrophospahte]-[Pentapeptide] System, as a Model

of Thiamin-Dependent Enzymes”, J.Phys.Chem. (B), 105, 7323 (2001).

139. G.MALANDRINOS, M.LOULOUDI, Υ.DELIGIANNAKIS and N.HADJILIADIS,

“Complexation of Cu²⁺ by HETPP and the pentapeptide Asp•Asp•Asn•Lys•Ile: A

Structural Model of the Active Site of Thiamin-Dependent Enzymes in Solution”,

Inorg.Chem., 40, 4588 (2001).

140. A.MYARI, G.MALANDRINOS, Y.DELIGIANNAKIS, J.C. PLAKATOURAS, N.HADJILIADIS,

Z.NAGY and I.SOVAGO, “Interaction of Cu²⁺ with His·Val·His and of Zn²⁺ with

His·Val·Gly·Asp, two peptides surrounding metal ions in Cu, Zn-SOD enzyme”,

J.Inorg.Biochem., 85, 253 (2001).

141. M.MYLONAS, G.MALANDRINOS, J.PLAKATOURAS, N.HADJILIADIS, K.S.KASPRZAK,

A.KREZEL and W.BAL, “Stray Cu(II) may cause oxidative damagewhen coordinated to the -TESHHK-

Sequence derived from the C-terminal tail of histone H2A”, Chem.Res.Toxicol., 14, 1177 (2001).

142. M.LOULOUDI, C.KOLOKYTHA and N.HADJILIADIS,

“Alkene Epoxidation Catalysed by Binuclear Manganese Complexes”,

Journal of Molecular Catalysis A: Chemical., 180, 19 (2002).

143. V.DAGA, S.K.HADJIKAKOU, N.HADJILIADIS, M.KUBICKI, J.SANTOS and I.S.BUTLER,

“Synthesis, spectroscopic and structural characterization of novel di-iodine adducts, with

the heterocyclic thioamides, thiazoline-2-thione (tzdtH), benzothiazole-2-thione (bztzdtH)

and benzimidazole-2-thione (bzimtH)”, Eur.J.Inorg.Chem., 1718, (2002).

144. K.CHARALAMBOPOULOS, S.KARKABOUNAS, E.IOACHIM, V.PAPALIMNEOU,

K.SYRIGOS, A.EVANGELOU, N.AGNANTIS, N.HADJILIADIS,

“Antitumor and Toxic Effects on Wistar Rats of two new Platinum Complexes”, European

Journal of Clin.Investigation, 32(2), 129 (2002).

145. G.GOURNIS, M.LOULOUDI, M.A.KARAKASSIDES, C.KOLOKYTHA, K.MITOPOULOU

and N.HADJILIADIS, “Heterogeneous Clay-Manganese(II) OxidationCatalyst”, Materials

Science and Engineering C: Biomimetic and Supramolecular systems”, 22, 113 (2002).

146. M.MYLONAS, J.C.PLAKATOURAS, N.HADJILIADIS, A.KREZEL and W.BAL,

“Potentiometric and spectroscopic studies of the Interaction of Cu(II) with the

hexapeptides AcThrAlaSerHisHisLysNH₂, AcThrGluAlaHisHisLysNH₂,

AcThrGluSerAlaHisLysNH₂ and AcThrGluSerHisAlaLysNH₂, models of C-terminal tail of

histone H2A”, Inorg.Chim.Acta, 339, 60 (2002).

147. J.H.Z dos SANTOS, I.S.BUTLER, V.DAGA, S.HADJIKAKOY and N.HADJILIADIS,

“High Pressure Fourier transform Micro-Raman Spectroscopic Investigation of Diiodine-

Heterocyclic Thioamide Adducts”, Spectrochim.Acta A, 58, 2725 (2002).

148. CH.VARTZOUMA, M.LOULOUDI, I.S.BUTLER and N.HADJILIADIS, “Practical tethering

of vitamin B₁ on a silica surface via its phosphate group”, Chem.Commun., 522 (2002).

149. M.MYLONAS,A.KREZEL,J.PLAKATOURAS,N.HADJILIADIS and W.BAL,”The binding of

Ni(II) ions to terminally blocked hexapeptides derived from the metal binding of –ESHH-

motif of histone H2A”,J.Chem.Soc.,Dalton, 4296 (2002).

150. M.TSIOURI,J.C.PLAKATOURAS,A.GAROUFIS,V.NASTOPOULOS and N.HADJILIADIS

“Interactions of trivalent lanthanide cations with tetradentate Sciff bases.Part1.Synthesis

and characterization of lanthanide (III) complexes with N,N’-bis(pyridin-2-ylmethylene)

benzene-1,2-diamine”, Inorg.Chem.Commun., 5, 844 (2002).

151. G.MALANDRINOS, M.LOULOUDI and N.HADJILIADIS, “Ternary systems of Zn²⁺ and

Cd²⁺ with 2-(α-hydroxy ethyl)thiamin pyrophosphate (HETPP) and the pentapeptide

Asp·Asp·Asp·Lys·Ile. Implications for the mechanism of thiamin enzymes”,

Inorg.Chim.Acta, 349, 279 (2003).

152. A.GAROUFIS, J.G.LIU, L.N.JI and N.HADJILIADIS,

“Enantioselective binding of Λ- and Δ-[(bpy)₂Ru(HPIP)]Cl₂ (HPIP=2-(2-hydroxyphenyl)

imidazo[4,5-f][1,10]phenanthroline) to hexanucleotide [d(5’-GTCGAC-3’)₂]”,

J.Inorg.Biochem., 93, 221 (2003).

153. P.C.ZACHARIADIS, S.K.HADJIKAKOU, N.HADJILIADIS, A.MICHAILIDES, S.SKOULIKA

Y.MING and Y.XIAOLIN, “Synthesis, study and structural characterization of a new water

soluble hexanuclear silver (I) cluster with the 2-mercaptonicotinic acid with possible antiviral

activity”, Inorg.Chim.Acta, 343, 361 (2003).

