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Patents

Chapters in International Books after reviewing

Publications in Research Peer Review Journals

1991-1995

1996-2000

2001-2005

2006-2010

2011-2015

2016-2020

 

 

 

Patents

[1] Metallodrug of ciprofloxacin-silver with antimicrobial properties.

Univ of Ioannina, S.K. Hadjikakou, C.N Banti, I.P. Milionis, I.Sainis, N Kourkoumelis, V Psyxharis, C Raptopoulou, Greek patent No 1008941

 

 

Chapters in International Books after reviewing

[1] 46Pd The Use of Palladium-based Drugs in Medicine

A. Garoufis, S.K. Hadjikakou and N. Hadjiliadis,in Metallotherapeutic Drugs and Metal-Based Diagnostic Agents: The Use of Metals in Medicine, Wiley-Europe publishers 2005, Editing by Marcel Gielen and Edward Tiekink, Chapter 21, p. 399-420.

 

[2] Interaction of Thioamides, Selenoamides and Amides with Di-iodine: A Study of the Mechanism of Action of Anti-thyroid Drugs

Sotiris K. Hadjikakou and Nick Hadjiliadis in Innovations in Chemical Biology, Springer 2008, Chapter 13 p. 141-149

 

 

Publications in Research Peer Review Journals

1991-1995

[1] Synthesis and photochemical study of Cu(I) complexes with tri-p-tolylphosphine and heterocyclic thiones. The crystal structure of [CuCl(pymtH)(p-CH3C6H4)3P]2.

P. Karagiannidis, S. K. Hadjikakou, P. Aslanidis and A. untas, Inorg.Chim.Acta, 178, 27-34, (1990).

 

[2] Synthesis and photolysis of mixed Cu(I) complexes with thiones and tri-p-tolylphosphines or triphenylphosphine; Crystal structure of bis [copper(I) (1,3-thiazolidine-2-thione) (tri-p-tolylphosphine) chloride].

S. K. Hadjikakou, P. Aslanidis, P. Karagiannidis, D. Mentzafos and A. Terzis, Polyhedron, 10, 935, (1991).

 

[3] Synthesis and photolysis of a new series of Cu(I) complexes with tri-m-tolylphosphine and heterocyclic thiones. The crystal structure of bis [-iodo (pyridine-2-thione) (tri-m-tolylphosphine) copper(I)].

S. K. Hadjikakou, P. Aslanidis, P. Karagiannidis, A. Hountas and A. Terzis, Inorg.Chim.Acta, 184, 161-166, (1991).

 

[4] Synthesis and photolysis of a new series of Cu(I) complexes with tri-o-tolylphosphine and heterocyclic thiones. The crystal structure of [thiazolidine-2-thione) (tri-o-tolylphosphine) copper(I) bromide].

S. K. Hadjikakou, P. Aslanidis, P. Karagiannidis, D. Mentzafos and A. Terzis, Inorg.Chim. Acta, 186, 199-204, (1991).

 

[5] Copper(I) complexes with tri-o-tolylphosphine and heterocyclic thione ligands. Crystal strucures of [(pyrimidine-2-thione) (tri-o-tolylphosphine) copper(I) chloride] and [(pyriidine-2-thione) (tri-o-tolylphosphine) copper(I) iodide].

S. K. Hadjikakou, P. Aslanidis, P. Karagiannidis, A. Aubry and S. Skoulika, Inorg.Chim. Acta, 193, 129, (1992).

 

[6] Study of mixed ligand Copper(I) complexes with tri-m-tolylphosphine (tmtp) and heterocyclic thiones. Crystal structures of bis[-S (benzimidazoline-2-thione)(tmtp) copper(I) chloride] and bis[-Br (thiazolidine-2-thione)(tmtp) copper(I)]

S. K. Hadjikakou, P. Aslanidis, P. D. Akrivos, P. Karagiannidis, B. Kojic-Prodic and M. Luic, Inorg.Chim. Acta, 197, 31, (1992).

 

[7] Electrochemical reduction of CuI mixed ligands complexes with phosphines and heterocyclic thiones in accetonitrile solutions with glassy carbon electrode.

P. Karagiannidis, S. K. Hadjikakou and N. Papadopoulos, Polyhedron, 11, 2947, (1992).

 

[8] Study of the geometric preferences of copper(I) halid coordnation compounds with triarylphosphines. Crystal structures of [Cu2I2{P(m-tolyl)3}3].

P.D. Akrivos, S. K. Hadjikakou, P. Karagiannidis, D. Mentzafos and A. Terzis, Inorg.Chim. Acta, 206, 163, (1993).

 

[9] Study of the geometric preferences of copper(I) halid coordnation compounds with triarylphosphines. Crystal structures of [CuBr{P(o-tolyl)3}]2 and [CuCl{P(o-tolyl)3}]2.

S. K. Hadjikakou, P.D. Akrivos, P. Karagiannidis, D. Mentzafos and A. Terzis, Inorg.Chim. Acta, 210, 27-31, (1993).

 

[10] Four coordinate copper(I) iodide complexes with triphenylphosphine and heterocyclic thione ligands. The crystal structure of [bis(triphenyl phosphine (pyrimidine-2-thione)copprer(I) iodide].

P. Aslanidis, S. K. Hadjikakou, P. Karagiannidis M. Gdaniec and S. Kosturkiewicz, Polyhedron, 12, 2221, (1993).

 

[11] On the molecular structure of gold(I) complexes with heterocyclic thiones. The structure of Au bis(1,3-thiazolidine-2-thione)2 chloride hydrate.

P.D. Akrivos, S.K. Hadjikakou, P. Karagiannidis, M. Gdaniec and S. Kosturkiewicz, Polyhedron, 13, 753, (1994).

 

[12] Mixed Ligand Coordination Compounds of Copper(I) with Heterocyclic Thiones and Tertiary Phosphines. The Crystal Structure of bis(quinoline-2-thione) bistriphenyl phosphino Copper(I) Ethylsulfate Hemihydrate.

P. D. Akrivos, S. K. Hadjikakou, P. Karagiannidis, M. Luic and B. Kojic-Prodic, J Coord. Chem., 31, 273, 1994.

 

[13] Preparation and spectral studies of dinuclearmixed-ligand copper(I) complexes. The crystal structure of bis[-S(Pyridine-2-Thione)(tmtp) Copper(I)Bromide].

P. Aslanidis, S. K. Hadjikakou, P. Karagiannidis, B. Kojic-Prodic and M. Luic, Polyhedron., 13, 3119, 1994.

 

[14] Electrochemical reduction of dinuclears Cu(I) mixed ligands complexes with tri-m-tolylphosphine and heterocyclic thiones.

S.K. Hadjikakou, P. D. Akrivos, P. Karagiannidis and N. Papadopoulos, Polyhedron,14, 2999,1995.

 

1996-2000

[15] Synthesis and characterisation of copper(I) complexes with triphenylphosphine and heterocyclic thione ligands: the crystal structure of (thiazoline-2-thione)(bis- triphenylphosphine) copper(I) chloride

P. Aslanidis, S.K. Hadjikakou, P. Karagiannidis and P.J. Cox, Inorg. Chim. Acta, 271, 243, 1998.

 

[16] Metal ions-Drugs Interactions. Preparation and Properties of Manganese(II) Cobalt(II) and Nickel(II) Complexes of Diclofenac with Potentially Anti-inflammatory Activity. Behaviour in the Oxidation of 3,5-di-butylcathechol..

D.Kovala-Demertzi, S. K. Hadjikakou, M. A. Demertzis. J. Deligiannis, J. Inorg. Biochem, 69, 223, 1998.

 

[17] Anti-inflammatory properties of Diclofenac Transition Metalloelement Complexes.

D. M. Konstandinidou, A. Kourounakis, M. Yiangou, L. Hadjipetrou, D. Kovala-Demertzi, S.K. Hadjikakou, M.A. Demertzis, J. Inorg. Biochem, 70, 63, 1998.

 

[18] Synthesis and Structural Characterization of the First Organotin Complex of Piroxicam. An extended Network system via Non-Hydrogen, Hydrogen Bonding Linkages and C-H-- Contacts.

