LABORATORY OF BIOLOGICAL INORGANIC CHEMISTRY (BIC)
APPLIED BIOINORGANIC CHEMISTRY GROUP (ABC GROUP)
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Dr. Sotiris K. Hadjikakou, Professor Laboratory of Biological Inorganic Chemistry Department of Chemistry University of Ioannina, Greece tel. xx-30-26510-08374, xx-30-26510-08362. Fax xx-30-26510-08786 e-mail: shadjika@uoi.gr http://users.uoi.gr/shadjika/Hadjikakou_1/Hadjikakou_01.htm https://myweb.uoi.gr/shadjika/
Coordinator of the Graduate Program in Biological Inorganic Chemistry
Institute of Materials Science and Computing (I.M.S.C.) https://urci.unit.uoi.gr/imsc/en/members/members.html
Research Ranking (December 6th, 2021) Among Top Chemistry Scientists in Greece
Editor Elsevier: Inorganic Chemistry Communications (Inorg Chem Comm)
Member of the editorial boards: Elsevier: Journal of Inorganic Biochemistry (JIB) MDPI: International Journal of Molecular Sciences-Biochemistry (IJMS) MDPI: Antibiotics (Antibiotics)
Guest Editor in the Special Issues: IJMS (MDPI): Recent Advances in Metal Based Drugs IJMS (MDPI):Metal Complex Interactions with Nucleic Acids and/or DNA Molecules (MDPI): Antimicrobial Materials with Medical Applications IJMS (MDPI): Antimicrobial Materials with Medical Applications Antibiotics (MDPI): Silver and Gold Compounds as Antibiotics "
Member of Scientific Societies [1] Member of the Greek Chemists Association (AGC) (Greek branch of the European Chemical Society (EuChemS)) [2] Member of the Hellenic Society of Medicinal Chemistry (HSMC) (Greek branch of the European Federation of Medicinal Chemistry and Chemical Biology (EFMC)) [3] Member of the Society of Biological Inorganic Chemistry (SBIC)
Member of the International Advisory Boards of the Scientific conference [1] International Meeting on Halogen Chemistry HALCHEM, 2006- [2] Eurasia Conference on Chemical Sciences EuAsC2S, 2012- [3] International Symposium on Applied Bioinorganic Chemistry ISABC, 2017-
Member of Scientific Networks [1] COST Action CM1105 "Functional metal complexes that bind to biomolecule", Member of the Working Group "WG 4: Interactions of metallo-drugs on the cellular level" at [2] COST Action CA15114 (National Representative) «Anti-Microbial Coating Innovations to Prevent Infectious Diseases (AMICI) Member of the Working Group "WG 1: Antimicrobial Materials Safe-by-Design" [3] COST Action CIG15114 “e-PlatformePlatform for a “test bed” tool across EU for antimicrobial coating solutions in health care entering to the market” [4] COST Action CA17104 (STRATAGEM): “New diagnostic and therapeutic tools against multidrug resistant tumours” [5]COST Action CA21145 - European Network for diagnosis and treatment of antibiotic-resistant bacterial infections (EURESTOP) [6] COST Action CA21115 (National Representative)- Iron-sulphur (FeS) clusters: from chemistry to immunology (FeSImm ChemNet)" |
Highlights:
New Apoptosis Inducers Containing Anti-inflammatory Drugs and Pnictogen Derivatives: A New Strategy in the Development of Mitochondrial Targeting Chemotherapeutics Christina N. Banti, Constantina Papatriantafyllopoulou, Christina Papachristodoulou, Antonios G. Hatzidimitriou, and Sotiris K. Hadjikakou, J. Med. Chem. 2023, 66, 4131−4149
Our protocol is reprinted in Microbiology Bio-protocol Selections 2022, a curated series of the 26 methods most used by Bio-protocol’s community over the past year 2021.
The research Project of our group: Design and development of new formulations based on natural products as additives in contact lenses, for the treatment of microbial keratitis is Co‐financed by the European Regional Development Fund of the European Union and Greek national funds through the Operational Program Competitiveness, Entrepreneurship and Innovation, under the call RESEARCH– CREATE - INNOVATE (project code:Τ1EDK-02990)»
Hydrogels containing water soluble conjugates of silver(I) ions with amino acids, metabolites or natural products for non infectious contact lenses C. N. Banti, M. Kapetana, C. Papachristodoulou, C. P. Raptopoulou, V. Psycharis, P. Zoumpoulakis, T. Mavromoustakos and S. K. Hadjikakou Dalton Trans., 2021, 50, 13712–13727
Ciprofloxacin conjugated to diphenyltin(IV): a novel formulation with enhanced antimicrobial activity M.P. Chrysouli, C.N. Banti, N. Kourkoumelis, E.E. Moushi, A.J. Tasiopoulos, A. Douvalis, C. Papachristodoulou, A.G. Hatzidimitriou, T. Bakas and S.K. Hadjikakou Dalton Trans., 2020, 49, 11522–11535
Synthesis, Structural Characterization and Cytostatic Properties of N,N-Dicyclohexyldithiooxamide Complexes of Antimony(III) Halides (SbX3, X: Br or I) I.I. Ozturk, O.S. Urgut, C.N. Banti, N. Kourkoumelic, A.M. Owczarzak, M. Kubicki, and S.K. Hadjikakou Polyhedron Volume 70, 9 March 2014, Pages 172–179
Mixed ligands silver(I) complexes with anti-inflammatory agents which can bind to lipoxygenase and calf thymus-DNA, modulating their function, inducing apoptosis. C.N. Banti, A. D. Giannoulis, N. Kourkoumelis, A. M. Owczarzak, M. Poyraz, M. Kubicki, K. Charalabopoulos and S. K. Hadjikakou |
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Our recent papers: pHEMA@AGMNA-1: A novel material for the development of antibacterial contact lens A.K. Rossos, C.N. Banti, A. Kalampounias, C. Papachristodoulou, K. Kordatos, P. Zoumpoulakis, T. Mavromoustakos, N. Kourkoumelis, S.K. Hadjikakou Materials Science & Engineering C 111 (2020) 110770 |
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Conjugation of Penicillin-G with Silver(I) Ions Expands Its Antimicrobial Activity against Gram Negative Bacteria Ioannis Ketikidis, Christina N. Banti, Nikolaos Kourkoumelis, Constantinos G. Tsiafoulis, Christina Papachristodoulou, Angelos G. Kalampounias and Sotiris K. Hadjikakou Antibiotics 2020, 9, 25; doi:10.3390
Diclofenac conjugates with biocides through silver(I) ions (CoMeD's); Development of a reliable model for the prediction of anti-proliferation of NSAID's-silver formulations. Christina N. Banti, Antonios G. Hatzidimitriou, Nikolaos Kourkoumelis, Sotiris K. Hadjikakou Journal of Inorganic Biochemistry 194 (2019) 7–18
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