154. S.K.HADJIKAKOU, M.N.XANTHOPOULOU, N.HADJILIADIS and M. KUBICKI, “Synthesis

structural characterization and study of mercury(II) iodide complexes with the heterocyclic

thioamides, pyridine-2-thione (pytH) and thiazolidine-2-thione (tzdtH). Crystal structures of

[HgI₂(pytH)₂] and [HgI₂(tzdtH)₂]”, The Can J. Analyt. Science and Spectroscopy, 48, 38

(2003).

155. M.LOULOUDI,K.MITOPOULOU,E.EVANGELOU,Y.DELIGIANNAKIS and

N.HADJILIADIS,”’Homogeneous and Heterogenized Copper(II) Complexes as Catechol

Oxidation Catalysts”,J.Mol.Catalysis A: Chemical, 198, 231 (2003).

156. A.MYARI,M.MALANDRINOS,J.C.PLAKATOURAS,N.HADJILIADIS and I.SOVAGO,

“Interaction of Cu(II) with His.Val.Gly.Asp and of Zn(II) with His.Val.His,two peptides of

the active site of Cu,Zn-superoxide dismutase”, Bioinorganic Chemistry and Applications,

1, 99 (2003).

157. C.D.ANTONIADIS, G.CORBAN, S.K.HADJIKAKOU, N.HADJILIADIS M.KUBICKI,

S.WARNER and I.S.BUTLER, «Synthesis, characterization of (PTU)I₂ (PTU=6-n-propyl-2-thiouracil)

and (CMBZT)I₂ [CMBZT=5-cholro-2-mercaptobenzothiazole) and Possible Implications for the

mechanism of Action of Antithyroid Drugs», Eur.J.Inorg.Chem., 1635 (2003).

158. S.AIME, E.GIANOLIO, A.BARGE, D.KOSTAKIS, J.C.PLAKATOURAS and

N.HADJILIADIS, «Modulation of the Prototropic Exchange Rate at the Water Molecule

Coordinated to Gd(III) Ion», Eur.J.Inorg.Chem., 2045 (2003).

159. N.HADJILIADIS (main lecture), «Recent Research Results in the Laboratory of Inorganic

Chemistry of the University of Ioannina, Greece»,

Topics

1. A.MYARI, A.GAROUFIS and N.HADJILIADIS

«Interactions of Ru(II) bipyridine conjugated peptide complexes with oligonucleotides»

2. M.LOULOUDI, K.DODI, G.MALANDRINOS, N.HADJILIADIS

«Metal coordination compounds as models for the active site of thiamin-dependent enzymes»

3. CH.KOLOKYTHA, CH.VARTZOUMA, K.MITOPOULOU, E.EVANGELOU, M.LOULOUDI,

N.HADJILIADIS

«Developement of biomimetic Materials as heterogenized catalysts»

4. M.MYLONAS, G.MALANDRINOS, J.PLAKATOURAS, N.HADJILIADIS, A.KREZEL and W.BAL

«Interactions of histone model peptides with carcinogenic metal ions (Ni²⁺, Cu²⁺)»

5. S.AIME, E.GIANOLIO, A.BARGE, D.KOSTAKIS, J.C.PLAKATOURAS, N.HADJILIADIS

«Modulation of the prototropic exchange rate at the water molecule coordinated to Gd(III) ion»

6. A.MYARI, N.HADJILIADIS, B.SARKAR

«Peptide fragments as structural analogues of Wilson ATPase

7. A.MYARI, G.MALANDRINOS, J.PLAKATOURAS, N.HADJILIADIS

«Peptide models of the active site of Cu, Zn-SOD»

8. K.KARIDI, A.GAROUFIS, N.HADJILIADIS, J.KOBE, J.BALZARINI, E. De CLEREQ

«Study of Palladium complexes with modified nucleosides as antiviral drugs»

9. S.HADJIKAKOU, N.HADJILIADIS, G.CORBAN, C.D.ANTONIADIS, V.DAGA and M.KUBICKI

«Interaction of anti-thyroid agents with di-iodine and possible implications with the mechanism of

action of anti-thyroid drugs»

10. S.HADJIKAKOU, N.HADJILIADIS, P.ZACHARIADIS and M.XANTHOPOULOU

«Antitumor activity of silver and organotin complex compounds of thioamides»

«Metal-Ligand Interactions in Molecular-, Nano-, and Macro-Systems in Complex

Environments» NATO Advanced Study Institute, Cetraro, Italy, September (2002),

in Metal-Ligand Interactions, Kluwer Academic Publishers, Volume 116, page 497

(2003).

160. M.N.XANTHOPOULOU, S.K.HADJIKAKOU, N.HADJILIADIS, M.SCHÜRMANN,

K.JURKSCHAT, A.MICHAELIDES, S.SKOULIKA, T.BAKAS, J.BINOLIS,

S.KARKABOUNAS and K.CHARALAMBOPOULOS, «Synthesis, structural

characterization and study of organotin(IV) derivatives of heterocyclic thioamides 2-

-mercapto-benzothiazole, 5-chloro-2-mercapto-benzothiazole, 3-methyl-2-mercapto-

benzothiazole and 2-mercapto-nicotinic acid», J.Inorg.Biochem., 96, 425 (2003).

161. M.XANTHOPOULOU, S.HADJIKAKOU, N.HADJILIADIS, M.SCHÜRMANN and

K.JURKSCHAT, J.BINOLIS, S.KARKABOUNAS and K.CHARALABOPOULOS,

«Synthesis of a Novel Triphenyltin(IV) Derivative of 2-mercaptonicotinic Acid with Potent

Cytotoxicity in vitro», Bioinorg. Chem. & Applications, 1, 227 (2003).