S.K. Hadjikakou, M.A. Demertzis, J. R. Miller and D. Kovala-Demertzi, J. Chem Soc. Dalton, 663, 1999.

 

[19] Palladium(II) and Platinium(II) Complexes of Pyridine-2-Carbaldehydde Thiosemicarbazone with Potential Biological Activity. Synthesis, Structure and Spectral Properties. Extented Network Via Hydrogen Bond Linkages of [Pd(Pytsc)Cl].

Dimitra Kovala-Demertzi, John R. Miller, Nikolaos Kourkoumelis, Sotiris K. Hadjikakou, Mavroudis A. Demertzis, Polyhedron, 18, 1005-1013, 1999.

 

[20] Synthesis, spectroscopic and computational studies plus crystal structure of [(bis-benzo-1,3-thiazolidine-2-thione)(bis-triphenylphoshine)copper(I)] [chloro(benzothiazolidine-2-thione)(bis-triphenylphoshine)copper(I)].

P. J. Cox, P. Aslanidis, P. Karagiannidis and S. K. Hadjikakou, Polyhedron, 18, 1999, 1501-1506

 

[21] Synthesis, characterisation and study of mercury(II) chloride complexes with triphenylphosphine and heterocyclic thiones. The crystal structures of [(benzothiazole-2-thionato)-(benzothiazole-2-thione) (bis-triphenylphosphine) chloro mercury(II)]and [(2-dichloro){(bis-pyrimidine-2-thionato)-mercury(II)}{(bis-triphenylphosphine) mercury(II)}] at 100 K

S.K. Hadjikakou*, M. Kubicki, Polyhedron 19, (2000) 2231-2236.

 

[22] Organotin adducts with pyrimidinethione: crystal structure of dimethyldi(pyrimidine-2-thiolato)tin(IV) and diphenyldi(pyrimidine-2-thiolato)tin(IV)

Sotiris K. Hadjikakou, Mavroudis A. Demertzis, Maciej Kubicki, Dimitra Kovala-Demertzi, Appl. Organometal. Chem. 14, 727734, (2000).

 

[23] Organotin-Drug interaction. Organotin Adducts of Tenoxicam. Synthesis and Characterisation of the first organotin complex of Tenoxicam.

Mavroudis A. Demertzis, Sotiris K. Hadjikakou, Dimitra Kovala-Demertzi, Aglaia Koutsodimou, Maciej Kubicki, Helv. Chim. Acta, 83, (2000), 2787

 

[24] Silver(I) complexes with heterocyclic thiones and tertiary phosphines as ligands. Part 4. Dinuclear complexes of silver(I) bromide: the crystal structure of bis[bromo-(pyrimidine-2-thione)(triphenylphosphine)silver(I)]

Phil J. Cox, Paraskevas Aslanidis, Petros Karagiannidis, Sotiris Hadjikakou, Inorg. Chim. Acta, 310 (2000) 268272.

 

 

2001-2005

 

[25] Synthesis, characterisation and study of mercury(II) bromide complexes with triphenylphosphine and heterocyclic thiones. The crystal structures of the [bis(tri-phenylphosphine) di-bromo mercury(II)] and [di-bromo (pyrimidine-2-thionato) (triphenylphosphine) mercury(II)]. An extended intra-molecular linkages via N-HBr and C-HBr interactions.

M. Kubicki, S. K. Hadjikakou* and M.N. Xanthopoulou, Polyhedron, 20, (2001), pp 2179-2185.

 

[26] Synthesis, spectroscopic and structural characterization and study of novel di-iodine adducts with the heterocyclic thioamides thiazoline-2-thione (tzdtH), benzothiazole-2-thione (bztzdtH) and benzimidazole-2-thione (bzimtH).

Vasiliki Daga, Sotiris K. Hadjikakou, Nick Hadjiliadis, Maciej Kubicki, Joze H.Z. Santos and Ian S. Butler, Eur. J. Inorg Chem., 2002, (7), 1718-1728.

 

[27] High Pressure Micro FT-RAMAN Spectroscopic Investigation of Diiodine Heterocyclic Thioamide Adducts

Joze H.Z. Santos and Ian S. Butler, Vasiliki Daga, Sotiris K. Hadjikakou, Nick Hadjiliadis, Spectrochimica Acta Part A, 58 (2002) 27252735

 

[28] Copper(I) Halide Complexes With Triphenylphosphine And Heterocyclic Thione Ligands: The Crystal Structures Of Bis-[-S (Benzimidazole-2-Thione)(Triphenylphosphine)Copper(I)Chloride], [Bis-(Triphenylphosphine) (Benzimidazole-2-Thione) Copper(I)Iodide] And [Bis-(Triphenylphosphine) (Benzothiazole-2-Thione) Copper(I)Iodide

P. Aslanidis, P.J. Cox, P. Karagiannidis, S.K. Hadjikakou, and C.D. Antoniadis, Eur. J. Inorg Chem., 2002, 2216-2222.

 

[29] Solvent-controlled assembling by hydrogen bridges and halogen-halogen interactions of novel organotin oxo clusters.

Michael Mehring, Giuseppina Gabriele, Sotiris Hadjikakou, Markus Schrmann, Dainis Dakternieks, Klaus Jurkschat, Chem. Comm., 2002, 834-835.

 

[30] Synthesis, study and structural characterisation of a new water soluble hexanuclear silver(I) cluster with the 2-mercapto-nicotinic acid with possible antiviral activity.

Panagiotis C. Zachariadis, Sotiris K. Hadjikakou*, Nick Hadjiliadis*, Adonis Michaelides, Stavroula Skoulika,, Yang Ming, and Yu Xiaolin, Inorg. Chim. Acta, 2003, 343, 361-365.

 

[31] Synthesis structural characterisation and study of mercury(II) iodide complexes with the heterocyclic thioamides, pyridine-2-thione (pytH) and thiazolidine-2-thione (tzdtH). Crystal structures of [HgI2(pytH)2] and [HgI2(tzdtH)2]

Sotiris K. Hadjikakou*, Marianna N. Xanthopoulou, Nick Hadjiliadis*, Maciej Kubicki, Canadian Journal of Analytical Sciences and Spectroscopy, 2003, 48, 38-45.

 

[32] Synthesis and characterisation of (PTU)I2 (PTU=6-n-propyl-thiouracil) and (CMBZT)I2 (CMBZT= 5-chloro-2-mercapto-benzothiazole) and possible implications with the mechanism of action of anti-thyroid drugs

Constantinos D. Antoniadis, Ghada Corban, Sotiris K. Hadjikakou*, Nick Hadjiliadis*, Maciej Kubicki, Stephanie Warner and Ian S. Butler, Eur. J. Inorg Chem., 2003, 1635-1640.

 

[33] Synthesis of a novel triphenyltin(IV) derivative of 2-mercaptonicotinic acid with strong cytotoxicity in vitro.

Marianna N. Xanthopoulou, Sotiris K. Hadjikakou*, Nick Hadjiliadis*, Markus Schürmann, Klaus Jurkschat, Jayne Binolis, Spyros Karkabounas, Konstantinos Charalabopoulos, Bioinorganic Chemistry & Applications., 2003, 1(3-4), 227-231.

 

[34] Synthesis, structural characterisation and biological activity of organotin(IV) derivatives of heterocyclic thioamides 2-mercapto-benzothiazole, 5-chloro-2-mercapto-banzothiazole, 3-methyl-2-mercapto- benzothiazole and 2-mercapto-nicotinic acid.

Marianna N. Xanthopoulou, Sotiris K. Hadjikakou*, Nick Hadjiliadis*, Markus Schürmann, Klaus Jurkschat Adonis Michaelides, Stavroula Skoulika, Thomas Bakas, Jane J Binolis, Spyros Karkabounas and Constantinos Haralampopoulos, J. Inorg. Biochem., 2003, 96 (2-3), 425-434.

 

[35] Interaction of organotin(IV) derivatives with the mercapto amino acid L-cysteine. The de-sulphuration of L-cysteine.

Christos T. Chasapis, Sotiris K. Hadjikakou*, Achilles Garoufis, Nick Hadjiliadis*, Thomas Bakas, Maciej Kubicki, and Yang Ming, Bioinorganic Chemistry and Applications, 2003, 2(1-2), 43-54.