162. P.ZACHARIADIS, S.HADJIKAKOU, N.HADJILIADIS, A. MICHAELIDES, S.SKOULIKA,

J.BALZARINI and E. De CLERK, «Synthesis, characterization and in vitro study of the

cytostatic and antiviral activity of new polymeric silver(I) complexes with ribbon structures,

derived from the conjugated heterocyclic thioamide 2-mercapto-3,4,5,6-

tetrahydropyrimidine», Eur. J.Inorg.Chem., 1420 (2004).

163. B.BOKA, I.SOVAGO, A.MYARI and N.HADJILIADIS, «Copper(II) and Zinc(II) Complexes

with the Cu, Zn-SOD Model Peptides Ac•His•Val•His•NH₂ and Ac•His•Val•Gly•Asp•NH₂.

SOD Activity of the Models» J. Inorg. Biochem., 98(1), 113 (2004).

164. A.MYARI, N.HADJILIADIS and A.GAROUFIS, «Synthesis and Characterization of the

Diastereomers of Λ- and Δ-[Ru(bpy)₂(m-bpy-Gly-L-His-L-Lys)]Cl₂. 1H NMR Studies and

Their Interactions with the Deoxynucleotide Duplex d(5’-CGCGAATTCGCC-3’)₂»,

Eur.J.Inorg.Chem., 1427 (2004).

165. C.CHASAPIS, S.HADJIKAKOU, A.GAROUFIS, N.HADJILIADIS, T.BAKAS, M.KUBICKI

and M.YANG, «Organotin(IV) Derivatives of L-cysteine and their in vitro Anti-Tumor Properties»,

Bioinorganic Chemistry and Applications, 2, 43 (2004).

166. M.MYLONAS, A.KREZEL, J.PLAKATOURAS, N.HADJILIADIS and W.BAL,

«Interactions of Zn(II) ions with three His-containing peptide models of histone H2A»,

Bioinorg.Chem. and Applications, 2, 125 (2004).

167 CH.VARTZOUMA, M.LOULOUDI, M.PRODROMIDIS and N.HADJILIADIS,

«Synthesis and Characterization of NAD⁺-modified silica: a convenient immobilization of

biomolecule via its phosphate group», Materials Science and Engineering, C24, 473

(2004).

168. A.GAROUFIS, G.MALANDRINOS and N.HADJILIADIS, «NMR Evidence for a Major

Grove Binding of Both Λ- and Δ-[Ru(bpy)₂(pqx)](PF₆)₂ to the Oligonucleotide

d[CGCGAATTCGCG)₂», Eur.J.Inorg.Chem., 3326 (2004).

169. A.MYARI, N.HADJILIADIS, N.FATEMI and B.SARKAR, «Copper(I) interaction with

model peptides of WD₆ and TM₆ domains of Wilson ATPase: regulatory and mechanistic implications»,

J.Inorg.Biochem., 98, 1483 (2004).

170. C.D.ANTONIADIS, S.K.HADJIKAKOU, N.HADJILIADIS, M.KUBICKI and I.S.BUTLER,

«Synthesis, X-ray Characterization and Studies of the New Ionic Complex [Bis(pyridine-2-yl)disulfide]

Triodide, Obtained by Oxidation of 2-Mercaptopyridine with I₂. Implications in the

Mechanism of Action of Antithyroid Drugs», Eur.J.Inorg.Chem., 4324 (2004).

171. M.MYLONAS, J.PLAKATOURAS and N.HADJILIADIS, «Interactions of Ni(II) and

Cu(II) Ions with Hydrolysis Product of the C-Terminal-ESHH-Motif of Histone H2A Model Peptides.

Association of the Stability of the Complexes Formed with the Cleavage of the –E-S-Bond»,

J.Chem.Soc., Dalton, 4152 (2004).

172. M.LOULOUDI and N.HADJILIADIS, «Hybrid Organic-Inorganic Materials as Biomimetic

Catalysts», Russian Chemistry Journal, 4, 30 (2004).

173. T.KARAVELAS, M.MYLONAS, J.C.PLAKATOURAS, G.MALANDRINOS, N.HADJILIADIS,

P.MLYNARZ and H.KOZLOWSKI, «Coordination properties of Cu(II) and Ni(II) ions towards

the C-terminal peptide fragment -ELAKHA- of histone H2B», J.Inorg.Biochem.,

99, 606 (2005).

174. A.MYARI, N.HADJILIADIS and A.GAROUFIS, «Synthesis and characterization of the

diastereomers Λ- and Δ-[Ru(bpy)₂(m-bpy-L•Arg•Gly-L•Asn-L•Ala-L•His-L•Glu-L•Arg]Cl₂.

¹H_NMR studies on their interactions with the Deoxynucleotide Duplex d[(5’- GCGCTTAAGCGC-3’)₂]

and d[5’-CGCGATCGCG-3)]₂», J.Inorg.Biochem., 99, 616 (2005).

175. M.MYLONAS, K.D.PAPAVASILIOU, J.C.PLAKATOURAS, N.HADJILIADIS and

V.S.MELISSAS, «An Extremely Stable Ni(II) Complex Derived From the Hydrolytic

Cleavage of the C-Terminal Tail of Histone H₂A», J.Inorg.Biochem., 99, 637 (2005).

176. L.BANCI, I.BERTINI, S.CIOFI-BAFFONI, C.T.CHASAPIS, N.HADJILIADIS and

A.ROSATO, «An NMR study of the interaction between the human copper(I) chaperone

and the second and fifth metal-binding domains of the Menkes protein», FEBS Journal

272, 865 (2005).

177. A.GAROUFIS, S.HADJIKAKOU and N.HADJILIADIS, in “METALLOTHERAPEUTIC DRUGS

AND METAL BASED DIAGNOSTICS: THE USE OF METALS IN MEDICINE”, «⁴⁶Pd, The Use of

Palladium-Based Drugs in Medicine», Edited by M.Gielen and E.Tiekink, John Wiley, 2005, page 399.

178. M.MYLONAS, A.KREZEL, J.C.PLAKATOURAS, N.HADJILIADIS and W.BAL,

«Interactions of Transition Metals Ions with His-containing Peptide Models of Histone

H2A», J.Molecular Liquids, 118, 119 (2005).

179. K.KARIDI, A.GAROUFIS, N.HADJILIADIS and J.REEDIJK, «Solid-phase synthesis,

Characterization and DNA binding properties of the first chloro(polypyridyl) ruthenium

conjugated peptide complex»,

J.Chem.Soc., Dalton, 728 (2005).

180. S.K.HADJIKAKOU, C.D.ANTONIADIS, N.HADJILIADIS, M.KUBICKI. J.BINOLIS,

S.KARKABOUNAS and K.CHARALAMBOPOULOS, «Synthesis and characterization of

new water stable antimony(III) complex with pyrimidine-2-thione and in vitro biological

study», Inorg. Chim. Acta, 358, 2861 (2005).

181. K.KARIDI, A.GAROUFIS, A.TSIPIS, N.HADJILIADIS, H.denDULK and J.REEDIJK,

«Synthesis, characterization, in vitro antitumor activity DNA binding properties and

electronic structure (DFT) of the new complex cis-(Cl,Cl)[RuCl₂(terpy)(NO)]Cl»,

J.Chem.Soc. Dalton, 1176 (2005) with the characterization as a hot paper.

182. A.MYARI, N.HADJILIADIS and A.GAROUFIS, «¹H NMR Study of the Enantioselective

Binding of Λ- and Δ-[Ru(bpy)₂(m-bpy-GHK)]Cl₂ to the Deoxynucleotide Duplex d(5’

- G₁G₂C₃C₄A₅A₆T₇T₈C₉G₁₀C₁₁G₁₂-3’)₂», Bioinorg.Chem.& Applications, 3, 109 (2005).

183. C.D.ANTONIADIS, S.K.HADJIKAKOU, N.HADJILIADIS, M.KUBICKI and I.S.BUTLER,

«Synthesis, X-ray characterization and study of new ionic complexes of

2-hydroxypyridine, obtained by oxidation with I₂», New Journal of Chemistry, 29, 714

(2005).

184. G.J.CORBAN, S.K.HADJIKAKOU, N.HADJILIADIS, M.KUBICKI, E.R.T.TIEKINK,

I.S.BUTLER, E.DROUGAS and A.MYLONA-KOSMA, «Synthesis, structural

characterization and study of novel di-iodine adducts with heterocyclic thioamides

N-methyl-benzothiazole-2-thione and benzimidazole-2-thione. Implications with the

mechanism of action of anti-thyroid drugs», Inorg.Chem., 44, 8817 (2005).

185. L.BANCI, I.BERTINI, F.CANTINI, C.T.CHASAPIS, N.HADJILIADIS and A.ROSATO,

“The interaction of a three-domain construct of ATP7A with copper(I)-HAH1: the fourth

N-terminal metal-binding domain is the initial interaction site” “A NMR study of the

interaction of a three-domain construct of ATP7A with copper(I)-HAH1: the interplay of

domains”, J.Biol.Chem., 280, 38259 (2005).

186. G.E.KOSTAKIS, L.CASELLA, N.HADJILIADIS, E.MONZANI, N.KOURKOUMELIS and

J.C.PLAKATOURAS, “Interpenetrated networks from a novel nanometer-sized

pseudopeptidic ligand, bridging water, and transition metal ions with CdSO₄ topology”,

Chem.Commun., 3859 (2005).

187. M.N.XANTHOPOULOU, S.K.HADJIKAKOU, N.HADJILIADIS, S.SKOULIKA,

A.MICHAELIDES, T.BAKAS and N.KOURKOUMELIS, “Structural characterization and

study of {[K(H₂mna)₂]⁺[K(μ-OH)₂]^-∙4H₂O}_n (H₂mna=2-mercaptonicotinic acid). A

supramolecular architecture of inorganic-metal organic hybrid self assembled by

strong hydrogen boding and π-π interactions”, Inorg.Chim.Acta, 359, 215 (2006).

188. C.D.ANTONIADIS, S.K.HADJIKAKOU, N.HADJILIADIS, A.J.BLAKE, C.WILSON,

P.HUBBERSTEY, M.SCHRÖDER, M.BARIL and I.S.BUTLER, “Synthesis, structural

characterization and study of Se analogous of the antithyroid drug 6-n-propyl-2-thiouracil

and their reactivity towards diiodine. Possible implications to the mechanism of action of

anti-thyroid drugs”, Chem.Eur.Journal, 12, 6888 (2006).

189. M.LOULOUDI, G.MALANDRINOS and N.HADJILIADIS, «Thiamine models and

perspectives on the mechanism of action of thiamine-dependent enzymes»,

Royal Society Reviews, 35, 684 (2006).

190. M.TSIOURI, N.HADJILIADIS, T.ASLAN, B.KARINKI and J.C.PLAKATOURAS,

“Interactions of trivalent cations with tetradentate Schiff bases. Synthesis and

characterization of lanthanide(III) complexes with (1S, 2S, N¹E, N²E)-N,N’-bis(pyridine-2-

ylmethylene)cyclohexane-1,2-diamine”, Inorg.Chem.Commun., 9, 429 (2006).

191. M.N.XANTHOPOULOU, S.K.HADJIKAKOU, N.HADJILIADIS, M.KUBICKI,

S.KARKABOUNAS, K.CHARALABOPOULOS, N.KOURKOUMELIS and T.BAKAS,

“Synthesis and characterization of a new chloro-di-phenyltin(IV) complex with thioamide

2-mercapto-nicotinic acid. Study of its influence upon the catalytic oxidation of linoleic

acid to hydroxyperoxylinoleic acid by the enzyme Lipoxygenase”, J.Organomet.Chem.,

691, 1780 (2006).

192. L.BANCI, I.BERTINI, F.CANTINI, I.C.FELLI, L.GONELLI, N.HADJILIADIS, R.PIERATELLI,

A.ROSATO and P.VOULGARIS, “Atx1-Cu2: metal-mediated protein-protein interaction”,

Nature Chemical Biology, 2(7), 367 (2006).