 

[36] Synthesis, characterization and in vitro study of the cytostatic and antiviral activity of new polymeric silver(I) complexes with ribbon structures, derived from the conjugated heterocyclic thioamide 2-mercapto-3,4,5,6-tetrahydro-pyrimidine.

Panagiotis C. Zachariadis, Sotiris K. Hadjikakou*, Nick Hadjiliadis*, Adonis Michaelides, Stavroula Skoulika, Jan Balzarini and Erik De Clercq. Eur. J. Inorg Chem., 2004, 1420-1426.

 

[37] Synthesis, X-ray characterization and study of a new ionic complex of 2-mercapto-pyridine, obtained by oxidation with I2. Implications in the mechanism of action of anti-thyroid drugs..

Constantinos D. Antoniadis, Sotiris K. Hadjikakou*, Nick Hadjiliadis*, Maciej Kubicki, Ian S. Butler, Eur. J. Inorg Chem., 2004, 4324-4329

 

[38] Effects of non steroid anti-inflammatory drugs in membrane bilayers

I. Kyrikou, S.. Hadjikakou, D. Kovala, T. Mavromoustakos, Chemistry and Physics of Lipids, 132 (2004) 157169.

 

[39] Diphenylbis(Hpiroxicam)tin(IV), [Ph2Sn(Hpir)2]

Dimitra Kovala-Demertzi, Aglaia Koutsodimou, Angeliki Galani, Sotiris K. Hadjikakou, Mavroudis A. Demertzis, Marianna Xanthopoulou, John R. Miller and Christopher S. Frampton, Appl. Organometal. Chem. 2004; 18: 501502.

 

[40] Exploring the Structural and Bonding Variability in the Mixed-Ligand Bromo(Triarylphosphine)(Benzimidazole-2- Thione)Dicopper(I) Complexes with Diamond-Shaped Cu2( - )2 Core Structures

Sotiris K. Hadjikakou*, Constantinos D. Antoniadis, Paraskevas Aslanidis, Philip J. Cox and Athanassios C. Tsipis*, Eur. J. Inorg Chem., 2005, 1442-1452.

 

[41] Synthesis, X-ray characterization and study of new ionic complexes of 2-pyridone, obtained by oxidation with I2.

Constantinos D. Antoniadis, Sotiris K. Hadjikakou*, Nick Hadjiliadis*, Maciej Kubicki, and Ian S. Butler, New J. Chem., 2005, 29, 714720.

 

[42] Synthesis and characterization of new water stable antimony(III) complex with pyrimidine-2-thione and in vitro biological study

Sotiris K. Hadjikakou*, Constantinos D. Antoniadis, Nick Hadjiliadis*, Maciej Kubicki, Jayne Binolis, Spyros Karkabounas, Konstantinos Charalabopoulos., Inorg. Chim., Acta, 2005, 358, 2861-2866.

 

[43] Synthesis, structural characterization and computational studies of novel di-iodine adducts with the heterocyclic thioamides N-methyl-benzothiazole-2-thione and benzimidazole-2-thione. Implications with the mechanism of action of anti-thyroid drugs.

Ghada J. Corban, Sotiris K. Hadjikakou*, Nick Hadjiliadis*, Maciej Kubicki, Edward R.T. Tiekink, Ian S. Butler, Evangelos Drougas, Agnie M. Kosmas, Inorg. Chem., 2005, 44, 8617-8627

 

 

2006-2010

 

[40] Exploring the Structural and Bonding Variability in the Mixed-Ligand Bromo(Triarylphosphine)(Benzimidazole-2- Thione)Dicopper(I) Complexes with Diamond-Shaped Cu2( - )2 Core Structures

Sotiris K. Hadjikakou*, Constantinos D. Antoniadis, Paraskevas Aslanidis, Philip J. Cox and Athanassios C. Tsipis*, Eur. J. Inorg Chem., 2005, 1442-1452.

 

[41] Synthesis, X-ray characterization and study of new ionic complexes of 2-pyridone, obtained by oxidation with I2.

Constantinos D. Antoniadis, Sotiris K. Hadjikakou*, Nick Hadjiliadis*, Maciej Kubicki, and Ian S. Butler, New J. Chem., 2005, 29, 714720.

 

[42] Synthesis and characterization of new water stable antimony(III) complex with pyrimidine-2-thione and in vitro biological study

Sotiris K. Hadjikakou*, Constantinos D. Antoniadis, Nick Hadjiliadis*, Maciej Kubicki, Jayne Binolis, Spyros Karkabounas, Konstantinos Charalabopoulos., Inorg. Chim., Acta, 2005, 358, 2861-2866.

 

[43] Synthesis, structural characterization and computational studies of novel di-iodine adducts with the heterocyclic thioamides N-methyl-benzothiazole-2-thione and benzimidazole-2-thione. Implications with the mechanism of action of anti-thyroid drugs.

Ghada J. Corban, Sotiris K. Hadjikakou*, Nick Hadjiliadis*, Maciej Kubicki, Edward R.T. Tiekink, Ian S. Butler, Evangelos Drougas, Agnie M. Kosmas, Inorg. Chem., 2005, 44, 8617-8627.

 

[44] Synthesis, structural characterization and study of {[K(H2mna)2]+ [K(-OH)2]- 4H2O}n (H2mna= 2-mercapto-nicotinic acid). A supramolecular architecture of inorganic / metal-organic hybrid self-assembled by strong hydrogen bonds and - iinteractions.

Marianna N. Xanthopoulou, Sotiris K. Hadjikakou*, Nick Hadjiliadis*, Adonis Michaelides, Stavroula Skoulika*, Nikolaos Kourkoumelis, Thomas Bakas, Inorg. Chim., Acta, 2006, 359 (2006) 215220

 

[45] Novel organotin(IV) compounds derived from bis(organostannyl)methanes. Synthesis and crystal structures of bis[diphenyl(pyridin-2-onato)stannyl]methane}] and bis[(bromophenyl(pyrimidine-2-thionato)stannyl]methane∙C7H8

Sotiris K. Hadjikakou*, Klaus Jurkschat, Markus Schürmann, J. Organomet. Chem. 2006, 691, 16371642 .

 

[46] Synthesis and characterization of a new chloro-di-phenyltin(IV) complex with thioamide 2-mercapto-nicotinic acid. Study of its influence upon the catalytic oxidation of linoleic acid to hydroperoxylinoleic acid by the enzyme Lipoxygenase.

Marianna N. Xanthopoulou, Sotiris K. Hadjikakou*, Nick Hadjiliadis*, Maciej Kubicki, Spyros Karkabounas, Konstantinos Charalabopoulos, Nikolaos Kourkoumelis and Thomas Bakas. J. Organomet. Chem. 2006, 691, 17801789.

 

[47] Synthesis, structural characterization and study of Se analogues of the antithyroid drug 6-n-propyl-2-thiouracil and its alkyl derivatives. Easy formation of dimeric Se-Se compounds of the iodine adducts in polar solvent and/or de-selenetion.

Constantinos D. Antoniadis[a], Sotiris K. Hadjikakou*[a], Nick Hadjiliadis*[a], Athanasios Papakyriakou[a], Martin Baril[b] and Ian S. Butler[b].Chem. Eur. J., 2006, 12, 6888 6897

 

[48] Structural characterisation of selenium and selenium-diiodine analogues of the antithyroid drug 6-n-propyl-2-thiouracil and its alkyl derivatives

Constantinos D. Antoniadis, Alexander J. Blake, Sotiris K. Hadjikakou, Nick Hadjiliadis, Peter Hubberstey, Martin Schröder and Claire Wilson, Acta Cryst, B. 2006, B62, 580591.

 

[49] Pressure-tuning Raman Spectra of Di-iodine Thioamide Adducts: Model Compounds for Anti-thyroid Drug Activity

Ghada J. Corban, Constantinos Antoniodis, Sotiris K. Hadjikakou, Nick Hadjiliadis, Jin-Fang Meng and Ian S. Butler, Bioingranic Chemistry and Applications, Volume 2006, Article ID 68542, Pages 15.