193 ARSLAN, C.ÖGŘETIR, M.TSIOURI, J.C.PLAKATOURAS and NICK HADJILIADIS,

“Interactions of trivalent lanthanide cations with a hexadentate Schiff base derived from

the condensation of ethylenediamine with 8-hydroxyquinoline-2-carboxaldehyde”,

J.Coord.Chem., 60(6),699(2007).

194. K.KARIDI, A.GAROUFIS, N.HADJILIADIS, M.LUTZ, A.SPEK and J.REEDIJK,

“Photoinduced DNA cleavage by ruthenium polypyridine nitro complexes. Synthesis,

characterization and DNA binding studies”, Inorg.Chem., 45(25),10282(2006).

195. I.S.BUTLER, J.F.MENG, C.ANTONIADIS, S.K.HADJIKAKOU and N.HADJILIADIS,

“Pressure-tuning Raman Spectra of Selected Di-iodine Thioamide Adducts: Model

Compounds for Anti-thyroid Drug Activity”, Bioinorganic Chemistry & Applications,

ID 68542,Pages 1-5(2006).

196. G.KOSTAKIS, F.NORDLANDER, N.HADJILIADIS, M.HAUKKA and J.PLAKATOURAS,

“Two 3D supramolecular architectures from zinc-hydrogen aconitate, one-D polymers”,

Inorg.Chem.Commun., 9, 915 (2006).

197. C.ANTONIADIS, A.J.BLAKE, S.K.HADJIKAKOU, N.HADJILIADIS, P.HUBBERSTEY,

M.SCHRÖDER and C.WILSON, “Structural Characterization of selenium and selenium-

Diiodine analogues of the antithyroid drug 6-n-propyl-2-thiouracil and its alkyl derivatives”,

Acta Cryst. B62, 580 (2006).

198. N.LEKKAS, E.R.T.TIEKINK, N.HADJILIADIS and A.GAROUFIS, “Synthesis and

characterization of Pd(II) and Pt(II) complexes with triazolopyrimidine derivatives. The

crystal structure of the [Pd₂L₂Cl₄] where L = 5,7-dimethyl-1,2,4-triazolo[1,5-α]pyrimidine”,

Inorg.Chim.Acta, 359, 4297 (2006).

199. C.KALLAY, K.VARNAGY, G.MALANDRINOS, N.HADJILIADIS, D.SANNA and

I.SOVAGO, “Copper(II) complex of terminally protected pentapeptides containing three

histidyl residues in alternating positions, Ac∙His∙Xaa∙His∙Xaa∙His∙NH₂”,

Dalton Transaction, 4545 (2006).

200. S.HADJIKAKOU and N.HADJILIADIS, “Interaction of thioamides, selenoamides and

amides with di-iodine”, Bioinorg.Chem. & Applications, ID 60291,Pages 1-10(2006).

201. C.VARTZOUMA, E.EVAGELLOU, Y.SANAKIS, N.HADJILIADIS and M.LOULOUDI,

“Alkene epoxidation by homogeneous and heterogenized manganese(II) catalysts

With hydrogen peroxide”, J.Mol.Catalysis, 263, 77 (2006).

202. A.MYARI, A.GAROUFIS, N.HADJILIADIS and V.BRABEC, “NMR and Photocleavage

Study of A- and Δ-[Ru(bpy)₂(m-GHK)]Cl₂ with the Oligonucleotide Duplex

d[CGCGATCGCG]₂”, J.Biol.Inorg.Chem.12, 279(2007):12,293(2007).

203. D.ZOIS, CH.VARTZOUMA, Y.DELIGIANNAKIS, N.HADJILIADIS, L.CASELLA,

E.MONZANI and M.LOULOUDI, “Active catalytic centers in silica-supported Cu(II) and

Mn(II) biomimetic complexes: correlation between catalytic and EPR data”,

J.Mol.Catal A:Chemical,261,306(2007)

.204. A.STAMATIS, G.MALANDRINOS, I.S.BUTLER, N.HADJILIADIS and M.LOULOUDI,

“Intermediates of thiamine catalysis immobilized on silica surfaces as active biocatalysts

For α-ketoacid decarboxylaiton”, J.Mol.Catalysis A:Chemical,267,120(2007).

205. M.N.XANTHOPOULOU, S.K.HADJIKAKOU, N.HADJILIADIS, M.KUBICKI, S.SKOULIKA,

T.BAKAS, M.BARIL and I.S.BUTLER, “Synthesis, Structural Characterization and

Biological Studies of Six and Five Coordinated Organotin(IV) Complexes with the

Thioamides 2-mercapto-benzothiazole, 5-chloro-2-mercapto-benzothiazole and 2-

mercapto-benzoxazole”, Inorg.Chem., 46(4),1187(2007).

206. S.ZARTILAS, N.KOURKOUMELIS, S.HADJIKAKOU, N.HADJILIADIS, P.ZACHARIADIS,

M.KUBICKI, A.Yu.DENISOV and I.S.BUTLER, “A new silver(I) aggregate having an

Octagonal Ag4S4 core where μ3-S bonding interactions lead to a nanotube assembly

That exhibits quasiaromaticity”, Eur.J.Inorg.Chem.,1219(2007)

207.A.STAMATIS.G.MALANDRINOS,M.LOULOUDI and N.HADJILIADIS,”New Perspectives on

Thiamine Catalysis.From Enzymic to Biomimetic Catalysis”,Bioinorg.Chem.and

Applications,ID 23286,(2007),7 pages.

208. M.N.XANTHOPOULOU, S.K.HADJIKAKOU, N.HADJILIADIS, E.R.MILAEVA,

J.A.GRACHEVA, V. Yu. TYURIN, K.C.CHRISTOFORIDIS, N.KOURKOUMELIS,

A.K.METSIOS, K.CHARALAMBOPOULOS and S.KARKABOUNAS, “Biological

Studies of New Organotin(IV) Complexes of Thioamide Ligands. Implication with the

Mechanism of Action of Tin Antitumor Drugs”, Eur.J.Med.Chem., 43,327(2008).