 

[50] Interaction of Thioamides, Selenoamides and Amides with Di-Iodine.

Sotiris K. Hadjikakou and Nick Hadjiliadis, Bioinorganic Chemistry and Applications, Volume 2006, Article ID 60291, Pages 110.

 

[51] Synthesis, Structural Characterization and Biological Studies of Six and Five Coordinated-Organotin(IV) Complexes with the Thioamides 2-mercapto-benzothiazole, 5-chloro-2-mercapto-benzothiazole and 2-mercapto-benzoxazole.

Marianna N. Xanthopoulou, Sotiris K. Hadjikakou*, Nick Hadjiliadis*, Maciej Kubicki, Stavroula Skoulika, Thomas Bakas, Martin Baril and Ian S. Butler, Inorg. Chem., 2007, 46, 1187-1195.

 

[52] A new silver(I) aggregate having an octagonal Ag4S4 core where 3-S bonding interactions lead to a nano-tube assembly which exhibits quasi-aromaticity.

Sotiris Zartilas, Nikolaos Kourkoumelis, Sotiris K. Hadjikakou*, Nick Hadjiliadis*, Panagiotis Zachariadis, Maciej Kubicki, Alexey Yu. Denisov and Ian S. Butler, Eur J. Inorg. Chem., 2007, 12191224..

 

[53] Biological studies of organotin(IV) complexes with 2-mercapto-pyrimidine.

M.N. Xanthopoulou, S.K. Hadjikakou*, N. Hadjiliadis* , N. Kourkoumelis, E.R. Milaeva, J.A. Gracheva, V-Y. Tyurin, I. Verginades, S. Karkabounas, M. Baril and I.S. Butler, Russian Chemical Bulletin, 2007, 56, 767-773.

 

[54] Synthesis, structural characterization and biological studies of new antimony(III) complexes with thioamides. The influence of the solvent on the geometry of the complexes.

I.I. Ozturk, S.K. Hadjikakou*, N. Hadjiliadis*, N. Kourkoumelis, M. Kubicki, M. Baril, I.S. Butler, Jan Balzarini, Inorg. Chem., 2007, 46, 8652-8661.

 

[55] Biological Studies of New Organotin(IV) Complexes of Thioamide Ligands.

M.N. Xanthopoulou, S.K. Hadjikakou*, N. Hadjiliadis*, E.R. Milaeva, J.A. Gracheva, V-Y. Tyurin, N. Kourkoumelis, K.C. Christoforidis, A.K. Metsios, S. Karkabounas and K.Charalabopoulos, Eur. J Med Chem., 2008, 43(2) pp 327-335

 

[56]. Synthesis, Structural Characterization and Biological Study of New Organotin(IV), Silver(I) and Antimony(III) Complexes with Thioamides.

S.K. Hadjikakou, I.I. Ozturk, M.N. Xanthopoulou, P.C. Zachariadis, S. Zartilas, N. Hadjiliadis J Inorg Biochem., 2008, 102, 10071015.

 

[57] Crystal structure and antitumor activity of the novel zwitterionic complex of tri-n-butyltin(IV) with 2-thiobarbituric acid.

V.I. Balas, S.K. Hadjikakou, N. Hadjiliadis, N. Kourkoumelis, M.E. Light, M. Hursthouse, A.K. Metsios, S. Karkabounas, Bioinorganic Chemistry and Applications, 2008, , Article ID 654137, 5 pages.

 

[58] Structural and biological studies of organotin(IV) derivatives with 2-mercato-benzoic acid and 2-mercapto-4-methyl-pyrimidine.

M.N. Xanthopoulou, N. Kourkoumelis, S.K. Hadjikakou, N. Hadjiliadis, M. Kubicki, S. Karkabounas and Thomas Bakas. Polyhedron, 2008, 27 (2008) 33183324.

 

[59] Structural motifs of diiodine complexes with amides and thioamides.

I-E. Parigoridi, G.J. Corban, S.K. Hadjikakou*, N. Hadjiliadis*, N. Kourkoumelis, G. Kostakis, V. Psycharis, C.P. Raptopoulou, M. Kubicki, Royal Chemical Society Dalton Trans., 2008, 5159 -5165.

 

[60] Tetrameric 1:1 and monomeric 1:3 complexes of silver(I) halides with tri(p-tolyl)-phosphine: A structural and biological study

S. Zartilas, S.K. Hadjikakou, N. Hadjiliadis, N. Kourkoumelis, L. Kyros, M. Kubicki, M. Baril, I.S. Butler, S. Karkabounas and J. Balzarini, Inorg. Chim. Acta., 2009, 362, 10031010.

 

[61] Anti-proliferative activity of organotin compounds

S.K. Hadjikakou, N. Hadjiliadis, Coord. Chem. Rev. 2009, 253, 235249.

 

[62] Palladium coordination compounds as anti-viral, anti-fugal, antimicrobial and anti-tumor agents.

A. Garoufis, S.K. Hadjikakou and N. Hadjiliadis, Coord. Chem. Rev., 2009, 253, 13841397

 

[63] New Antimony(III) Bromide Complexes with Thioamides: Synthesis, Characterization, and Cytostatic Properties

I.I. Ozturk, S.K. Hadjikakou*, Nick Hadjiliadis*, N. Kourkoumelis, M. Kubicki, A.J. Tasiopoulos, H. Scleiman, M.M. Barsan, I.S. Butler, J. Balzarini, Inorg. Chem., 2009, 48, 2233-2245.

 

[64] Synthesis, characterization and biological studies of organotin(IV) derivatives with o- or p-hydroxy-benzoic acids

M.A. Abdellah, S.K. Hadjikakou*, N. Hadjiliadis*, M. Kubicki, T. Bakas. N. Kourkoumelis, Y.V. Simos, S. Karkabounas, M. Barsan and I.S. Butler, Bioinorganic Chemistry and Applications, 2009, Article ID 542979, 12 pages

 

[65] Synthesis, structural characterization and in vitro cytotoxicity of new Au(III) and Au(I) complexes with thioamides. Oxidation and desulfuration of thioamides by Au(III) ions.

K.N. Kouroulis, S.K. Hadjikakou*, N. Hadjiliadis*, N. Kourkoumelis, M. Kubicki, L. Male, M. Hursthouse, S. Skoulika, A. K. Metsios, V.Y. Tyurin, A.V. Dolganov, E.R. Milaeva, Dalton Trans., 2009, 1044610456.

 

[66] Structural motifs and biological studies of new antimony(III) iodide complexes with thiones.

I. Ozturk, S. Filimonova, S.K. Hadjikakou*, N. Kourkoumelis, V. Dokorou, E. Manos, A.J. Tasiopoulos, M.M. Barsan, I.S. Butler, E.R. Milaeva and Jan Balzarini, N. Hadjiliadis*, Inorg Chem., 2010, 49, 488501.

 

[67] Structural, photolysis and biological studies of the bis(2-chloro)-tris(triphenylphosphine)-di-copper(I) and chloro-tris(triphenylphosphine)-copper(I) complexes. Study of copper(I)-copper(I) interactions. Possible photo activated metallotherapeutic agent.

Konstantinos A. Lazarou, Barbara Bednarz, Maciej Kubicki, Ioannis I. Verginadis, Konstantinos Charalabopoulos, Nikolaos Kourkoumelis* and Sotiris K. Hadjikakou*, Inorg Chim Acta , 2010, 363, 763772.

 

[68] Structural properties, cytotoxicity and anti-inflammatory activity of silver(I) complexes with tris(p-tolyl)phosphine and 5-chloro-2-mercapto-benzothiazole.

Loukas Kyros, Nikolaos Kourkoumelis, Maciej Kubicki, Louise Male, Mike Hursthouse, Ioannis I. Verginadis, Efthalia Gouma, Spyros Karkabounas, Konstantinos Charalabopoulos and Sotiris K. Hadjikakou*, Bioinorganic Chemistry and Applications, 2010, Article ID 386860, 12 pages doi:10.1155/2010/386860.

 

 

2011-2015

 

[69] Inhibition of Peroxidase-Catalyzed Iodination by Thioamides. Experimental and Theoretical Study of the induced Antithyroid Activity of thioamides

Ghada J. Corban, Sotiris K. Hadjikakou, Athanasios C. Tsipis, Maciej Kubicki, T. Bakas, Nick Hadjiliadis, New Journal of Chemistry, 2011, 35, 213 - 224. Hot Article

 

[70] Inhibition of lipoxygenase (LOX) and anticancer activity caused by gold(I) mixed ligands complexes of triphenylphosphine and thioamides.

E. Georgiou, A. Metsios, N. Kourkoumelis, S. Karkabounas, K. Charalabopoulos, A. Badeka, S.K. Hadjikakou*, Journal of Enzyme Inhibition and Medicinal Chemistry, 2011, Vol. 26, No. 4, Pages 592-597: (doi: 10.3109/14756366.2010.529807)

 

[71] Formation and characterization of the ionic salts {3[BPMTU]+3[X]-nH2O} (BPMTU = 1,3-Bis(3-pyridylmethyl)-2-thiourea and X = Cl, Br, I). A novel supramolecular architecture based on OCl- bonding interactions and strong charge-assisted OHCl- and NHCl- hydrogen bonding network.

I.I. Ozturk, S.K. Hadjikakou*, A.C. Tsipis, G. Malandrinos, N. Kourkoumelis, M.J. Manos, A.J. Tasiopoulos, M.E Light, M. Hursthouse, P.E. Bocanegra, I.S. Butler, N. Hadjiliadis*, J. Coord. Chem., 2011, 64, 202221

 

[72] Anticancer and cytotoxic effects of a novel triorganotin compound in malignant cell lines and tumor bearing Wistar rats

I. Verginadis, S. Karkabounas, I. Simos, E. Kontargiris, M. Drosos, S. Hadjikakou, A. Batistatou, K. Charalabopoulos, A. Evangelou, European Journal of Pharmaceutical Sciences, 2011, 42, 253-261

 

[73] Synthesis, structural characterization and biological studies of the triphenyltin(IV) complex with 2-thiobarbituric acid.

V.. Balas, I.I. Verginadis, G.D Geromichalos, N. Kourkoumelis, L. Male, M.B. Hursthouse, K.H Repana, E. Yiannaki, K. Charalabopoulos, T. Bakas, S.K. Hadjikakou*, European Journal of Medicinal Chemistry, 2011, 46, 2835-2844

 

[74] Synthesis, structural characterization and biological studies of novel mixed ligand Ag(I) complexes with tri-phenylphosphine and aspirin or salicylic acid.

M. Poyraz, C.N. Banti, N. Kourkoumelis, V. Dokorou, M.J. Manos, M. Simčič, S. Golič-Grdadolnik, T. Mavromoustakos, A.D. Giannoulis, I.I. Verginadis, K. Charalabopoulos and S.K. Hadjikakou*, Inorg Chim. Acta 2011, 375, 114121

 

[75] Bromo-tris(triphenylphosphine)silver acetonitrile solvate hydrate

Anita M. Owczarzak, Loukas Kyros, Sotiris K. Hadjikakou and Maciej Kubicki, Acta Cryst. 2011. E67, m1507.

 

[76] Interaction of antimony(III) chloride with the thioamides: thiourea, 2-mercapto-5-methyl-benzimidazole, 3-methyl-2-mercaptobenzothiazole, 2-mercaptopyrimidine and 2-mercaptopyridine.

I.I. Ozturk, N. Kourkoumelis, S. K. Hadjikakou, M. J. Manos, A. J. Tasiopoulos, S. Butler, J. Balzarini and N. Hadjiliadis., J. Coord. Chem., 2011, 64, , 38593871

 

[77] Copper(I)/(II) or silver(I) salts towards 2-mercaptopyrimidine; An exploration of a chemical variability with possible biological implications.

G.K. Batsala, V. Dokorou, N. Kourkoumelis, M.J. Manos, A.J. Tasiopoulos, T. Mavromoustakos, M. Simčič, S. Golič-Grdadolnik and S.K. Hadjikakou, Inorg. Chim. Acta., 382 (2012) 146157

 

[78] Synthesis, characterization and biological studies of new antimony(III) halide complexes with -thiocaprolactam

I.I. Ozturk, C.N. Banti, M.J. Manos, A.J. Tasiopoulos, N. Kourkoumelis, K. Charalabopoulos, S.K. Hadjikakou, J Inorg Biochem., 109, (2012) 5765.

 

[79] Structural characterization of the antimony(III) bromide complex with 3-methyl-2-mercaptobenzothialoe. Study of the biological activity of antimony(III) bromide complexes with thioamides.

I.I. Ozturk, A.K. Metsios, S. Filimonova, N. Kourkoumelis, S.K. Hadjikakou, E. Manos, A.J. Tasiopoulos, S. Karkabounas, E.R. Milaeva, N. Hadjiliadis, Med Chem Res, 2012 21:35233531.

 

[80] Structural characterization of polymeric potassium salts with 2-thiobarbituric acid. Influence of organotin(IV) chlorides on potassium cation salvation.

Maciej Kubicki, Anita Owczarzak, Vasilios . Balas, SotirisK. Hadjikakou, J. Coord Chem. , Vol. 65, 2012, 11071117

 

[81] Stabilization of poly-iodides: structural influences of the cationic disulfides of 2-mercapto-3,4,5,6-tetrahydro-pyrimidine and 2-mercatpo-pyrimidine.

Anita Owczarzak, Maciej Kubicki, Nikolaos Kourkoumelis, Sotiris K. Hadjikakou, RCS Advances, 2012, 2, 28562867

 

[82] Mixed ligands silver(I) complexes with anti-inflammatory agents which can bind to lipoxygenase and calf thymus-DNA, modulating their function, inducing apoptosis.

C.N. Banti, A.D. Giannoulis, N. Kourkoumelis, A. Owczarzak, M. Poyraz, M. Kubicki, K. Charalabopoulos and S.K. Hadjikakou, Metallomics 2012, 4, 545-560. (Metallomics Issue 6 Front Page. article among top ten accessed articles from the online version of Metallomics)

 

[83] Reactivity of di-iodine towards thioamides. De-sulfuration reaction of 5-nitro-2-mercapto-benzimidazole upon of its reaction with di-iodine.

G.J. Corban, C.D. Antoniadis, S.K. Hadjikakou, N. Kourkoumelis, M. Kubicki, P.V. Bernhardt, E.R.T. Tiekink, S. Skoulika, N. Hadjiliadis, Heteroatom Chemistry, 2012, 23(5), 498-511.

 

[84] Synthesis, structural characterization and cytotoxicity of the antimony(III) chloride complex with N,N-Dicyclohexyldithiooxamide

I.I. Ozturk, O.S. Urgu, C.N. Banti, N. Kourkoumelis, A.M. Owczarzak, M. Kubicki, K. Charalabopoulos and S.K. Hadjikakou, Polyhedron, 2012, accepted for publication

 

[85] Photo-activated metallotherapeutics; Copper(I) or silver(I) mixed ligand complexes with 2-mercaptopyrimidine and triphenylphosphine.

A. Velalopoulou, G.K. Batsala, N. Kourkoumelis, S. Karkabounas, A. Evagelou and S.K. Hadjikakou*, Medicinal Chemistry Research , 2012, DOI 10.1007/s00044-012-0219-3.

 

[86] Synthesis, structural characterization and in vitro cytotoxic activity of the bis-(2,6-di-tert-butylphenol)tin(IV) dichloride and its complexes with heterocyclic thioamides.

D.B. Shpakovsky, C.N. Banti, G. Beaulieu-Houle, N. Kourkoumelis, S.K. Hadjikakou, M. Manoli, M.J. Manos, A.J. Tasiopoulos, E.R. Milaeva, K. Charalabopoulos, T. Bakas, I.S. Butler and N Hadjiliadi, Dalton Transaction, 2012, 10.1039/c2dt31527k.

 

[87] Synthesis and structural characterization of new Cu(I) complexes with the antithyroid drug 6-n-propyl-thiouracil. Study of the Cu(I)-catalyzed intermolecular cycloaddition of iodonium ylides towards benzo[b]furans with pharmaceutical implementations.