209. E.R.MILAEVA, O.A.GERASIMOVA, A.L.MAXIMOV, E.A.IVANOVA, E.A.KARACHANOV,

M.LOULOUDI and N.HADJILIADIS, “The Catalytic Activity of Immobilized on Silica

Metalloporphyrins Bearing Antioxidative 2,6-Di-tert-ButylphenyllPendants”, Catalysis

Communications,8,2069(2007).

210. S.ZARTILAS, S.K.HADJIKAKOU, N.HADJILIADIS,L.KYROS,N.KOURKOUMELIS

M.KUBICKI,M.BARIL,I.S.BUTLER,S.KARKABOUNAS and J.BALZARINI,

“Tetrameric 1:1 and monomeric 1:3 complexes of silver (I) halides with tri(p-tolyl)-phosphine;

a structural and biological study.”Inorg.Chim.Acta., Inorg.Chim.Acta.,362,1003(2009).

211.M.N.XANTHOPOULOU,S.K.HADJIKAKOU,N.HADJILIADIS,N.KOURKOUMELIS,E.R.MILA

EVA,J.A.GRACHEVA,Y.Y.TYURIN,I.VERGINADES,S.KARKABOUNAS,M.BARIL and I.S.

BUTLER,”Biological Studies of Organotin(IV)Complexes with 2-mercapto-pyrimidine”Russ.

Chem.Bulletin,56(4),767(2007).

212.K.KARIDI,J.REEDIJK,N.HADJILIADIS and A.GAROUFIS,”Synthesis,Characterization and

DNAbindingPropertiesofOligopyridine-Ruthenium(II)-AminoAcid conjugates”,

J.Inorg.Biochem.,101,1483(2007)

213.T.KARAVELLAS,G.MALANDRINOS,N.HADJILIADIS,M.MLYNARZ , H.KOZLOWSKI,

M.BARSAM and I.BUTLER, “Coordination Properties of Cu(II) and Ni(II) Ions,towards

the C-terminal Peptide Fragment -TYTEHA of Histone H4”,Dalton Trans.,1215(2008),with

the characterization as a hot paper.

214.I.I.OZTURK,S.K.HADJIKAKOU,N.HADJILIADIS,N.KOURKOUMELIS,M.KUBICKI,M.BARIL

and I.S.BUTLER,”Synthesis,Structural Characterization and Antitumor Activity of New

Antimony(III) Complexes with Thioamides.The influence of the solvent on the geometry

of the complexes”,Inorg.Chem.46,8652(2007)

216.M.N.XANTHOPOULOU,S.K.HADJIKAKOU,N.HADJILIADIS,N.KOURKOUMELIS,E.R.

MILAEVA,YU.A.GRACHEVA,V.YU.TYURIN,I.VERGINADIS,S.K.KARKABOUNAS,M.

BARIL and I.S.BUTLER,”Biological Studies of Organotin(IV)Complexes with 2-mercapto-

Pyrimidine”Russian Chemical Bulletin,International Edition,56,767(2007)

217.C.KALLAY,Z.NAGY,K.VARNAGY,G.MALANDRINOS,N.HADJILIADIS and I.SOVAGO

“Thermodynamic and structural characterization of the copper(II)complexes of peptides

containingboth histidyl and aspartyl residues”Bioinorg.Chem.Applications,ID 30394,

doi:10.1155/2007/30394,2007,9 pages

218.S.K.HADJIKAKOU and N.HADJILIADIS,”Antiproliferativeand antitumor activity of organotin . compounds.

Coordination Chemistry Revs.(DOI:10.1016/j.ccr.2007.12.026.),253,235(2009)

219.S.K.HADJIKAKOU,I.I.OZTURK,M.N.XANTHOPOULOU,P.C.ZACHARIADIS.S.ZARTILAS

and N.HADJILIADIS,”Synthesis,structural characterization and antitumor properties of

new organotin(IV),silver(I) and antimony(III) complexes with thioamides”Invited by the

the Editor to J.Inorg.Biochem. 102,1007(2008).

220.V.BALAS,S.K.HADJIKAKOU,N.HADJILIADIS,N.KOURKOUMELIS,M.E.LIGHT,M.HUR-

STHOUSE,A.K.METSIOS and S.KARKABOUNAS.

“Crystal Structure and Antitumor Activity of the Novel Zwitterionic Complex tris-n-

Butyltin(IV) with 2-Thiobarbituric acid”.Bioinorg. Chem. & Applications.

Doi:10.1155/2008/654137,2008,5 pages.

221. C.KALLAY,K.VARNAGY,G.MALANDRINOS,N.HADJILIADIS,D.SANNA and I.SOVA-

GO, ,”Thermodynamic and Structural Characterization of the Macrochelates Formed in

The Reactions of Copper(II) and Zinc(II) Ions with Peptides of Histidine”

Inorg.Chim.Acta., 362,935(2009)

222.K.PANAGIOTOU,M.PANAGOPOULOU,T.KARAVELAS,V.DOKOROU,A.HAGARMAN,

J.SOFFER,R.SCHWEIZER-STENNER,G.MALANDRINOS and N.HADJILIADIS

“Cu(II) and Ni(II) Interactions with the Terminally Blocked Hexapeptide Ac-Leu.Ala.His.Tyr.

Asn.Lys.amide,(LAHYNK) Model of Histone H2B(80-85).,Bioinorganic Chemistry and

Applications,doi:10.1155/2008/257038,2008,10 pages.

223.M.N.XANTHOPOULOU,N.KOURKOUMELIS,S.K.HADJIKAKOU,N.HADJILIADIS,M.

KUBICKI,S.KARKABOUNAS and T.BAKAS,”Structural and biological studies of organotin

(IV) derivatives with 2-mercapto-benzoic acid and 2-mercapto-4-methyl-pyrimidine”

Polyhedron.,27,3318(2008).

224.S.I.MOSTAFA and N.HADJILIADIS,”Biologically active 2-thione-4,6-diamino-5-hydroxy-

Pyrimidine transition metal complexes”,Trans.Metal Complexes,33,529(2008).

225.I.E.PARIGORIDI,G.J.CORBAN,S.HADJIKAKOU,N.HADJILIADIS,N.KOURKOUMELIS,

G.KOSTAKIS,V.PSYHARIS,C.P.RAPTOPOULOU and M.KUBICKI, « Structural motifs

of diiodine complexes with amides and thioamides »,Dalton Transactions,5159(2008)

226.S.RAJKOVIC,C.KALLAY,R.SERENYI,G.MALANDRINOS,N.HADJILIADIS,D.SANNA

and I.SOVAGO,”Complex formation processes of terminally protected peptides

containing two or three histidyl residues.Characterization of the mixed metal complexes of

peptides”,Dalton Transactions,5059(2008) as a hot paper.

227.S.I.MOSTAFA,C.PAPATRIANTAFYLLOPOULOU,S.PERLEPES and N.HADJILIADIS

“The First Metal Complexes of 4,6-diamino-1-hydro-5-hydroxy-pyrimidine-2-thione:

Preparation,Physical and Spectroscopic Studies and Antimicrobial Properties”

Bioinorg.Chem.and Applications, ID 646873,12 pages(2008).

228.A.GAROUFIS,S.K.HADJIKAKOU and N.HADJILIADIS,”Palladium coordination

compounds as antiviral,antifungal,antimicrobial and antitumor agents Coordination . Chemistry Reviews,253,1384(2009).

229. K.ZAVITSANOS,A.M.P.C.NUNES,G.MALANDRINOS,C.KALLAY,I.SOVAGO,V.MAGAFA

And N.HADJILIADIS,”Interaction of Ni(II) and Cu(II) with the 63-93 fragment of histone

H2B”,Dalton Transactions ,6179(2008) as a hot paper

230. S.K.HADJIKAKOU and N.HADJILIADIS,”Interaction of Thioamides,Selenoamides

andAmideswith Di-iodine.A study of the Mechanism of Action of AntithyroidDrugs”.Procee-

dings of the 9^th Eurasia Conference on Chemical Sciences,Antalya,Turkey,September

6-9,2006.,Book,Innovations in Chemical Biology,Chapter 13,DOI:10.1007/978-1-4020-

6955-0,Springer Science+Business Media B.V.2009

231.A.MYARI and N.HADJILIADIS,”DNA recognition and binding by peptide-metal complex

Conjugates”,Chapter in “Metal Complex-DNA Interactions”,Blackwell publishers,Chapter12

(2009).

232.I.I.OZTURK,S.K.HADJIKAKOU^],N.HADJILIADIS,N.KOURKOUMELIS,M.KUBI-

CKI, A. J. TASIOPOULOS, H.SHLEIMAN,P.BOCANEGRA and I.S.BUTLER

"Novel antimony(III)bromide complexes with thioamides.Synthesis,characterization and

antitumor properties",Inorg.Chem., 48, 2233, 2009.

233.A.M.P.C.NUNES,K.ZAVITSANOS,R.del CONTE,G.MALANDRINOS

and N.HADJILIADIS,"Interaction of Histone H2B(63-93) with Ni(II).An NMR Study"

Dalton Transactions, 1904(2009),as a hot paper

234.M.A.ABDELLAH,S.K.HADJIKAKOU,N.HADJILIADIS,M.KUBICKI,T.BAKAS,

N.KOURKOUMELIS,Y.V.SIMOS,S.KARKABOUNAS,M.BARSAN and I.BUTLER

"Synthesis,characterization and biological studies of organotin(IV)derivatives with o- or

p-hydroxybenzoic acids"Bioinorganic Chemistry and Application, (2009),Article ID

542979.12 pages.

235.K.N.KOUROULIS,S.K.HADJIKAKOU,N.KOURKOUMELIS,M.KUBICKI,L.MALE,

M. HURSTHOUSE, S. SKOULIKA, A. K. METSIOS, V.Y. TYURIN, A.V. DOLGANOV,

E.R. MILAEVA and N. HADJILIADIS

"Synthesis, structural characterization and in vitro cytotoxicity of new Au(III) and Au(I)

complexes with thioamides.Oxidation and desulfuration of thioamides by Au(III) ions “

Dalton, 10446(2009).

236.I.OZTURK,S.FILIMONOVA,S.K.HADJIKAKOU,N.KOURKOUMELIS,V.DOKOROU,E.MANOS,

A.J.TASIOPOULOS,M.M.BARSAN,I.S.BUTLER,E.R.MILAEVA,J.BALZARINI and N.HADJILIADIS

“Structural motifs and biological studies of new antimony(III) iodide complexes with thiones”

Inorg.Chem.,49,488(2010)

237.A.M.P.C.NUNES,K.ZAVITSANOS,G.MALANDRINOS and N.HADJILIADIS,”Coordination of Cu2+ and

Ni2+ with the Histone Model Peptide of H2B N-terminal tail (1-31 residues).A spectroscopic

study".Inorg.Chem. 39,4369 (2010).

238.A.M.NUNES,K.ZAVITSANOS,R.DEL CONTE,G.MALANDRINOS

and N.HADJILIADIS,"The possible role of 94-125 peptide fragment of Histone H2B

in nickel induced carcinogenesis."Inorg.Chem.,49,5658(2010)..

239.K.ZAVITSANOS,A.M.NUNES,G.MALANDRINOS and N.HADJILIADIS,

“Copper effective binding with 32-62 and 94-125 peptide fragments of histone H2B",

J.Inorg.Biochem.,105,102(2011)

240.I.I.OZTURK,S.K.HADJIKAKOU,A.C.TSIPIS,G.MALANDRINOS,N.KOURKOUMELIS,

M.J.MANOS,A.J.TASIOPOULOS,M.E.LIGHT,M.HURSTHOUSE,P.E.BOCANEGRA,

I.S.BUTLER and N.HADJILIADIS,

"Structural characterization of the{3(HBPMTU).3X.nH2O}salts (BMTU=1,3-bis(3-pyridyl

methyl )-2-thiourea and x=Cl,Br,I).A polychlorine network based on O…Cl and OH…Cl

interactions".J.Coord.Chem.,64,201(2011).