K. Paizanos, D. Charalampou, N. Kourkoumelis, D. Kalpogiannaki, L. Hadjiarapoglou, A. Spanopoulou, K. Lazarou, M.J. Manos, A.J. Tasiopoulos, M. Kubicki, S.K. Hadjikakou, Inorg Chem., 2012 dx.doi.org/10.1021/ic3014255

 

[88] Structural and in vitro biological studies of organotin(IV) precursors; Selective inhibitory activity against human breast cancer cells, positive to estrogen receptors.

V.. Balas, C.N. Banti, N. Kourkoumelis, S.K. Hadjikakou, G.D Geromichalos, D. Sahpazidou, L. Male, M.B. Hursthouse, B. Bednarz, M. Kubicki, K. Charalabopoulos and N. Hadjiliadis, 2012, Austr. J. Chem., DOI: http://dx.doi.org/10.1071/CH12448. RESEARCH FRONT PAPER

 

[89] Comparative binding effects of aspirin at LOX with Cu-complex

E. Vrontaki, M. Simcic, S. Golic Grdadolnik, A. Afantitis, G. Melagraki, S.K. Hadjikakou, T. Mavromoustakos, Journal of Chemical Information and Modeling, 2012 DOI: dx.doi.org/10.1021/ci3002759

 

[90] The healing effect of four synthesized silver complexes on full thickness skin burns in a rat model

E. Gouma, E. Lykoudis, A. Batistatou, I.I. Verginadis, Y. Simos, L. Kyros4, S.. Hadjikakou, S. Karkabounas, A. Evangelou, 2012 submitted for publication

 

[91] Anti-proliferative and anti-tumor activity of silver(I) compounds

Christina N. Banti and Sotiris K. Hadjikakou, Metallomics, 2013, Metallomics, 2013, 5, 569 (CRITICAL REVIEW)

 

[92] Synthesis, characterization and biological activity of antimony(III) or bismuth(III) chloride complexes with dithiocarbamate ligands derived from thiuram degradation

I.I. Ozturk, C.N. Banti, N. Kourkoumelis, M.J. Manos, A.J. Tasiopoulos, A.M. Owczarzak, M. Kubicki, S.K. Hadjikakou, Polyhedron, 67 (2014) 89103

 

[93] Synthesis, Structural Characterization and Cytostatic Properties of N,N-Dicyclohexyldithiooxamide Complexes of Antimony(III) Halides (SbX3, X: Br or I)

I.I. Ozturk, O.S.Urgut, C.N. Banti,, N. Kourkoumelis, A.M. Owczarzak, M. Kubicki, S.K. Hadjikakou, polyhedron 70 (2014) 172179

 

[94] Synthesis, characterization and binding properties towards CT-DNA and Lipoxigenase, of mixed ligand silver(I) complexes with 2-mercapto-thiazole and its derivatives and triphenyphosphine.

L. Kyros, C.N. Banti, N. Kourkoumelis, M. Kubicki, I. Sainis and S.K. Hadjikakou, J Biol Inorg Chem (2014) 19:449464.

 

[95] Fundamental chemistry of iodine. The reaction of di-iodine towards thiourea and its methyl- derivative; formation of aminothiazoles and aminothiadiazoles through dicationic disulfides.

M. Biesiada, N. Kourkoumelis, A. Owczarzak, M. Kubicki, S.K. Hadjikakou, Dalton Trans., 2014, 43, 4790

 

[96] Novel metallo-therapeutics of the NSAID naproxen. Interaction with intracellular components that leads the cells to apoptosis

C.N. Banti, A.D. Giannoulis, N. Kourkoumelis, A.M. Owczarzak, M. Kubicki and S.K. Hadjikakou, Dalton Transactions, 2014, 43 (18), 6848 - 6863.

 

[97] Synthesis, redox properties and in vitro cytotoxicity of novel organotin complexes with 3,5-di-tert-butyl-4-hydroxyphenylthiolate ligand

D.B. Shpakovsky, C.N. Banti, E.M. Mukhatova, Yu.A. Gracheva, V.P. Osipova, N.T. Berberova, D.V. Albov, T.A. Antonenko, L.А Aslanov., E.R. Milaeva, S.K. Hadjikakou. Dalton Transactions, 2014 43, 6880-6890.

 

[98] Assessment of organotins against the linoleic acid of cell membrane, the intracellular glutathione and the nuclear CT-DNA.

C.N. Banti, E. Gkaniatsou, N. Kourkoumelis, M.J. Manos, A.J. Tasiopoulos, T. Bakas and S.K. Hadjikakou, 2014 Inorg Chim Acta, 423 (2014) 98106

 

[99] Synthesis, characterization and binding properties against the CT-DNA and Lipoxygenase of a novel silver iodide complex with 2-mercapto-benzothiazole. Possible implementation against the cells resistance through glutathione pathway

C.N. Banti, L. Kyros, G.D Geromichalos, N. Kourkoumelis, M. Kubicki and S.K. Hadjikakou*, European Journal of Medicinal Chemistry 77 (2014) 388-399.

 

[100] Antimony(III) halide complexes of thioureas; structures and biological activity.

A. Han, I.I. Ozturk, C. N. Banti, N. Kourkoumelis, M. Manoli, A. J. Tasiopoulos, A. M. Owczarzak, M. Kubicki, S. K. Hadjikakou, Polyhedron 79 (2014) 151160.

 

[101] Mono- and bi-nuclear copper(I) complexes of thio-nucleotide analogues and their catalytic activity on the synthesis of dihydrofurans with possible pharmaceutical implementations.

D.C. Charalampou, N. Kourkoumelis, L. Hadjiarapoglou, V. Dokorou, S. Skoulika, A. Owczarzak, M. Kubicki and S.K. Hadjikakou, Inorganic Chemistry 2014 53 (16), pp 83228333.

 

[102] Stability and binding effects of silver(I) complexes at lipoxygenase-1.

E. Vrontaki, G. Leonis, A. Avramopoulos, M.G. Papadopoulos, M. Simčič, S. Golič-Grdadolnik, A. Afantitis, G. Melagraki, S.K. Hadjikakou, T. Mavromoustakos, Journal of Enzyme Inhibition and Medicinal Chemistry, 2014 accepted for publication.

 

[103] Silver(I) metallo-drugs of anti-inflammatory agents which modulate cells function

C.N. Banti, A.D. Giannoulis, N. Kourkoumelis, A.M. Owczarzak, M. Kubicki and S.K. Hadjikakou. J. Inorg. Biochem., 2015, 142, 132144

 

[104] Mono-nuclear cis-Pd(II) chloride complex of the thio-nucleotide analogue 5-methyl-thiouracil and its biological activity.

C.N. Banti, D. Charalampou, N. Kourkoumelis, A. M. Owczarzak, M. Kubicki, S. K. Hadjikakou, N. Hadjilaidis. Polyhedron, 2015, 87, 251-258

 

[105] The Healing Effect of Four Different Silver Complexes on Full-thickness Skin Burns in a Rat Model

E. Gouma, A. Batistatou, I.I. Verginadis, Y.V. Simos, L. Kyros, S.K. Hadjikakou, S.Ch. Karkabounas, A.M. Evangelou, VN. Ragos, D. Peschos, in vivo, 2015, 29: 55-64

 

[106] Rational Drug Design Paradigms: The Odyssey for designing better Drugs

T. Kellici, D. Ntountaniotis, E. Vrontaki, G. Liapakis, P. Minakakis, G. Kokotos, S. Hadjikakou, A.G. Tzakos, A. Afantitis, G. Melagraki, V. Di Marzo, T. Mavromoustakos, Combinatorial Chemistry & High Throughput Screening, 2015, 18, 238-256.

 

[107] Novel mixed metal Ag(I)-Sb(III)-metallotherapeutics of the NSAIDs, aspirin and salicylic acid. Enhancement of their solubility and bioactivity by using the surfactant CTAB.

E.I. Gkaniatsou, C.N. Banti, N. Kourkoumelis, S. Skoulika M. Manoli, A.J. Tasiopoulos and S.K. Hadjikakou, J. Inrog Biochem 150, 2015, 108-11

[108] Recent advances on antimony(III/V) compounds with potential activity against tumor cells

S.K. Hadjikakou, I.I. Ozturk, C.N. Banti, N. Kourkoumlis and N. Hadjiliadis, J. Inrog Biochem 2015, 153, 293305.

 

2015-2020

 

[109] New Antimony(III) Halide Complexes with Dithiocarbamate Ligands Derived from Thiuram Degradation: The Effect of the molecule's close contacts on in vitro cytotoxic activity

O.S. Urgut, I.I. Ozturk, C.N. Banti, N. Kourkoumelis, M. Manoli, A.J. Tasiopoulos, S. K. Hadjikakou, Materials Science and Engineering C 58 (2016) 396408.

 

[110] New antibacterial, non-genotoxic materials, derived from the functionalization of the anti-thyroid drug methimazole with silver ions

I. Sainis, C.N. Banti, A.M. Owczarzak, L. Kyros, N. Kourkoumelis, M. Kubicki, S.K. Hadjikakou, Journal of Inorganic Biochemistry 160 (2016) 114124

 

[111] Addition of Tetraethylthiuram Disulfide to Antimony(III) Iodide; Synthesis, Characterization and Biological Activity

O.S. Urgut, I.I. Ozturk, C.N. Banti, N. Kourkoumelis, M. Manoli, A.J. Tasiopoulos, S.K. Hadjikakou, Inorganica Chimica Acta 443 (2016) 141150

 

[112] Novel bismuth compounds; Synthesis, characterization and biological activity against human adenocarcinoma cell lines

M. Arda, I.I. Ozturk, C.N. Banti, N. Kourkoumelis, M. Manoli, A.J. Tasiopoulos, S. K. Hadjikakou 2016 RSC Adv., 2016, 6, 2902629044

 

[113] Non Steroidal Anti-Inflammatory Drugs (NSAIDs) as ligands in metal complexes and their effect on the cellular level

Christina N. Banti and Sotiris K. Hadjikakou, European Journal of Inorganic Chemistry 2016 (19), pp. 3048-3071

 

[114] Nimesulide silver metallodrugs, containing the mitochondriotropic, triaryl derivatives of pnictogen; Anticancer activity against human breast cancer cells

Christina N. Banti, Constantina Papatriantafyllopoulou, Maria Manoli, Anastasios J. Tasiopoulos and Sotiris K. Hadjikakou, Inorg. Chem., 2016, 55 (17), pp 86818696.

 

[115] Structural, photolysis and biological studies of novel mixed metal Cu(I)-Sb(III) mixed ligand complexes.

V. Tsiatouras, C.N. Banti, A.M. Grześkiewicz, G. Rossos, N. Kourkoumelis, M. Kubicki and S.K. Hadjikakou, 2016 Journal of Photochemistry & Photobiology, B: Biology 163 (2016) 261-268

 

[116] Silver(I) complexes of methyl xanthate against human adenocarcinoma breast cancer cells.

Christina N. Banti, Nikolaos Kourkoumelis , Constantinos G. Tsiafoulis, Stavroula Skoulika, Sotiris K. Hadjikakou Polyhedron (2017), pp. 115-122 DOI information: 10.1016/j.poly.2016.09.056

 

[117] Platinum(II)-thiosemicarbazone metal-drugs may be overcome cell resistance through glutathione; Assessment of their activity against human adenocarcinoma cells.

M. Poyraz, S. Demirayak, C.N. Banti, M.J Manos, N Kourkoumelis and S.K. Hadjikakou, J Coord Chem., 2016 69, 35603579

 

[118] SAR studies on antimony(III) halide complexes with N-substituted thioureas derivatives

I.I. Ozturk, S. Yarar, C.N. Banti, N. Kourkoumelis, M.P. Chrysouli, M. Manol, A. J. Tasiopoulos, S.K. Hadjikakou, Polyhedron 123 (2017) 152161

 

[119] QSAR studies on antimony(III) halide complexes with N-substituted thioureas derivatives

I.I. Ozturk, S. Yarar, C.N. Banti, N. Kourkoumelis, M.P. Chrysouli, M. Manol, A. J. Tasiopoulos, S.K. Hadjikakou, Polyhedron 123 (2017) 152161

 

[120] Synthesis characterization and biological activity of mixed ligand silver(I) complex of 2-Benzimidazolyl-urea and triphenylphosphine

Mehmet Poyraz, Halil Berber, Christina N. Banti, Nikolaos Kourkoumelis, Manolis J. Manos and Sotiris K. Hadjikakou, Polyhedron 128 (2017) 95103

 

[121] Docking and structure activity relationship studies of NSAIDs. What does molecular docking reveal about IC50?

Chrysoula Mikra, Georgios Rossos, Sotirios K. Hadjikakou, Nikolaos Kourkoumelis, Letters in Drug Design & Discovery, 2017, 14, 949-958; DOI: 10.2174/1570180814666161207143231 

 

[122] N-(4-hydroxyphenyl)acetamide against di-iodine towards polyiodide dianion

Christina N. Banti, Nick Kourkoumelis, Catherine P. Raptopoulou, Vassilis Psycharis, Sotiris K. Hadjikakou, New J. Chem., 2017, 41, 5555-5564.

 

[123] Synthesis, characterization and biological activities of copper(II) complex of 2-Benzimidazolyl-urea and the nitrate salt of 2-Benzimidazolyl-urea

Mehmet Poyraz, Musa Sari, Christina N. Banti and Sotiris K. Hadjikakou, Journal of Molecular Structure 1146 (2017) 809-813

 

[124] Innovative material containing the natural product curcumin, with enhanced antimicrobial properties for active packaging.

A. Papadimitriou, I. Ketikidis, M.K. Stathopoulou, C.N. Banti, C. Papachristodoulou, L. Zoumpoulakis, S. Agathopoulos, G.V. Vagenas, S.K. Hadjikakou, Materials Science & Engineering C 84 (2017) 118122

 

[125] Synthesis, Characterization and Cytostatic Properties of Bismuth(III) Chloride Complexes with Heterocyclic Thioamides; A survey for Structure Activity Relationship

S. Yarar, I.I. Ozturk, C.N. Banti, N. Panagiotou, C. Papatriantafyllopoulou, M. Manoli, M.J. Manos, A.J. Tasiopoulos, S.K. Hadjikakou, Inorganica Chemica Acta,471, 2018, 23-33

 

[126] Chloro(triphenylphosphine)gold(I) a forefront reagent in gold chemistry as apoptotic agent for cancer cells

M.P. Chrysoul, C.N. Banti, N. Kourkoumelis, N. Panayiotou, A.J. Tasiopoulos, S.K. Hadjikakou, Journal of Inorganic Biochemistry 179 (2018) 107120

 

[127] New metalo-therapeutics of NSAIDs against human breast cancer cells.

Christina N. Banti, Constantina Papatriantafyllopoulou, Anastasios J. Tasiopoulos and Sotiris K. Hadjikakou, European Journal of Medicinal Chemistry 143 (2018) 1687-1701

 

[128] Silver complex of salicylic acid and its hydrogel-cream in wound healing chemotherapy.

Maria-Eleni K. Stathopoulou, Christina N. Banti, Nikolaos Kourkoumelis, Antonis Hatzidimitriou, Sotiris K. Hadjikakou, Journal of Inorganic Biochemistry 181 (2018) 4155

 

[129] Cytotoxic effect, antitumour activity and toxicity of organotin derivatives with ortho- or para- hydroxy-benzoic acids

Maria S Agiorgiti; Angelos Evangelou; Patra Vezyraki; Sotiris Hadjikakou; Vasiliki Kalfakakou; Ioannis Tsanaktsidis; Anna Batistatou; John Zelovitis; Yannis V Simos; Vasilios Ragos; Spyridon Karkabounas; Dimitrios Peschos, Medicinal Chemistry Research (2018) 27:11221130

 

[130] Silver ciprofloxacin (CIPAG): a successful combination of antibiotics in inorganic-organic hybrid for the development of novel formulations based on chemically modified commercially available antibiotics

I. Milionis, C.N. Banti, I. Sainis, C.P. Raptopoulou, V. Psycharis, N. Kourkoumeli and S.K. Hadjikakou, Journal of Biological Inorganic Chemistry, 2018, (2018) 23:705723 https://doi.org/10.1007/s00775-018-1561-9

 

[131] Polymeric assemblies from organotins acetate against DNA with possible implementation towards human breast cancer.