241.G.J.GORBAN,S.HADJIKAKOU, A.TSIPIS, M.KUBICKI ,T.BAKAS,N.HADJILIADIS

"Inhibition of peroxidase catalyzed iodination by thioamides experimental and theoretical

of the antithyroid activity of thioamides",New Journal of Chemistry,35,213(2011).

242.G.MALANDRINOS, .K.ZAVITSANOS,A.M.NUNES and N.HADJILIADIS,

"Peptide models in the study of the mechanism of carcinogenesis by heavy metals"

Pure and Applied Chemistry,83,1751(2011).

243 .K.ZAVITSANOS,A.M.NUNES, G.MALANDRINOS and N.HADJILIADIS,

"DNA strand breakage induced by Cu(II) and Ni(II),in the presence of peptide models of

Histone H2B",J.Inorg.Biochem.,105,1329(2011)

244.I.I.OZTURK,N.KOURKOUMELIS,S.K.HADIKAKOU,M.J..MANOS,A.TASIOPOULOS,

I.S.BUTLER,J.BALZARINI and N.HADJILIADIS

"Interaction of Antimony(III) chloride with thiourea,2-mercapto-5-methyl-benzimidazole,3-

-5-mercaptobenzothiazole,2-mercaptopyrimidine and 2- mercaptopyridine",J.Coord.Chem.,

64,3859(2011)

245.I.I.OZTURK,A.K.METSIOS,S.FILIMONOVAORLOVA,N.KOURKOUMELIS,

S.K.HADJIKAKOU,M.J.MANOS,A.J.TASIOPOULOS,S.KARKABOUNAS,E.R.MILAEVA

and N.HADJILIADIS,"Study on Single Crystal Structure of Antimony(III) Bromide

Complex with 3-methyl-2.mercaptobenzothiazole and biological activity of

some antimony(III) bromide complexes with thioamides", Med.Chem.Research,21(11),3523

(2012),DOI 10.1007/s00044-011-9905-9(2011).

246.G.J.CORBAN,C.D.ANTONIADIS,S.K.HADJIKAKOU,N.KOURKOUMELIS,V.Yu TY-

URIN,A.DOLGANO,E.R.MILAEVA,M.KUBICKI,P.V.BERNHARDT,E.R.T.TIEKINK,S.

SKOULIKA and N.HADJILIADIS

"Reactivity of di-iodine towards thiol.De-sulfuration reaction of 5-nitro-2-mercapto-

Benzimidazole upon reaction with di-iodine",Heteroatom Chemistry,23,498(2012) .

247.N.HADJILIADIS,"Metal Ions in Biological Systems.Bioinorganic Chemistry"(In Greek)

Aristotle(edition of Cypriot Pharmacists Graduates of the Aristotle University Thessaloniki)

28,page10(2012).

248.D.B.SHPAKOVSKY,C.N.BANTI,G,BEAULIEUHOULE,N.KOURKOUMELIS,M.MA-

NOLI,M.J.MANOS,A.J.TASIOPOULOS,S.K.HADJIKAKOU,E.R.MILAEVA,K.CHARA-

LABOPOULOS,T.BAKAS,I.S.BUTLER and N.HADJILIADIS,

"Synthesis,Structural Characterization and in vitro Inhibitory Studies Against Human Breast

Cancer of the bis-(2,6-tert-butylphenol)tin(IV)Dichloride and its Complexes with Hetero-

Cycle Thioamides",Dalton Trans., 2012, 41,14568-14582, DOI: 10.1039/c2dt31527k..

249.V.I.BALAS,C.N.BANTI,N.KOURKOUMELIS,S.K.HADJIKAKOU,G.D.GEROMICHALOS,

D.SAHPAZIDOU,L.MALE,M.B.HURSTHOUSE,B.BEDNARZ,M.KUBICKI,K.CHARALABOPOULOS and N.HADJILIADIS,”Reactivity and in vitrobiological studies of organotin(IV)precursors;Selective

Inhibitory activity against humanbreast cancer cells,positive to estrogen receptors”

Australian Journal of Chemistry, 2012, 65, 1625-1637,DOI: http://dx.doi.org/10.1071/CH12448.
(Research Front)

250.N.HADJILIADIS and C.WENTRUP,:12^TH Eurasia Conference on Chemical Sciences:,Aust.J.Chem.,

65,1561(2012)

251.N.HADJILIADIS,”The antitumor drug cis-Platin(cis-DDP).” (In Greek)(edition of Cypri-

ot Pharmacists Graduates of the Aristotle University Thessaloniki)

252.N.HADJILIADIS,”The antitumor drug cis-Platin(cis-DDP).” (In Greek)Aristotle(edition of Cypri-

ot Pharmacists Graduates of the Aristotle University Thessaloniki)

253.G.MALANDRINOS and N.HADJILIADIS,"Cu(II)-histones interaction related to toxicity-

carcinogenesis",Coord.Chem.Revs.262,55-71(2014)

254.C.N.BANTI,D.C.CHARALAMPOU,N.KOURKOUMELIS,A.M.OWCZARZAK,

M.KUBICKI,S.K.HADJIKAKOU,N.HADJILIADIS,"Mono-nuclear cis-Pd chloride com-

plex of the thio-nucleotide analogue 5-methyl-thiouracyl and its biological activity"

POLYHEDRON,87,251(2014).

255.S.K.HADJIKAKOU,I.OZTURK,C.BANTI,N.KOURKOUMELIS and N.HADJILIADIS,

"Recent advances on antimony(III/V)compounds with potential activity against tumor cells"

J.Inorg.Biochem.,accepted for publication.