G.K. Latsis, C.N. Banti, C. Papatriantafyllopoulou, N. Panayiotou, . Tasiopoulos, . Douvalis, T. Baka3, S.K. HadjikakouInt. J. Mol. Sci. 2018, 19, 2055; doi:10.3390/ijms19072055

 

[132] A water - soluble silver(I) formulation as an effective disinfectant of contact lenses cases

M.P. Chrysouli, C.N. Banti, I. Milionis, D. Koumasi, I. Sainis, C.P. Raptopoulou, V. Psycharis, S.K. Hadjikakou, Materials Science & Engineering C 93 (2018) 902910

[133] Bismuth(III) Bromide Complexes of Thioamides: Synthesis, Characterization and Cytotoxic Properties

M. Cakmak, I.I. Ozturk, C.N. Banti, M. Manoli, E. Moushi, A.J. Tasiopoulos, A.M. Grześkiewicz, M. Kubicki, S.K. Hadjikakou, Main Group Met. Chem. 41, 2018, 143-154, 2018; aop, https://doi.org/10.1515/mgmc-2018-0035

 

[134] Prokaryotic diversity and abundance in the sediments of an eutrophic ancient european lake (lake pamvotis - Greece).

Anastasia Touka; Katerina Vareli; Maria Igglezou; Nikolaos Monokrousos; Dimitrios Alivertis; John M Halley; Sotiris Hadjikakou; Stathis Frillingos; Ioannis Sainis Open Journal of Ecology, 2018, 8, 537-578

 

[135] Preface to A Commemorative Issue in Honour of Professor Nick Hadjiliadis: Metal Complex Interactions with Nucleic Acids and/or DNA

Christina N. Banti and Sotiris K. Hadjikakou, Int. J. Mol. Sci. 2018, 19, 3815; doi:10.3390/ijms19123815

 

[136] The periodic table of urea derivative; Small molecules of zinc(II) and nickel(II) of diverse antimicrobial and antiproliferative applications.

Christina N. Banti, Mehmet Poyraz, I. Sainis, Musa Sari, G. Rossos, N. Kourkoumelis, and Sotiris K. Hadjikakou, Molecular Diversity, 2019, Accepted for publication

 

[137] NSAIDs in breast cancer chemotherapy; Antimony(V) salicylate a strong covalent DNA binder.

N.M. Polychronis, C.N. Banti, C.P. Raptopoulou, V. Psycharis, N. Kourkoumelis, S.K. Hadjikakou, Inorganica Chimica Acta 489 (2019) 3947.

 

[138] Diclofenac conjugates with biocides through silver(I) ions (CoMeDs); Development of an optimized reliable regression model for the evaluation of antiproliferative metallodrugs.

Christina N. Banti, Antonios G. Hatzidimitriou, Nikolaos Kourkoumelis, Sotiris K. Hadjikakou, J Inorg. Biochem. 194 (2019) 718.

 

[139] Anti-proliferative and antitumor activity of organotin compounds; The progress of last decade.

Christina N. Banti, Sotiris K. Hadjikakou, Tuba Sismanoglu and Nick Hadjiliadis, 2019, Journal of Inorganic Biochemistry 194 (2019) 114152.

 

[140] Synthesis, Characterization, Biological Evaluation and Docking Study of Novel Antimony(III) Iodide Complexes with Tetramethylthiourea and N-ethylthiourea

I.I. Ozturk, S. Yarar, M.G. Eser, D. Ceyhan, C.N. Banti, S.K. Hadjikakou, M. Manoli, E. Moushi, A.J. Tasiopoulos, Inorganica Chimica Acta 491 (2019) 1424.

 

[141] Evaluation of Genotoxicity by Micronucleus Assay in vitro and by Allium cepa Test in vivo

Christina N. Banti and Sotiris K. Hadjikakou, Bio-protocol, 2019, 9(14): e3311. DOI: 10.21769/BioProtoc.3311

 

[142] Structural Architectures and Biological Properties of Main Group Bismuth(III) Iodide Complexes with Heterocyclic Thioamides

Ibrahim I. Ozturk, Christina N. Banti, Sotiris K. Hadjikakou, Nick Panayiotou, Anastasios J. Tasiopoulos, Inorganica Chimica Acta 497 (2019) 119094

 

[143] An efficient disinfectant, composite material {SLS@[Zn3(CitH)2]} as ingredient for development of sterilized and non infectious contact lens

V.A. Karetsi, C.N. Banti, N. Kourkoumelis, C. Papachristodoulou, C.D. Stalikas, C.P. Raptopoulou, V. Psycharis, P. Zoumpoulakis, T. Mavromoustakos, I. Sainis, Sotiris K. Hadjikakou, Antibiotics 2019, 8, 213; doi:10.3390/antibiotics 8040213.

 

[144] Antiproliferative activity of organo-antimony(III)-copper(I) mixed conjugates, against human breast cancer cells.

C.N. Banti, V. Tsiatouras, K. Karanicolas, N. Panagiotou, A.J. Tasiopoulos, N. Kourkoumelis, S.K. Hadjikakou, Molecular Diversity, 2019, https://doi.org/10.1007/s11030-019-10014-z.

 

[145] Fluorescence of copper(I) and mixed valence copper(I/II) complexes with dipicolinic acid and their catalytic activity on catechol oxidation.

K. Moschovitis, C.N. Banti, N. Kourkoumelis, E. Moushi, T. Lazaridis and S.K. Hadjikakou, , Inorganica Chimica Acta 2020, Article 119209

 

[146] Conjugation of penicillin-G with silver(I) ions expands its antimicrobial activity, against Gram negative bacteria.

I. Ketikidis, C.N. Banti, N. Kourkoumelis, C.G. Tsiafoulis, C. Papachristodoulou, A.G. Kalampounias, S.K. Hadjikakou, Antibiotics, 2020, 9, 25; doi:10.3390/antibiotics9010025

 

[147] pHEMA@AGMNA-1: a novel material for the development of non infectious contact lens

A.K. Rossos, C.N. Banti, A. Kalampounias, C. Papachristodoulou, K. Kordatos, P. Zoumpoulakis, T. Mavromoustakos, N. Kourkoumelis and S.K. Hadjikakou, Materials Science & Engineering C 111 (2020) 110770

 

[148] Study of penicillin degradation mechanism upon interaction with silver(I) ions

C.N. Banti, I. Ketikidis, S.K. Hadjikakou, A.G. Hatzidimitriou, A.M. Grześkiewicz, M Kubicki, N. Hadjiliadis. Inorganica Chimica Acta 509 (2020) 119683

 

[149] Amantadine copper(II) chloride conjugate with possible implementation in influenza virus inhibition

C.N. Banti, N. Kourkoumelis, A.G. Hatzidimitriou, I. Antoniadou, A. Dimou, M. Rallis, A. Hofmann, M. Schmidtke, K. McGuire, D. Busath, A. Kolocouris and S.K. Hadjikakou, Polyhedron 185 (2020) 114590

 

[150] Ciprofloxacin conjugated to diphenyltin(IV); A novel formulation with enhanced antimicrobial activity.

M.P. Chrysouli, C.N. Banti, N. Kourkoumelis, E.E.Moushi, A.J. Tasiopoulos, A. Douvalis, C. Papachristodoulou, A.G. Hatzidimitriou, T. Bakas, S.K. Hadjikakou, Dalton Transactions, 2020, 49, 11522 - 11535, DOI: 10.1039/d0dt01665a

 

[151] Tetracycline water soluble formulations with enhanced antimicrobial activity

A.Meretoudi, C.N. Banti, P. Siafarika, A.G. Kalampounias, S.K. Hadjikakou, Antibiotics 2020, 9, 845; doi:10.3390/antibiotics9120845

 

[152] Utilization of metal complexes formed by copper(II) acetate or nitrate, for the urea assay.

Koralia M. Sarakinou, Christina N. Banti, Antonis G. Hatzidimitriou, Sotiris K. Hadjikakou, 2020, Inorganica Chimica Acta 517 (2020) 120203